Akr1c21

  • Official Full Name

    aldo-keto reductase family 1, member C21
Cat.# Product name Source (Host) Species Tag Protein Length Price
AKR1C21-1501M Recombinant Mouse AKR1C21 Protein Mammalian Cells Mouse His
AKR1C21-438M Recombinant Mouse AKR1C21 Protein, His (Fc)-Avi-tagged HEK293 Mouse Avi&Fc&His
AKR1C21-438M-B Recombinant Mouse AKR1C21 Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    Akr1c21 involved in several pathways and played different roles in them. We selected most pathways Akr1c21 participated on our site, such as Arachidonic acid metabolism,Bile acid and bile salt metabolism,Glucocorticoid &amp, which may be useful for your reference. Also, other proteins which involved in the same pathway with Akr1c21 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Metabolism of lipids and lipoproteins ARSJ,APOA4A,Agmo,PPM1LB,GLIPR1,CERS3B,ACOT9.1,HSD17B11,MED16,PIK3R6
    Glucocorticoid &amp CYP11B2,CYP21A2,CYP17A1
    Metabolism PCBD1,PTPMT1,AZIN1B,NUDT4A,CYB5R3,NDUFAF3,CYP2B6,CYP3A7,CYP24A1,SIN3B
    Arachidonic acid metabolism DPEP1,FAAH2B,PTGESL,CBR2,CYP4A11,PTGDSB,CYP2P7,CYP2C38,PLA2G4A,ALOX5A
    Retinoid metabolism and transport LRP10,RBP1,BCO2,RBP4,BCO2A,APOA4B.2,APOA4A,AKR1C6,APOA4B.1,LRP12
    Signal Transduction RGS7,ROPN1,ARAP1,DHRS4,TAX1BP1B,SHARPIN,NOG1,GNA13B,SHRPRBCK1R,GUCA1E
    Bile acid and bile salt metabolism SLC27A5,NCOA2,SLC27A2A,CYP8B2,CYP46A1,ACOT8,AKR1C2,CYP7A1,SLC27A2,AKR1C6
    Mineralcorticoid Metabolism CYP21A2,CYP11B2,CYP17A1
    amp CYP17A1,CYP21A2,CYP11B2

    Protein Function

    Akr1c21 has several biochemical functions, for example, (R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity,(R)-2-hydroxyglutarate dehydrogenase activity,(R)-2-hydroxyisocaproate dehydrogenase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Akr1c21 itself. We selected most functions Akr1c21 had, and list some proteins which have the same functions with Akr1c21. You can find most of the proteins on our site.

    Function Related Protein
    mevaldate reductase activity AKR1C6,SDR42E1,HSD11B1LA,HSD3B6,H2-KE6,SDR16C6,HSD3B5
    steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor AKR1C6,SDR16C6,SDR42E1,H2-KE6,HSD3B5,HSD11B1LA,HSD3B6
    isocitrate dehydrogenase activity AKR1C6,HSD3B5,HSD3B6,H2-KE6,SDR16C6,SDR42E1,HSD11B1LA
    3-ketoglucose-reductase activity HSD3B5,HSD11B1LA,H2-KE6,SDR42E1,HSD3B6,AKR1C6,SDR16C6
    ketosteroid monooxygenase activity AKR1C2,AKR1C3
    phenanthrene 9,10-monooxygenase activity MICAL2B,AKR1C3,MICAL2,AKR1C2
    (R)-2-hydroxyisocaproate dehydrogenase activity HSD11B1LA,SDR42E1,HSD3B6,HSD3B5,SDR16C6,AKR1C6,H2-KE6
    5-exo-hydroxycamphor dehydrogenase activity SDR16C6,AKR1C6,HSD3B5,H2-KE6,HSD11B1LA,SDR42E1,HSD3B6
    androsterone dehydrogenase activity AKR1C4,AKR1C3,AKR1C6

    Interacting Protein

    Akr1c21 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Akr1c21 here. Most of them are supplied by our site. Hope this information will be useful for your research of Akr1c21.

    Resources

    References

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