ADAM21
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Official Full Name
a disintegrin and metallopeptidase domain 21
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Overview
May be involved in sperm maturation and/or fertilization. May also be involved in epithelia functions associated with establishing and maintaining gradients of ions or nutrients. -
Synonyms
ADAM21; a disintegrin and metallopeptidase domain 21; Adam31; disintegrin and metalloproteinase domain-containing protein 21; ADAM 21; ADAM 31; a disintegrin and metalloprotease domain 21; a disintegrin and metalloprotease domain (ADAM) 21; disintegrin and metalloproteinase domain-containing protein 31;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rhesus Macaque
- HEK293
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- N/A
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | ADAM21-282H | Recombinant Human ADAM21 Protein, GST-tagged | Wheat Germ | GST |
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| Human | ADAM21-23HCL | Recombinant Human ADAM21 cell lysate | N/A |
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| Human | ADAM21-873HF | Recombinant Full Length Human ADAM21 Protein, GST-tagged | In Vitro Cell Free System | GST | 772 amino acids |
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| Mouse | ADAM21-1285M | Recombinant Mouse ADAM21 Protein | Mammalian Cell | His |
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| Mouse | ADAM21-313M | Recombinant Mouse ADAM21 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Mouse | ADAM21-313M-B | Recombinant Mouse ADAM21 Protein Pre-coupled Magnetic Beads | HEK293 |
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| Rhesus Macaque | ADAM21-233R | Recombinant Rhesus monkey ADAM21 Protein, His-tagged | Mammalian Cell | His |
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| Rhesus Macaque | ADAM21-61R | Recombinant Rhesus Macaque ADAM21 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Rhesus Macaque | ADAM21-61R-B | Recombinant Rhesus Macaque ADAM21 Protein Pre-coupled Magnetic Beads | HEK293 |
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- Involved Pathway
- Protein Function
- Interacting Protein
- ADAM21 Related Articles
ADAM21 involved in several pathways and played different roles in them. We selected most pathways ADAM21 participated on our site, such as Fertilization, Interaction With The Zona Pellucida, Reproduction, which may be useful for your reference. Also, other proteins which involved in the same pathway with ADAM21 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Fertilization | OVGP1;ZP2;CATSPER2;IZUMO1;CATSPER3;IZUMO4;ADAM20;CATSPERG2;ADAM21 |
| Interaction With The Zona Pellucida | ADAM21;ADAM2;ZP2;ADAM30;OVGP1;ZP3;ADAM20 |
| Reproduction | IZUMO1;ADAM2;CATSPER3;CATSPERG1;ZP3;CATSPER2;CATSPERB;ADAM30;OVGP1 |
ADAM21 has several biochemical functions, for example, metalloendopeptidase activity, metallopeptidase activity, zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ADAM21 itself. We selected most functions ADAM21 had, and list some proteins which have the same functions with ADAM21. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| metalloendopeptidase activity | MIPEP;NPSN;MMP14;Adam6;ZMPSTE24;MMP30;PAPPAA;PHEX;ADAMTS15 |
| metallopeptidase activity | ADAMTSL1;ADAM9;ADAM10;ADAMTS5;ADAM23;ADAMTS9;ADAM17;MMP13A;CLCA3 |
| zinc ion binding | ZNF638;RBM14B;RPS29;NR1I3;RNF144AA;TRIM10;NR4A1;CNBPA;NR1H3 |
ADAM21 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ADAM21 here. Most of them are supplied by our site. Hope this information will be useful for your research of ADAM21.
- Q&As
- Reviews
Q&As (5)
Ask a questionADAM21 is abundantly expressed in testicular somatic cells.
The current study demonstrates that male mice deficient in Adam21 are normally fertile.
ADAM21 knockdown inhibits HCC cell proliferation, migration, and invasion and induces cell-cycle arrest and apoptosis.
ADAM20 and ADAM9 have the highest homology to ADAM21.
ADAM21 applied in the study of hepatocellular carcinoma.
Customer Reviews (3)
Write a reviewThe products provided by your company are of good value and quality, and it is a satisfactory shopping experience!
The ADAM21 protein purchased was suitable for WB experiments and the experiments went very well and satisfactory results were obtained.
The technician suggested modifications to my experimental protocol to make my experiment go smoothly.
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