ADAM23
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Official Full Name
ADAM metallopeptidase domain 23
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Overview
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This gene is highly expressed in the brain and may function as an integrin ligand in the brain. -
Synonyms
ADAM23; ADAM metallopeptidase domain 23; a disintegrin and metalloproteinase domain 23; disintegrin and metalloproteinase domain-containing protein 23; MDC3; MDC-3; metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3;
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
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Human | ADAM23-1025H | Active Recombinant Human ADAM23 Protein, His-tagged | CHO | His | Ser60-His585 | |
Human | ADAM23-2479H | Recombinant Human ADAM23 protein(621-710 aa), C-His-tagged | E. coli | C-His | 621-710 aa | |
Homo sapiens (Human) | RFL-10351HF | Recombinant Full Length Human Disintegrin And Metalloproteinase Domain-Containing Protein 23(Adam23) Protein, His-Tagged | E.coli expression system | His | Full Length of Mature Protein (287-832) | |
Chicken | ADAM23-3916C | Recombinant Chicken ADAM23 | Mammalian Cell | His |
- Involved Pathway
- Protein Function
- Interacting Protein
- ADAM23 Related Research Area
ADAM23 involved in several pathways and played different roles in them. We selected most pathways ADAM23 participated on our site, such as Developmental Biology, LGI-ADAM interactions, which may be useful for your reference. Also, other proteins which involved in the same pathway with ADAM23 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Developmental Biology | DUSP10;EFNB3B;FGF10B;DUSP9;MYL9;GDF1;COL9A3;AP2A1;CHL1 |
LGI-ADAM interactions | CACNG8A;LGI2A;LGI1B;LGI3;LGI4;STX1B;LGI1A;LGI1;LGI2 |
ADAM23 has several biochemical functions, for example, integrin binding, metalloendopeptidase activity, metallopeptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ADAM23 itself. We selected most functions ADAM23 had, and list some proteins which have the same functions with ADAM23. You can find most of the proteins on our site.
Function | Related Protein |
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integrin binding | ECM2;TIMP2;CYR61L1;COL4A3;TLN1;MMP14;ADAM25;EGFL6;THBS1 |
metalloendopeptidase activity | HE1A;MMP14A;ECE2;ADAM9;YME1L1B;NRD1B;MMP20;MMP10;MME |
metallopeptidase activity | BRCC3;XPNPEP2;AQPEP;DPP3;HE2;MYSM1;ANPEPB;ADAMTS15A;ADAMTS4 |
protein binding | SUV39H1;COASY;NPBWR2;LZTFL1;KTN1;KLHL38;HEBP2;HOOK3;PDS5A |
zinc ion binding | MMP10;ADAM19;TIMM9;TRIM56;TRIM55A;NR2F6B;VAT1;ZNF276;MLL5 |
ADAM23 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ADAM23 here. Most of them are supplied by our site. Hope this information will be useful for your research of ADAM23.
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- Q&As
- Reviews
Q&As (16)
Ask a questionWe can add tags according to your requirements, and you can communicate directly with our experts.
ADAM23 protein participates in this promotion.
ADAM23 is involved in fertilization, neurogenesis, myoblastogenesis, cell migration, inflammatory response and tumor formation.
ADAM23 is predominantly expressed in brain tissue, weakly expressed in the heart, and predominantly expressed by neuronal cells.
Tags can be customized according to your needs.
ADAM23 interacts with integrin αvβ3.
ADAM11, ADAM22 and ADAM23 have the highest homology.
Yes, we provide a variety of protein expression systems for you to choose from, such as bacterial expression systems, baculovirus-insect cell expression systems, cell-free in vitro protein expression systems, mammalian expression systems, yeast expression systems.
Yes, we can remove the GST label according to your needs.
Yes, we can customize the protein with the corresponding purity according to your needs.
The delivery cycle of custom-made recombinant proteins is between 5-9 weeks.
Yes, if you have this need, you can communicate with our experts.
Yes, we will customize the production of recombinant proteins according to your needs.
This needs to be selected according to your specific research purpose and research situation, and our experts can help you.
ADAM23 can also be used for pancreatic and gastric cancer as well as brain tumor research.
Signal peptide, Prodomain, metalloprotease domain, disintegrin domain, cysteine-richregion, epidermal growth factor (EGF) -like domain, transmembrane domain and cytoplasmic domain.
Customer Reviews (5)
Write a reviewCustomer service was patient, prompt and accurate in answering my queries.
The proteins accepted were of very high purity and were put into experiments with satisfactory results.
Prompt delivery, which helped me to obtain satisfactory experimental results in a short time.
The technician provided a lot of professional advice and helped me a lot during the ELISA.
I purchased this protein for western blot and the band was clear.
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