Akr1c21

  • Official Full Name

    aldo-keto reductase family 1, member C21
Cat.# Product name Source (Host) Species Tag Protein Length Price
AKR1C21-1501M Recombinant Mouse AKR1C21 Protein Mammalian Cells Mouse His
AKR1C21-438M Recombinant Mouse AKR1C21 Protein, His (Fc)-Avi-tagged HEK293 Mouse Avi&Fc&His
AKR1C21-438M-B Recombinant Mouse AKR1C21 Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    Akr1c21 involved in several pathways and played different roles in them. We selected most pathways Akr1c21 participated on our site, such as Arachidonic acid metabolism,Bile acid and bile salt metabolism,Glucocorticoid &amp, which may be useful for your reference. Also, other proteins which involved in the same pathway with Akr1c21 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Glucocorticoid &amp CYP17A1,CYP21A2,CYP11B2
    Signal Transduction RLN3A,CRABP2,APLNR,OPN4,RHOU,GPR31B,KREMEN2,ARHGAP9,TAX1BP1B,OR4D2
    RA biosynthesis pathway AKR1C6,RDH10,RDH13,ADH8B,DHRS3A,RDH14,DHRS3,DHRS9,DHRS4,ADH8A
    Metabolism B3GAT2,SLC26A1,Alb,KCNG4,ADSSL1,ISCUB,SULT1C2,CHST9,GNG13A,MED23
    Mineralcorticoid Metabolism CYP17A1,CYP21A2,CYP11B2
    Bile acid and bile salt metabolism NCOA2,SLC27A2A,AKR1C6,SLCO1B1,SLC27A5,BRSK2,ACOT8,CYP46A1,SCP2B,Alb
    Retinoid metabolism and transport LRP10,LRP12,BCO2A,BCO2,APOA4B.2,APOA4A,RBP1,AKR1C4,APOM,APOA4B.1
    Metabolism of lipids and lipoproteins SPTLC1,CPNE7,MED18,AKR1C6,MED29,APOA5,CYP11B1,ACOT10,LMF1,STARD5
    Arachidonic acid metabolism GPX1A,CYP4F2,CYP4B1,FAAH2A,PTGES2,CYP2P6,GPX5,AWAT1,CYP1B1,PTGIS

    Protein Function

    Akr1c21 has several biochemical functions, for example, (R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity,(R)-2-hydroxyglutarate dehydrogenase activity,(R)-2-hydroxyisocaproate dehydrogenase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Akr1c21 itself. We selected most functions Akr1c21 had, and list some proteins which have the same functions with Akr1c21. You can find most of the proteins on our site.

    Function Related Protein
    oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor AKR1C6,NDUFS7,AKR1C3,DHRS4,CBR1,DCXR,AKR1C4,AKR1C2
    5-exo-hydroxycamphor dehydrogenase activity H2-KE6,SDR42E1,HSD11B1LA,AKR1C6,HSD3B6,SDR16C6,HSD3B5
    2-hydroxytetrahydrofuran dehydrogenase activity SDR16C6,SDR42E1,HSD3B5,H2-KE6,AKR1C6,HSD3B6,HSD11B1LA
    aldo-keto reductase (NADP) activity HSD11B1LA,AKR1B1,KCNAB1,SDR16C6,HSD3B6,KCNAB2,SDR42E1,CYB5A,SPR,AKR1B10
    3-hydroxymenthone dehydrogenase activity AKR1C6,HSD11B1LA,HSD3B5,H2-KE6,SDR16C6,HSD3B6,SDR42E1
    L-xylulose reductase (NAD+) activity HSD3B6,SDR16C6,HSD3B5,SDR42E1,H2-KE6,HSD11B1LA,AKR1C6
    steroid dehydrogenase activity, acting on the CH-CH group of donors HSD11B1LA,SDR16C6,HSD3B5,HSD3B6,H2-KE6,AKR1C6,SDR42E1
    androsterone dehydrogenase activity AKR1C6,AKR1C3,AKR1C4
    phenanthrene 9,10-monooxygenase activity AKR1C2,MICAL2B,AKR1C3,MICAL2

    Interacting Protein

    Akr1c21 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Akr1c21 here. Most of them are supplied by our site. Hope this information will be useful for your research of Akr1c21.

    Resources

    References

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