Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

Acot2

  • Official Full Name

    acyl-CoA thioesterase 2

  • Synonyms

    ACOT2; MTE1; PTE2; CTE1A; PTE2A; CTE-IA; ZAP128; acyl-coenzyme A thioesterase 2, mitochondrial; long-chain acyl-CoA thioesterase 2; mitochondrial acyl-CoA thioesterase 1; acyl-coenzyme A thioester hydrolase 2a; peroxisomal long-chain acyl-coA thioesterase 2;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Cynomolgus Monkey
  • Human
  • Rat
  • E.coli
  • E.Coli or Yeast
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human ACOT2-3139H Recombinant Human ACOT2, His-tagged E.Coli or Yeast His 483
Human ACOT2-12H Recombinant Human ACOT2 protein, GST-tagged Wheat Germ GST
Human ACOT2-3247H Recombinant Human ACOT2 protein, His-tagged E.coli His 222-483 aa
Human ACOT2-583HF Recombinant Full Length Human ACOT2 Protein, GST-tagged In Vitro Cell Free System GST 483 amino acids
Rat Acot2-3138R Recombinant Rat Acot2, His-tagged E.Coli or Yeast His 453
Cynomolgus Monkey ACOT2-267C Recombinant Cynomolgus ACOT2 Protein, His-tagged Mammalian Cell His
Cynomolgus Monkey ACOT2-266C Recombinant Cynomolgus ACOT2 Protein, His-tagged Mammalian Cell His
Cynomolgus Monkey ACOT2-16C Recombinant Cynomolgus Monkey ACOT2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Cynomolgus Monkey ACOT2-16C-B Recombinant Cynomolgus Monkey ACOT2 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Acot2 Related Articles

Acot2 involved in several pathways and played different roles in them. We selected most pathways Acot2 participated on our site, such as Biosynthesis of unsaturated fatty acids, Fatty Acyl-CoA Biosynthesis, Fatty acid elongation, which may be useful for your reference. Also, other proteins which involved in the same pathway with Acot2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Biosynthesis of unsaturated fatty acidsSCD;PTPLAD1;ELOVL2;FADS2;ACOX3;Scd2;ACOT1;PTPLA;ACOT5
Fatty Acyl-CoA BiosynthesisACOT11A;ACOT7;ACSF3;ACOT2;SLC25A1;ACSF2;THEM5;ACOT10;ELOVL1A
Fatty acid elongationELOVL4A;ACOT5;ELOVL3;HADHAB;ACOT2;TECRB;ELOVL7;ACAA2;MECR
Fatty acid, triacylglycerol, and ketone body metabolismACOT10;ACOT2;CDK19;MMAA;MED29;MED21;ACOT9.2;ACOT12;ANKRD1
Metabolic pathwaysATP6V0E2;PTS;CYP2C45;DNMT4;AMY1A;PHYKPL;CYP3A7-CYP3AP1;ACER1;NDUFV3
MetabolismACOT9.2;NFYBB;DSEL;ITPKB;GLB1L;UCP3;PLD6;DUT;ACOT2
Metabolism of lipids and lipoproteinsMED22;FABP11B;APOEB;CYP2U1;LMF1;DHCR24;ARV1;CHKB;ACOT8
Ovarian steroidogenesisFSHR;STAR;LHB;FSHB;BMP6;GDF9;Adcy4;INS1;AKR1C3

Acot2 has several biochemical functions, for example, acyl-CoA hydrolase activity, carboxylic ester hydrolase activity, palmitoyl-CoA hydrolase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Acot2 itself. We selected most functions Acot2 had, and list some proteins which have the same functions with Acot2. You can find most of the proteins on our site.

Function Related Protein
acyl-CoA hydrolase activityACOT2;ACOT8;ACOT11;ACOT10;ACOT5;ACOT1;ACSBG2
carboxylic ester hydrolase activityCES2;AADACL2;ACOT6;ACOT1;NCEH1A;CES1D;LIPH;ESD;AADACL4
palmitoyl-CoA hydrolase activityGNPAT;ACOT5;THEM5;ACOT1;ACOT8;ACOT2;PPT1;ACOT7;BAAT
receptor bindingFGF24;TDGF1;TIGIT;UFD1L;LPL;ACOX1;LBP;PPY;MBL2

Acot2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Acot2 here. Most of them are supplied by our site. Hope this information will be useful for your research of Acot2.

