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Official Full Name a disintegrin and metallopeptidase domain 21
Background May be involved in sperm maturation and/or fertilization. May also be involved in epithelia functions associated with establishing and maintaining gradients of ions or nutrients.
Synonyms ADAM21; a disintegrin and metallopeptidase domain 21; Adam31; disintegrin and metalloproteinase domain-containing protein 21; ADAM 21; ADAM 31; a disintegrin and metalloprotease domain 21; a disintegrin and metalloprotease domain (ADAM) 21; disintegrin and metalloproteinase domain-containing protein 31;
    • Species :
    • Human
    • Mouse
    • Rhesus Macaque
    • Source :
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ADAM21-23HCL Recombinant Human ADAM21 cell lysate N/A
    Human ADAM21-282H Recombinant Human ADAM21 Protein, GST-tagged Wheat Germ GST
    Mouse ADAM21-1285M Recombinant Mouse ADAM21 Protein Mammalian Cell His
    Rhesus Macaque ADAM21-233R Recombinant Rhesus monkey ADAM21 Protein, His-tagged Mammalian Cell His

    ADAM21 involved in several pathways and played different roles in them. We selected most pathways ADAM21 participated on our site, such as Fertilization, Interaction With The Zona Pellucida, Reproduction, which may be useful for your reference. Also, other proteins which involved in the same pathway with ADAM21 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Interaction With The Zona Pellucida ADAM21; ADAM30; OVGP1; ADAM20; ADAM2; ZP2; ZP3
    Reproduction Acr; CATSPER1; HVCN1; TMEM146; ADAM21; OVGP1; ZP2; IZUMO1; ADAM30; CATSPERG2

    ADAM21 has several biochemical functions, for example, metalloendopeptidase activity, metallopeptidase activity, zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ADAM21 itself. We selected most functions ADAM21 had, and list some proteins which have the same functions with ADAM21. You can find most of the proteins on our site.

    Function Related Protein
    metalloendopeptidase activity MEP1B; ADAMTS10; MEP1A; ADAMTS4; MMP8; BMP1B; ADAM10B; MIPEP; FAP; TLL2
    metallopeptidase activity ADAM10A; ADAM30; ADAM12; ADAMTS7; NPSN; PAPPAB; BMP1; CNDP2; PAPPAA; HE2
    zinc ion binding SIVA1; AGBL1; TRIM40; MMP7; RNF135; ZDHHC16B; DEF8; CAPNS2; L3MBTL4; PCGF2

    ADAM21 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ADAM21 here. Most of them are supplied by our site. Hope this information will be useful for your research of ADAM21.

    Yang, P; Baker, KA; et al. A disintegrin and metalloprotease 21 (ADAM21) is associated with neurogenesis and axonal growth in developing and adult rodent CNS. JOURNAL OF COMPARATIVE NEUROLOGY 490:163-179(2005).

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