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ADAM23

  • Official Full Name

    ADAM metallopeptidase domain 23

  • Overview

    This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This gene is highly expressed in the brain and may function as an integrin ligand in the brain.
  • Synonyms

    ADAM23; ADAM metallopeptidase domain 23; a disintegrin and metalloproteinase domain 23; disintegrin and metalloproteinase domain-containing protein 23; MDC3; MDC-3; metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3;
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human ADAM23-1025H Active Recombinant Human ADAM23 Protein, His-tagged CHO His Ser60-His585
Human ADAM23-2479H Recombinant Human ADAM23 protein(621-710 aa), C-His-tagged E. coli C-His 621-710 aa
Homo sapiens (Human) RFL-10351HF Recombinant Full Length Human Disintegrin And Metalloproteinase Domain-Containing Protein 23(Adam23) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (287-832)
Chicken ADAM23-3916C Recombinant Chicken ADAM23 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • ADAM23 Related Research Area

ADAM23 involved in several pathways and played different roles in them. We selected most pathways ADAM23 participated on our site, such as Developmental Biology, LGI-ADAM interactions, which may be useful for your reference. Also, other proteins which involved in the same pathway with ADAM23 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Developmental BiologyDUSP10;EFNB3B;FGF10B;DUSP9;MYL9;GDF1;COL9A3;AP2A1;CHL1
LGI-ADAM interactionsCACNG8A;LGI2A;LGI1B;LGI3;LGI4;STX1B;LGI1A;LGI1;LGI2

ADAM23 has several biochemical functions, for example, integrin binding, metalloendopeptidase activity, metallopeptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ADAM23 itself. We selected most functions ADAM23 had, and list some proteins which have the same functions with ADAM23. You can find most of the proteins on our site.

Function Related Protein
integrin bindingECM2;TIMP2;CYR61L1;COL4A3;TLN1;MMP14;ADAM25;EGFL6;THBS1
metalloendopeptidase activityHE1A;MMP14A;ECE2;ADAM9;YME1L1B;NRD1B;MMP20;MMP10;MME
metallopeptidase activityBRCC3;XPNPEP2;AQPEP;DPP3;HE2;MYSM1;ANPEPB;ADAMTS15A;ADAMTS4
protein bindingSUV39H1;COASY;NPBWR2;LZTFL1;KTN1;KLHL38;HEBP2;HOOK3;PDS5A
zinc ion bindingMMP10;ADAM19;TIMM9;TRIM56;TRIM55A;NR2F6B;VAT1;ZNF276;MLL5

ADAM23 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ADAM23 here. Most of them are supplied by our site. Hope this information will be useful for your research of ADAM23.

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  • Q&As
  • Reviews

Q&As (16)

Ask a question
I want to buy adam23 with other tags, is it available? 02/18/2022

We can add tags according to your requirements, and you can communicate directly with our experts.

Does ADAM23 protein participate in this promotional discount? 12/01/2021

ADAM23 protein participates in this promotion.

What physiological and pathological processes is ADAM23 involved in? 11/05/2021

ADAM23 is involved in fertilization, neurogenesis, myoblastogenesis, cell migration, inflammatory response and tumor formation.

In which tissues is ADAM23 highly expressed? 07/01/2021

ADAM23 is predominantly expressed in brain tissue, weakly expressed in the heart, and predominantly expressed by neuronal cells.

The tag of adam23 whose species is human can only be GST? Can other tags be added? 04/11/2021

Tags can be customized according to your needs.

Does ADAM23 bind to integrin αvβ3? 04/03/2021

ADAM23 interacts with integrin αvβ3.

Which proteins in the ADAM family have the highest homology to ADAM23? 11/30/2020

ADAM11, ADAM22 and ADAM23 have the highest homology.

Can the expression system of full-length ADAM23 be chosen? 09/15/2020

Yes, we provide a variety of protein expression systems for you to choose from, such as bacterial expression systems, baculovirus-insect cell expression systems, cell-free in vitro protein expression systems, mammalian expression systems, yeast expression systems.

Can the GST tag of ADAM23 be removed? 09/10/2020

Yes, we can remove the GST label according to your needs.

Can the purity of ADAM23 protein be customized? 08/25/2020

Yes, we can customize the protein with the corresponding purity according to your needs.

If I have customized needs, how long will it take for the adam23 protein to arrive? 07/16/2020

The delivery cycle of custom-made recombinant proteins is between 5-9 weeks.

Is it possible to custom produce ADAM23 protein with higher purity? 03/22/2020

Yes, if you have this need, you can communicate with our experts.

Can you customize the ADAM23 for a specific band? 12/17/2019

Yes, we will customize the production of recombinant proteins according to your needs.

Can you provide some advice on the selection of different ADAM23 products? 12/01/2019

This needs to be selected according to your specific research purpose and research situation, and our experts can help you.

In addition to breast cancer research, what other diseases is ADAM23 currently used to study? 07/08/2019

ADAM23 can also be used for pancreatic and gastric cancer as well as brain tumor research.

What is the structure domain of ADAM23? 03/26/2019

Signal peptide, Prodomain, metalloprotease domain, disintegrin domain, cysteine-richregion, epidermal growth factor (EGF) -like domain, transmembrane domain and cytoplasmic domain.

Customer Reviews (5)

Write a review
Reviews
01/02/2022

    Customer service was patient, prompt and accurate in answering my queries.

    03/10/2021

      The proteins accepted were of very high purity and were put into experiments with satisfactory results.

      03/01/2021

        Prompt delivery, which helped me to obtain satisfactory experimental results in a short time.

        11/07/2020

          The technician provided a lot of professional advice and helped me a lot during the ELISA.

          04/05/2019

            I purchased this protein for western blot and the band was clear.

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