ADAMTS9
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Official Full Name
ADAM metallopeptidase with thrombospondin type 1 motif, 9
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Overview
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. Members of the ADAMTS family have been implicated in the cleavage of proteoglycans, the control of organ shape during development, and the inhibition of angiogenesis. This gene is localized to chromosome 3p14.3-p14.2, an area known to be lost in hereditary renal tumors. [provided by RefSeq, Jul 2008] -
Synonyms
ADAMTS9; ADAM metallopeptidase with thrombospondin type 1 motif, 9; A disintegrin and metalloproteinase with thrombospondin motifs 9; ADAM-TS9; ADAMTS-9; ADAM-TS 9; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 9;
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
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| Human | ADAMTS9-0017H | Recombinant Human ADAMTS9 Protein (Cys1727-Leu1935), N-His-tagged | E.coli | N-His | Cys1727-Leu1935 |
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| Human | ADAMTS9-1218H | Recombinant Human ADAMTS9 protein, His&Myc-tagged | E.coli | His&Myc | 293-643aa |
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| Human | ADAMTS9-1758H | Recombinant Human ADAMTS9 protein, His & T7-tagged | E.coli | His/T7 | Cys1727~Leu1935 (Accession # Q9P2N4) |
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| Zebrafish | ADAMTS9-8214Z | Recombinant Zebrafish ADAMTS9 | Mammalian Cell | His |
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- Involved Pathway
- Protein Function
- Interacting Protein
ADAMTS9 involved in several pathways and played different roles in them. We selected most pathways ADAMTS9 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ADAMTS9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
ADAMTS9 has several biochemical functions, for example, metalloendopeptidase activity, metallopeptidase activity, zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ADAMTS9 itself. We selected most functions ADAMTS9 had, and list some proteins which have the same functions with ADAMTS9. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| metalloendopeptidase activity | ADAM28;UQCRC2;HE2;ADAM21;BMP1;Adam6;ADAMTSL5;MEP1A.1;UQCRC1 |
| metallopeptidase activity | ADAMTS16;ADAM12;ADAMTS7;YME1L1;MMP14B;BMP1;MMP2;C6AST4;ADAM9 |
| zinc ion binding | ZDHHC21;TRIM35-36;PDZRN4;ADAMTS9;ASTL;NR5A1A;NR5A1B;TRIM43A;RP9 |
ADAMTS9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ADAMTS9 here. Most of them are supplied by our site. Hope this information will be useful for your research of ADAMTS9.
- Q&As
- Reviews
Q&As (5)
Ask a questionADAMTS9 is involved in ECM degradation, angiogenesis, tumours, cardiovascular diseases and many other physiological pathological processes.
ADAMTS9 involved in rectal, pancreatic cancer and other diseases.
ADAMTS9 has the highest homology with ADAMTS20.
Loss of ADAMTS9 resulted in shortened cilia and defective sonic hedgehog signaling.
ADAMTS9 is localized near the basal body of primary cilia in the cytoplasm.
Customer Reviews (4)
Write a reviewThe ADAMTS9 proteins purchased from your company is suitable for ELISA.
Patient customer service and detailed answers to my questions.
The quality of the product is high and the price is cheap, it is worth buying again.
The technical expert will follow up on the progress of my experiments and provide constructive advice on the problems that arise in my experiments.
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