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Official Full Name aldo-keto reductase family 1, member C21
    • Species :
    • Mouse
    • Source :
    • Mammalian Cell
    • Tag :
    • His
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Mouse AKR1C21-1501M Recombinant Mouse AKR1C21 Protein Mammalian Cell His

    Akr1c21 involved in several pathways and played different roles in them. We selected most pathways Akr1c21 participated on our site, such as Arachidonic acid metabolism, Bile acid and bile salt metabolism, Glucocorticoid &amp, which may be useful for your reference. Also, other proteins which involved in the same pathway with Akr1c21 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Arachidonic acid metabolism CYP2B6; GPX1A; GGT1A; CYP2C39; CYP4A10; GPX1; ALOX8; CYP4F3; GPX2; CYP2P6
    Bile acid and bile salt metabolism AKR1C6; SLC27A5; SLC27A2; AKR1C21; SLC27A2A; ACOT8; AKR1C2; CYP8B2; CYP7A1; CYP27A1
    Glucocorticoid &amp CYP21A2; CYP17A1; CYP11B2; AKR1C21
    amp CYP21A2; AKR1C21; CYP17A1; CYP11B2
    Mineralcorticoid Metabolism AKR1C21; CYP11B2; CYP17A1; CYP21A2
    Metabolism CTRB1; NFYBA; AGL; MED23; SPTLC1; CA5B; FMODA; CA13; BRSK2; CYP26A1
    Metabolism of lipids and lipoproteins ACOT11B; ECI1; LPA; COQ6; APOA4A; CPNE6; SLCO1B1; SLC25A20; CPT2; APOBB.1
    RA biosynthesis pathway RDH7; ALDH8A1; CRABP1; CRABP1B; RDH13; ADH8A; DHRS4; SDR16C5; RDH10; CYP26A1
    Retinoid metabolism and transport RBP4; AKR1C21; LRP10; APOM; BCO2L; APOA4B.1; CLPS; APOA4B.2; LRP12; RBP2A
    Signal Transduction MYO9B; RTN4; CXCR7B; FST; MKS1; GRK7; PTPRK; WDR35; ARHGAP17A; MLN

    Akr1c21 has several biochemical functions, for example, (R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity, (R)-2-hydroxyglutarate dehydrogenase activity, (R)-2-hydroxyisocaproate dehydrogenase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Akr1c21 itself. We selected most functions Akr1c21 had, and list some proteins which have the same functions with Akr1c21. You can find most of the proteins on our site.

