|Official Full Name||ARP2 actin-related protein 2 homolog (yeast)|
|Background||The specific function of this gene has not yet been determined; however, the protein it encodes is known to be a major constituent of the ARP2/3 complex. This complex is located at the cell surface and is essential to cell shape and motility through lamellipodial actin assembly and protrusion. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]|
|Synonyms||ACTR2; ARP2 actin-related protein 2 homolog (yeast); ARP2; actin-related protein 2; actin-like protein 2;|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
actr2 involved in several pathways and played different roles in them. We selected most pathways actr2 participated on our site, such as Axon guidance, B Cell Receptor Signaling Pathway, CDC42 signaling events, which may be useful for your reference. Also, other proteins which involved in the same pathway with actr2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Axon guidance||COL6A1; PLXNB2; SCN3A; ARPC5; NTN1A; CSF2; GSK3B; PAQR3B; CLASP1; EPHA2|
|B Cell Receptor Signaling Pathway||CD81; PLEKHA1; TTC6; ITK; PDK2B; PPP3CA; CARD11; CR2; PIK3CA; HRAS|
|CDC42 signaling events||PAK4; BAIAP2; ACTR3; ARPC1B; TNK2; IQGAP3; ARPC3; CFL1; CDC42BPA; ARPC4|
|Developmental Biology||DUSP4; MED7; EFNA4; SCN4A; SPRED1; CTNNA2; DPYSL4; ARPC4; CLASP1; PSPN|
|EPH-Ephrin signaling||EPHB4B; EFNA4; EFNB2A; KALRN; ARHGEF28; MYL12A; ARPC5; ACTR2; EFNA3B; EPHB4A|
|EPHB-mediated forward signaling||ACTR2B; ARHGEF28; ARPC1A; ACTR3; ARPC4; KALRN; EPHB3A; EFNB3; EPHB4A; ARPC2|
|ErbB1 downstream signaling||MAP3K2; EGR1; WASF2; EPS8; CHN2; NCKAP1; ABI1; ACTR3; ACTR2; ARF4|
|Fcgamma receptor (FCGR) dependent phagocytosis||WASF2; ACTR3; IgG3; PPAPDC1A; MYO1C; NCKAP1; WASF3; ABI1A; ARPC1A; ACTR2|
actr2 has several biochemical functions, for example, ATP binding, contributes_to actin filament binding, structural constituent of cytoskeleton. Some of the functions are cooperated with other proteins, some of the functions could acted by actr2 itself. We selected most functions actr2 had, and list some proteins which have the same functions with actr2. You can find most of the proteins on our site.
|ATP binding||STK4; NEK4; DALRD3; MYHZ1.2; LMTK2; ABCG2A; EPHA2; CSNK1A1L; CCT6B; IGHMBP2|
|contributes_to actin filament binding||ACTR2; ACTR3; ARPC4; ARPC5; MYH10; ARPC1B; MYH9; ARPC3; ARPC2|
|structural constituent of cytoskeleton||TUBGCP4; TUBA1L; TUBB4A; CYLC2; KRT20; COX4I2; TUBA8L3; TUBE1; TUBA8L4; TLN1|
actr2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with actr2 here. Most of them are supplied by our site. Hope this information will be useful for your research of actr2.
WASL; EIF1B; BCAR3; HLA-B; BAK1; ACTR3B; TNIK; TRAF6; ELF5; Flot1; PPP1R12A; ARPC1B; ARPC2; ARPC3; ARPC5; COBL; ATP6AP2; SVIL; ESR1; GSN