ACAP3
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Official Full Name
ArfGAP with coiled-coil, ankyrin repeat and PH domains 3
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Synonyms
ACAP3; ArfGAP with coiled-coil, ankyrin repeat and PH domains 3; centaurin, beta 5 , CENTB5; arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 3; KIAA1716; Centaurin, beta 5; Centaurin-beta-5; CENTB5; Cnt-b5; OTTHUMP00000002288;
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | ACAP3-9275H | Recombinant Human ACAP3, His-tagged | E.coli | His | C-term-348a.a. |
- Involved Pathway
- Protein Function
- Interacting Protein
ACAP3 involved in several pathways and played different roles in them. We selected most pathways ACAP3 participated on our site, such as Endocytosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with ACAP3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Endocytosis | CHMP3;RAB11FIP4;VPS37C;CHMP5B;CXCR2;SMURF1;CAPZA1;PIP5K1AA;CYTH1B |
ACAP3 has several biochemical functions, for example, GTPase activator activity, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ACAP3 itself. We selected most functions ACAP3 had, and list some proteins which have the same functions with ACAP3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| GTPase activator activity | SMAP2;THY1;SIPA1L1;ARHGAP44;RGS9;TBC1D16;SOS1;TBC1D3;TIAM2 |
| metal ion binding | BGLAP2;PDSS1;NCALDB;ZFP451;LIMK1A;ZNF468;HAND2;CYCS;PVALB4 |
ACAP3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ACAP3 here. Most of them are supplied by our site. Hope this information will be useful for your research of ACAP3.
ITGB3BP; TAB1; SLC35G2
- Q&As
- Reviews
Q&As (10)
Ask a questionThe recommended protein concentration for using the recombinant ACAP3 protein in experiments may vary depending on the specific experimental conditions, but a typical working concentration range is 0.1-10 μg/mL.
The expression of ACAP3 has been shown to be regulated by a variety of factors, including growth factors, cytokines, and cellular stress. For example, ACAP3 expression has been found to be upregulated in response to stimulation with epidermal growth factor (EGF) and platelet-derived growth factor (PDGF).
ACAP3 has been implicated in the regulation of exocytosis by interacting with proteins involved in vesicle fusion and secretion, such as the exocyst complex and the SNARE proteins. ACAP3's interaction with these proteins may help to coordinate the delivery of cargo to the plasma membrane and promote efficient secretion.
Yes, the recombinant ACAP3 protein can be used for functional studies, as it is a biologically active protein that is capable of binding to other proteins and performing its cellular functions.
The His tag promotes protein solubility and is used for affinity purification, it may or may not affect protein activity. If you are concerned that the tag may interfere with protein activity, Creative BioMart can also provide custom tag-free ACAP3 protein service.
Recombinant ACAP3 protein is primarily used as a research tool and is not approved for diagnostic or therapeutic purposes.
Creative BioMart offers a bulk quote for each product available on our website. For specific prices, please contact our sales representatives.
The recombinant ACAP3 protein is ready-to-use and does not require any additional processing or purification before use.
Yes, we offer MSDS files and data sheets with detailed product information.
ACAP3 has been shown to regulate clathrin-mediated endocytosis by binding to clathrin and dynamin, two key proteins involved in this process. ACAP3's interaction with dynamin is thought to be important for the formation of endocytic vesicles, while its interaction with clathrin may modulate the timing and efficiency of vesicle formation.
Customer Reviews (3)
Write a reviewThe recombinant human ACAP3 protein I purchased from Creative BioMart was easy to work with and highly effective. I highly recommend this product to others.
I appreciate Creative BioMart's commitment to providing high-quality products at an affordable price. Their recombinant human ACAP3 protein is a great value for the money.
The technical support team was extremely helpful in customizing the recombinant ACAP3 protein to my specific needs. The final product worked perfectly for my project.
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