    Function Related Protein
    (R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity H2-KE6; AKR1C6; HSD3B6; SDR42E1; HSD11B1LA; AKR1C21; SDR16C6; HSD3B5
    (R)-2-hydroxyglutarate dehydrogenase activity AKR1C21; AKR1C6; HSD3B5; H2-KE6; SDR42E1; HSD11B1LA; HSD3B6; D2HGDH; SDR16C6
    (R)-2-hydroxyisocaproate dehydrogenase activity SDR42E1; HSD11B1LA; HSD3B6; H2-KE6; AKR1C21; SDR16C6; HSD3B5; AKR1C6
    2-hydroxytetrahydrofuran dehydrogenase activity HSD3B5; HSD11B1LA; SDR16C6; AKR1C21; SDR42E1; H2-KE6; HSD3B6; AKR1C6
    3-hydroxymenthone dehydrogenase activity AKR1C6; SDR42E1; H2-KE6; HSD11B1LA; AKR1C21; HSD3B6; SDR16C6; HSD3B5
    3-ketoglucose-reductase activity HSD11B1LA; HSD3B5; HSD3B6; AKR1C6; AKR1C21; SDR42E1; SDR16C6; H2-KE6
    5-exo-hydroxycamphor dehydrogenase activity AKR1C6; HSD3B6; H2-KE6; AKR1C21; HSD11B1LA; SDR16C6; SDR42E1; HSD3B5
    C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity HSD3B6; HSD11B1LA; SDR42E1; HSD3B5; AKR1C6; H2-KE6; AKR1C21; SDR16C6
    D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity AKR1C6; HSD11B1LA; HSD3B5; AKR1C21; SDR16C6; SDR42E1; H2-KE6; HSD3B6
    D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity SDR42E1; SDR16C6; AKR1C21; HSD3B5; AKR1C6; HSD11B1LA; H2-KE6; HSD3B6
    D-xylose:NADP reductase activity H2-KE6; HSD3B5; AKR1C6; SDR42E1; HSD3B6; HSD11B1LA; AKR1C21; SDR16C6
    L-arabinose 1-dehydrogenase (NADP+) activity AKR1C21; H2-KE6; HSD3B5; AKR1C6; SDR42E1; HSD3B6; SDR16C6; HSD11B1LA
    L-arabinose:NADP reductase activity AKR1C21; HSD3B5; HSD3B6; SDR16C6; HSD11B1LA; SDR42E1; AKR1C6; H2-KE6
    L-xylulose reductase (NAD+) activity AKR1C6; SDR16C6; HSD3B6; H2-KE6; SDR42E1; AKR1C21; HSD3B5; HSD11B1LA
    acetoin dehydrogenase activity HSD11B1LA; HSD3B5; SDR16C6; AKR1C21; SDR42E1; AKR1C6; H2-KE6; HSD3B6
    alditol:NADP+ 1-oxidoreductase activity AKR1B1; AKR1C21; AKR1C2; Akr1b3; AKR7A2; PRKRA; AKR1B8; AKR1A1; AKR1C3; AKR7A5
    aldo-keto reductase (NADP) activity SDR16C6; HSD3B6; CYB5A; AKR1B1; AKR1C4; SDR42E1; SPR; AKR1C3; KCNAB1; KCNAB2
    androsterone dehydrogenase (B-specific) activity AKR1C21
    androsterone dehydrogenase activity AKR1C4; AKR1C21; AKR1C6; AKR1C3
    bile acid binding PLA2G1B; AKR1C21; STARD5; PYGL; FABP6; FABP1; FABP10A; AKR1C2; NR1H4
    carboxylic acid binding AKR1C2; HIF1AN; GOT1; AKR1C21; HMGCL; GRHPR; PCK1
    dihydrotestosterone 17-beta-dehydrogenase activity SDR42E1; H2-KE6; SDR16C6; AKR1C6; AKR1C21; HSD3B5; HSD3B6; HSD11B1LA; AKR1C3
    epoxide dehydrogenase activity HSD11B1LA; SDR42E1; AKR1C6; SDR16C6; HSD3B6; AKR1C21; HSD3B5; H2-KE6
    gluconate dehydrogenase activity HSD3B5; H2-KE6; HSD11B1LA; AKR1C21; SDR42E1; SDR16C6; AKR1C6; HSD3B6
    isocitrate dehydrogenase activity AKR1C6; AKR1C21; SDR42E1; HSD11B1LA; HSD3B5; HSD3B6; SDR16C6; H2-KE6
    ketosteroid monooxygenase activity AKR1C21; AKR1C3; AKR1C2
    mevaldate reductase activity SDR16C6; HSD3B5; HSD11B1LA; AKR1C21; H2-KE6; AKR1C6; HSD3B6; SDR42E1
    oxidoreductase activity SDR39U1; CYP2X8; CMAH; CYP2J6; AKR1A1A; MOSC2; FDFT1; ALDH3A2B; LDHBB; IMPDH1A
    oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor AKR1C4; AKR1C6; DCXR; AKR1C2; CBR1; AKR1C21; AKR1C3; DHRS4; NDUFS7
    phenanthrene 9,10-monooxygenase activity AKR1C2; AKR1C3; AKR1C21; MICAL2; MICAL2B
    phenylcoumaran benzylic ether reductase activity AKR1C6; HSD11B1LA; SDR16C6; H2-KE6; HSD3B5; AKR1C21; HSD3B6; SDR42E1
    steroid dehydrogenase activity AKR1C21; SDR16C6; HSD3B6; AKR1C6; HSD3B5; SDR42E1; HSD11B1LA; H2-KE6; HSD17B11
    steroid dehydrogenase activity, acting on the CH-CH group of donors HSD3B5; H2-KE6; AKR1C6; HSD11B1LA; AKR1C21; SDR42E1; SDR16C6; HSD3B6
    steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor H2-KE6; HSD3B6; SDR16C6; HSD3B5; HSD11B1LA; AKR1C21; SDR42E1; AKR1C6
    trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity AKR1C3; AKR1C21; DHDH; AKR1C2
    very long-chain-3-hydroxyacyl-CoA dehydrogenase activity SDR16C6; AKR1C21; HSD3B6; HSD3B5; H2-KE6; AKR1C6; SDR42E1; HSD11B1LA

    Akr1c21 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Akr1c21 here. Most of them are supplied by our site. Hope this information will be useful for your research of Akr1c21.

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