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Official Full Name aspartoacylase (aminocyclase) 3
Background Plays an important role in deacetylating mercapturic acids in kidney proximal tubules.
Synonyms ACY3; aspartoacylase (aminocyclase) 3; aspartoacylase-2; ACY 3; HCBP1; MGC9740; 0610006H10Rik; AA3; ACY-3; ACY3_HUMAN; Acylase III; Aminoacylase 3; Aminoacylase III; Aminoacylase-3; ASPA2; Aspartoacylase (aminoacylase) 3; Aspartoacylase 2; AW107362; EC 3.5.1.-; EC; Hepatitis C virus core binding protein 1; Hepatitis C virus core-binding protein 1; MGC108859; RGD1305394; OTTHUMP00000235614; OTTHUMP00000235615
    • Species :
    • Human
    • Mouse
    • Rat
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • Myc/DDK
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ACY3-164H Recombinant Human ACY3 protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human ACY3-263H Recombinant Human ACY3 Protein, GST-tagged Wheat Germ GST
    Human ACY3-26720TH Recombinant Human ACY3, His-tagged E.coli His
    Human ACY3-3577H Recombinant Human ACY3, His-tagged E.coli His
    Human ACY3-4301H Recombinant Human ACY3 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human ACY3-9043HCL Recombinant Human ACY3 293 Cell Lysate HEK293 N/A
    Human ACY3-9361H Recombinant Human ACY3, GST-tagged E.coli GST
    Mouse ACY3-1268M Recombinant Mouse ACY3 Protein Mammalian Cell His
    Mouse Acy3-1524M Recombinant Mouse Acy3 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Rat ACY3-498R Recombinant Rat ACY3 Protein Mammalian Cell His

    acy3 involved in several pathways and played different roles in them. We selected most pathways acy3 participated on our site, such as Aflatoxin activation and detoxification, Biological oxidations, Metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with acy3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Aflatoxin activation and detoxification CYP3A4; GGT6; DPEP2; ACY3.2; FAM84B; CYP2A13; GGTLC1; CYP3A5; DPEP1; PRKRA
    Biological oxidations CYP2AD2; AS3MT; CYP2F1; NAT2; GSTK1; ADH8A; CYP19A1; UGT1B1; CYP2J2; CYP11B1

    acy3 has several biochemical functions, for example, aminoacylase activity, hydrolase activity, acting on ester bonds, identical protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by acy3 itself. We selected most functions acy3 had, and list some proteins which have the same functions with acy3. You can find most of the proteins on our site.

    Function Related Protein
    aminoacylase activity DARS; ACY1; CAT; ASPA; ACY3
    hydrolase activity, acting on ester bonds ASPA; LIPN; APMAP; IAH1; CES1C; C11orf54; ESD; RAG1; PTER; PGAP3
    identical protein binding TYROBP; VWA2; ANXA4; SOD1; ALDH4A1; CALHM1; SQSTM1; MPST; HOMER1; PRPS2
    metal ion binding ZNF831; MAP2K2; FTR43; ZNF503; ZFAND5A; CYP4A12A; LMAN2; ZNF384L; ATP2A2B; SCRT2
    molecular_function CAR6; CTAG2; TMEM39B; DCUN1D4; TMEM14CB; AGPHD1; TMEM219; GM8720; FAM105A; FAM8A1
    protein binding ZNF317; SPRY4; UBE2O; WT1; NPY2R; U2AF2; ICA1; TSPAN2; ZFP64; CLN5

    acy3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with acy3 here. Most of them are supplied by our site. Hope this information will be useful for your research of acy3.


    Hiltunen, TP; Donner, KM; et al. Pharmacogenomics of Hypertension: A Genome-Wide, Placebo-Controlled Cross-Over Study, Using Four Classes of Antihypertensive Drugs. JOURNAL OF THE AMERICAN HEART ASSOCIATION 4:-(2015).
    Rise, ML; Nash, GW; et al. Variation in embryonic mortality and maternal transcript expression among Atlantic cod (Gadus morhua) broodstock: A functional genomics study. MARINE GENOMICS 18:3-20(2014).

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