Akr1c21

  • Official Full Name

    aldo-keto reductase family 1, member C21
Cat.# Product name Source (Host) Species Tag Protein Length Price
AKR1C21-1501M Recombinant Mouse AKR1C21 Protein Mammalian Cells Mouse His
AKR1C21-438M Recombinant Mouse AKR1C21 Protein, His (Fc)-Avi-tagged HEK293 Mouse Avi&Fc&His
AKR1C21-438M-B Recombinant Mouse AKR1C21 Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    Akr1c21 involved in several pathways and played different roles in them. We selected most pathways Akr1c21 participated on our site, such as Arachidonic acid metabolism,Bile acid and bile salt metabolism,Glucocorticoid &amp, which may be useful for your reference. Also, other proteins which involved in the same pathway with Akr1c21 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Metabolism AK8,FABP9,SLC25A20,ABHD10,NUDT3,PDK2B,CYP51A1,SPRB,PHOSPHO1,LPA
    Metabolism of lipids and lipoproteins MED18,CTGF,CERS3B,THEM5,MED25,NFYBA,PNPLA8,Agmo,CETP,DECR1
    Arachidonic acid metabolism PLA2G2F,PLA2G4C,PLA2G2A,MAPKAPK2B,CYP2C19,GPX1,AWAT2,GPX7,CBR1L,LTA4H
    Mineralcorticoid Metabolism CYP11B2,CYP21A2,CYP17A1
    amp CYP11B2,CYP17A1,CYP21A2
    Bile acid and bile salt metabolism SLC27A2,CYP7A1,SCP2B,ACOT8,NCOA2,SLC27A5,AKR1C2,CYP27A1,Alb,BRSK2
    Glucocorticoid &amp CYP21A2,CYP17A1,CYP11B2
    RA biosynthesis pathway DHRS3A,RDH10,ALDH8A1,ADH8A,CRABP1B,DHRS4,CRABP1,RDH14,CYP26A1,RDH14B
    Retinoid metabolism and transport APOC2,RBP4,AKR1C4,RBP1,APOA4A,APOA4B.1,LRP12,APOM,APOA4B.2,LRP10

    Protein Function

    Akr1c21 has several biochemical functions, for example, (R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity,(R)-2-hydroxyglutarate dehydrogenase activity,(R)-2-hydroxyisocaproate dehydrogenase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Akr1c21 itself. We selected most functions Akr1c21 had, and list some proteins which have the same functions with Akr1c21. You can find most of the proteins on our site.

    Function Related Protein
    carboxylic acid binding HMGCL,PCK1,GOT1,AKR1C2,GRHPR,HIF1AN
    acetoin dehydrogenase activity SDR42E1,H2-KE6,HSD11B1LA,HSD3B6,HSD3B5,SDR16C6,AKR1C6
    oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor AKR1C4,AKR1C2,CBR1,AKR1C6,DCXR,NDUFS7,AKR1C3,DHRS4
    D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity H2-KE6,SDR42E1,HSD11B1LA,HSD3B5,AKR1C6,SDR16C6,HSD3B6
    L-arabinose 1-dehydrogenase (NADP+) activity SDR16C6,HSD3B5,H2-KE6,AKR1C6,SDR42E1,HSD3B6,HSD11B1LA
    aldo-keto reductase (NADP) activity SDR42E1,KCNAB1,H2-KE6,HSD11B1LA,SPR,AKR1C6,HSD3B5,AKR1C3,AKR1B10,SDR16C6
    (R)-2-hydroxyisocaproate dehydrogenase activity HSD3B6,HSD11B1LA,H2-KE6,SDR42E1,AKR1C6,HSD3B5,SDR16C6
    epoxide dehydrogenase activity SDR42E1,HSD3B6,SDR16C6,AKR1C6,H2-KE6,HSD3B5,HSD11B1LA
    steroid dehydrogenase activity HSD11B1LA,HSD3B5,HSD3B6,AKR1C6,HSD17B11,SDR42E1,H2-KE6,SDR16C6

    Interacting Protein

    Akr1c21 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Akr1c21 here. Most of them are supplied by our site. Hope this information will be useful for your research of Akr1c21.

    Resources

    References

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