AHRRA
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Zebrafish | AHRRA-3471Z | Recombinant Zebrafish AHRRA | Mammalian Cell | His |
|
- Involved Pathway
- Protein Function
- Interacting Protein
AHRRA involved in several pathways and played different roles in them. We selected most pathways AHRRA participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with AHRRA were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
AHRRA has several biochemical functions, for example, DNA binding, protein dimerization activity, transcriptional repressor activity, RNA polymerase II transcription factor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by AHRRA itself. We selected most functions AHRRA had, and list some proteins which have the same functions with AHRRA. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| DNA binding | PRDM12;TCF7L1B;TIGD3;NEUROD4;ZBTB22;ZNF143;RFX3;BACH1A;MLLT10 |
| protein dimerization activity | MITF;HIF1AL2;TFEB;CLOCKB;NEUROG3;ASCL2;MXD3;ID4;AHR1A |
| transcriptional repressor activity, RNA polymerase II transcription factor binding | CREBBP;ELP2;PITX2;EOMES;MLIP;AHRRB;RIMKLB;AHRR;BHLHE40 |
AHRRA has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AHRRA here. Most of them are supplied by our site. Hope this information will be useful for your research of AHRRA.
- Q&As
- Reviews
Q&As (10)
Ask a questionAHRRA participates in regulating the expression of genes involved in xenobiotic metabolism and detoxification pathways, aiding the body in eliminating harmful substances.
AHRRA's role in cellular metabolism can impact its availability, interactions with co-factors, and overall activity, thereby affecting its role in gene regulation and other cellular processes.
Techniques like circular dichroism spectroscopy, nuclear magnetic resonance (NMR), and X-ray crystallography can provide insights into conformational changes in AHRRA induced by ligand binding.
Techniques such as co-immunoprecipitation, yeast two-hybrid assays, and biophysical methods like surface plasmon resonance are employed to study protein-protein interactions involving AHRRA.
Dysregulated AHRRA expression has been associated with various diseases, including cancer, inflammatory disorders, and developmental abnormalities, due to its role in regulating AHR-mediated gene expression.
AHRRA expression can be influenced by various transcription factors and signaling pathways, including those related to AHR activation itself.
AHRRA binds to specific DNA sequences near AHR-responsive genes, recruiting co-repressor complexes that inhibit transcriptional machinery, leading to gene repression.
AHRRA directly interacts with the Aryl Hydrocarbon Receptor, blocking its ability to bind to DNA and activate target genes, thus acting as a transcriptional repressor.
Researchers can use techniques like siRNA-mediated knockdown or gene editing (e.g., CRISPR/Cas9) to manipulate AHRRA expression in cultured cells for functional studies.
AHRRA's repression of AHR-mediated signaling can affect immune cell differentiation and cytokine production, influencing the outcome of immune responses and inflammation.
Customer Reviews (5)
Write a reviewThis protein is like a reliable teammate in the lab – always delivering excellent results.
Thrilled with the results from their recombined protein.
A reliable source for top-notch protein and friendly guidance.
High-quality product with friendly customer assistance.
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