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ACSM4

  • Official Full Name

    acyl-CoA synthetase medium-chain family member 4

  • Synonyms

    ACSM4; acyl-CoA synthetase medium-chain family member 4; acyl-coenzyme A synthetase ACSM4, mitochondrial; similar to olfactory specific medium chain acyl CoA synthetase;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • E.Coli or Yeast
  • HEK293
  • HEK293T
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • Myc|DDK
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human ACSM4-3136H Recombinant Human ACSM4, His-tagged E.Coli or Yeast His 580
Human ACSM4-1024H Recombinant Human ACSM4 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Mouse ACSM4-1233M Recombinant Mouse ACSM4 Protein Mammalian Cell His
Mouse Acsm4-1511M Recombinant Mouse Acsm4 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse ACSM4-277M Recombinant Mouse ACSM4 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse ACSM4-277M-B Recombinant Mouse ACSM4 Protein Pre-coupled Magnetic Beads HEK293
Rat ACSM4-475R Recombinant Rat ACSM4 Protein Mammalian Cell His
Rat ACSM4-131R Recombinant Rat ACSM4 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat ACSM4-131R-B Recombinant Rat ACSM4 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein

ACSM4 involved in several pathways and played different roles in them. We selected most pathways ACSM4 participated on our site, such as Butanoate metabolism, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with ACSM4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Butanoate metabolismACSM4;OXCT1B;HADH;EHHADH;GAD1B;OXCT1A;HMGCS2;OXCT2B;ACSM2B
Metabolic pathwaysPCK2;ENPP7;COX5B;IMPAD1;CYP51A1;SMPD4;FUT9A;DPYS;PTGS2B

ACSM4 has several biochemical functions, for example, ATP binding, butyrate-CoA ligase activity, fatty-acyl-CoA synthase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ACSM4 itself. We selected most functions ACSM4 had, and list some proteins which have the same functions with ACSM4. You can find most of the proteins on our site.

Function Related Protein
ATP bindingNLK2;EPHB1;ATP6AP1;ROR2;FGFR3;TEP1;CHEK1;SPO11;SPATA5L1
butyrate-CoA ligase activityAcsm2a;ACSM2B;AACS;ACSM2;ACSM3;ACSM4;PPP1CA;ACSM1;ACSM5
fatty-acyl-CoA synthase activityACSM4;SLC27A3
metal ion bindingZNF781;ZBTB7A;NDUFV1;CAPN8;NME6;ZMYND19;CRYABA;GLRX5;ACY1

ACSM4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ACSM4 here. Most of them are supplied by our site. Hope this information will be useful for your research of ACSM4.

  • Q&As
  • Reviews

Q&As (10)

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How does ACSM4 interact with other lipid metabolism-related enzymes and transporters, such as fatty acid-binding protein (FABP) and ATP-binding cassette transporter A1 (ABCA1)? 10/22/2022

ACSM4 has been shown to interact with FABP and ABCA1, among other lipid metabolism-related proteins, and may play a role in regulating the transport and metabolism of fatty acids in cells.

How does ACSM4 differ from other members of the acyl-CoA synthetase family? 06/12/2022

ACSM4 has a unique substrate specificity compared to other members of the acyl-CoA synthetase family, preferring long-chain fatty acids with unsaturated bonds.

How does ACSM4 contribute to the regulation of lipid droplet formation and turnover in cells? 05/13/2022

ACSM4 has been shown to interact with other proteins involved in lipid droplet formation and turnover, such as perilipin and adipose triglyceride lipase (ATGL), and may play a role in promoting the breakdown and utilization of stored lipids.

How is ACSM4 expression regulated? 11/19/2021

The regulation of ACSM4 expression is not well understood, but it may be influenced by dietary factors and metabolic status.

What is the relationship between ACSM4 and autophagy? 11/15/2021

ACSM4 has been shown to regulate autophagy, a process by which cells break down and recycle damaged or unnecessary cellular components. Specifically, ACSM4 has been shown to promote the clearance of damaged mitochondria via autophagy in some cell types.

What is the tissue distribution of ACSM4 expression? 10/18/2021

ACSM4 is expressed in a variety of tissues, including the liver, kidney, heart, and skeletal muscle.

What is the relationship between ACSM4 and AMP-activated protein kinase (AMPK)? 10/17/2021

ACSM4 has been shown to be a downstream target of AMPK, a key regulator of cellular energy metabolism. AMPK activation can lead to increased ACSM4 expression and activity, which may help cells better respond to metabolic stress.

What is the role of ACSM4 in regulating lipid metabolism in skeletal muscle cells? 04/01/2021

ACSM4 is thought to play a role in promoting lipid uptake and oxidation in skeletal muscle cells, which can help improve insulin sensitivity and glucose metabolism.

How is ACSM4 involved in inflammation? 02/16/2020

ACSM4 has been implicated in the regulation of inflammation in various tissues. It may play a role in modulating the production of inflammatory cytokines and other mediators.

What is the relationship between ACSM4 expression and insulin resistance? 07/20/2018

Studies have suggested that ACSM4 expression may be upregulated in insulin-resistant states, such as obesity and type 2 diabetes. The exact mechanism by which ACSM4 contributes to insulin resistance is not well understood.

Customer Reviews (5)

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Reviews
09/01/2020

    Its exceptional characteristics and superior performance have greatly enhanced the accuracy and validity of our findings.

    07/29/2020

      Using this protein is like having a cup of coffee with your favorite lab mate. It's comforting, reliable, and gives you that extra boost in your research!

      05/09/2020

        Simplified workflows, increased experimental efficiency.

        08/01/2019

          Quality product, reasonable pricing, and exceptional service. A winning combination.

          10/25/2018

            This protein has proven to be an invaluable asset in our laboratory.

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