ZNF277

Maloberti, P; Lozano, RC; et al. Concerted regulation of free arachidonic acid and hormone-induced steroid synthesis by acyl-CoA thioesterases and acyl-CoA synthetases in adrenal cells. EUROPEAN JOURNAL OF BIOCHEMISTRY 269:5599-5607(2002).
Yamada, J; Kurata, A; et al. Purification, molecular cloning, and genomic organization of human brain long-chain acyl-CoA hydrolase. JOURNAL OF BIOCHEMISTRY 126:1013-1019(1999).
  • Q&As
  • Reviews

Q&As (13)

Ask a question
What are the potential medical applications of ACOT2 protein? 08/08/2022

ACOT2 protein may have therapeutic implications for the treatment of metabolic disorders such as obesity and diabetes, as well as certain types of cancer. It may also be a target for drug development to enhance fatty acid oxidation.

Can ACOT2 protein be used in diagnostic tests or assays? 09/04/2021

ACOT2 protein may be used as a diagnostic biomarker for metabolic disorders or cancer, but more research is needed to establish its clinical utility.

What are some challenges or limitations to using ACOT2 protein in medicine or biotechnology? 03/17/2021

One of the challenges is the lack of specificity of current inhibitors and modulators of ACOT2 activity. Additionally, more research is needed to fully understand the role of ACOT2 in various diseases and to validate its potential as a therapeutic target.

Can ACOT2 protein be used in diagnostic tests? 10/23/2020

ACOT2 protein is not commonly used in diagnostic tests, but changes in its expression or activity may serve as biomarkers for certain diseases or conditions.

What techniques are used to study ACOT2 protein and its function? 01/02/2020

Common techniques used to study ACOT2 protein and its function include molecular biology and biochemistry techniques such as gene expression analysis, enzyme assays, and protein purification. Imaging techniques such as fluorescent microscopy may also be used to visualize ACOT2 localization and function within cells.

How might ACOT2 protein be used in personalized medicine? 12/08/2019

ACOT2 protein expression levels may have the potential to identify individuals who would benefit from specific treatments for metabolic disorders or cancer, allowing for personalized treatment plans.

Are there any drugs or compounds that target or modulate ACOT2 protein activity? 08/14/2019

There are currently no FDA-approved drugs that target ACOT2 protein activity, but researchers are investigating potential inhibitors and modulators of ACOT2 as therapeutic agents for metabolic disorders and cancer.

What are some potential applications for ACOT2 protein in biotechnology or medicine? 07/20/2018

ACOT2 protein has potential applications in drug development for metabolic disorders and obesity. It also has applications in research as a biomarker for poor prognosis in cancer patients and as a therapeutic target for cancer treatment.

Are there any known mutations or variations in the ACOT2 gene that are linked to disease? 08/20/2017

There have been some studies that suggest variations in the ACOT2 gene may be associated with increased risk for obesity and metabolic disorders. However, more research is needed to establish these links definitively.

What research areas are exploring the potential of ACOT2 protein? 03/09/2016

Research areas exploring the potential of ACOT2 protein include metabolic disorders such as diabetes and obesity, as well as cancer research and drug development.

What are some potential future directions for research on ACOT2 protein? 12/02/2015

There is ongoing research to further understand ACOT2's role in lipid metabolism and its potential therapeutic targets in diseases such as obesity and cancer. Additionally, there is interest in developing more specific and effective inhibitors or modulators of ACOT2 activity for potential therapeutic use.

What challenges exist in targeting ACOT2 protein for drug development? 04/24/2015

One challenge is understanding the complex role of ACOT2 in lipid metabolism and its potential off-target effects on other metabolic pathways. Developing selective ACOT2 inhibitors or modulators with good pharmacokinetic properties is also a challenge.

How is ACOT2 protein regulated in the body? 04/04/2015

ACOT2 protein expression and activity are regulated by a variety of factors, including hormones, nutrient availability, and cellular energy status. Other enzymes and proteins involved in lipid metabolism may also impact ACOT2 activity.

Customer Reviews (0)

Write a review

Ask a Question for All Acot2 Products

Required fields are marked with *

My Review for All Acot2 Products

Required fields are marked with *

logo

FOLLOW US

Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /

Stay Updated on the Latest Bioscience Trends