Akr1c21

  • Official Full Name

    aldo-keto reductase family 1, member C21
Cat.# Product name Source (Host) Species Tag Protein Length Price
AKR1C21-1501M Recombinant Mouse AKR1C21 Protein Mammalian Cells Mouse His
AKR1C21-438M Recombinant Mouse AKR1C21 Protein, His (Fc)-Avi-tagged HEK293 Mouse Avi&Fc&His
AKR1C21-438M-B Recombinant Mouse AKR1C21 Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    Akr1c21 involved in several pathways and played different roles in them. We selected most pathways Akr1c21 participated on our site, such as Arachidonic acid metabolism,Bile acid and bile salt metabolism,Glucocorticoid &amp, which may be useful for your reference. Also, other proteins which involved in the same pathway with Akr1c21 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Bile acid and bile salt metabolism SLCO1B1,CYP8B2,BRSK2,AKR1C4,SLC27A2A,SLC27A2,SCP2B,NCOA2,AKR1C2,SLC27A5
    RA biosynthesis pathway DHRS9,RDH13,RDH14B,DHRS3A,RDH14,CRABP1,CRABP1A,ADH8B,DHRS3,RDH14A
    Glucocorticoid &amp CYP11B2,CYP17A1,CYP21A2
    amp CYP17A1,CYP11B2,CYP21A2
    Metabolism SLC5A6B,MED19,HIBADHA,NDUFAF5,UPP2,CYP27B1,SLC16A8,GPC5A,BPNT1,SLC4A1A
    Signal Transduction FGFBP1,LRP12,CRHR2,JUPA,NMB,KREMEN1,KEL,PROKR2,CRABP1B,CCNT2B
    Arachidonic acid metabolism CYP2C70,ALOX5B.3,CYP4B1,PTGS2A,PTGS2B,GPX8,PLA2G2A,GGT5,CYP4F14,GPX3
    Mineralcorticoid Metabolism CYP21A2,CYP11B2,CYP17A1
    Metabolism of lipids and lipoproteins BRSK2,COL4A3BP,ACSF3,ECI1,CPNE1,LPA,CYP4B1,GDF1,ARSK,CYP2V1

    Protein Function

    Akr1c21 has several biochemical functions, for example, (R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity,(R)-2-hydroxyglutarate dehydrogenase activity,(R)-2-hydroxyisocaproate dehydrogenase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Akr1c21 itself. We selected most functions Akr1c21 had, and list some proteins which have the same functions with Akr1c21. You can find most of the proteins on our site.

    Function Related Protein
    dihydrotestosterone 17-beta-dehydrogenase activity AKR1C3,HSD11B1LA,HSD3B6,H2-KE6,AKR1C6,HSD3B5,SDR42E1,SDR16C6
    L-arabinose:NADP reductase activity H2-KE6,SDR42E1,SDR16C6,HSD3B6,AKR1C6,HSD11B1LA,HSD3B5
    (R)-2-hydroxyglutarate dehydrogenase activity AKR1C6,HSD3B6,SDR42E1,HSD3B5,H2-KE6,D2HGDH,SDR16C6,HSD11B1LA
    phenylcoumaran benzylic ether reductase activity HSD3B5,SDR42E1,AKR1C6,SDR16C6,HSD3B6,HSD11B1LA,H2-KE6
    carboxylic acid binding HMGCL,HIF1AN,GOT1,AKR1C2,PCK1,GRHPR
    steroid dehydrogenase activity HSD11B1LA,SDR42E1,HSD17B11,HSD3B5,H2-KE6,SDR16C6,HSD3B6,AKR1C6
    isocitrate dehydrogenase activity AKR1C6,HSD11B1LA,H2-KE6,SDR42E1,HSD3B6,HSD3B5,SDR16C6
    3-hydroxymenthone dehydrogenase activity SDR42E1,SDR16C6,HSD3B5,HSD11B1LA,HSD3B6,AKR1C6,H2-KE6
    ketosteroid monooxygenase activity AKR1C2,AKR1C3

    Interacting Protein

    Akr1c21 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Akr1c21 here. Most of them are supplied by our site. Hope this information will be useful for your research of Akr1c21.

    Resources

    References

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