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Official Full Name aldo-keto reductase family 1, member C21
    • Species :
    • Mouse
    • Source :
    • Mammalian Cell
    • Tag :
    • His
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Mouse AKR1C21-1501M Recombinant Mouse AKR1C21 Protein Mammalian Cell His

    Akr1c21 involved in several pathways and played different roles in them. We selected most pathways Akr1c21 participated on our site, such as Arachidonic acid metabolism, Bile acid and bile salt metabolism, Glucocorticoid &amp, which may be useful for your reference. Also, other proteins which involved in the same pathway with Akr1c21 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Arachidonic acid metabolism GPX7; ALOX15B; GGT5A; PTGR1; GPX1A; FAAH2A; PTGS2B; CBR1; ALOX5; CYP2B6
    Bile acid and bile salt metabolism CYP7A1; CYP46A1; CYP8B2; AKR1C2; SLC27A2A; AKR1C21; SCP2B; SLCO1B1; NCOA2; CYP27A1
    Glucocorticoid &amp AKR1C21; CYP21A2; CYP17A1; CYP11B2
    amp AKR1C21; CYP11B2; CYP21A2; CYP17A1
    Mineralcorticoid Metabolism CYP11B2; CYP17A1; AKR1C21; CYP21A2
    Metabolism PRKRA; SLC52A3; AKR1C21; APOF; SLC6A8; UGT1B1; CPNE1; ACOT10; CLPS; CTRC
    Metabolism of lipids and lipoproteins MED19; CDIPT; CPNE1; ARF3; SACM1LB; DPEP1; CYP46A1; G0S2; CYP4B1; MED29
    RA biosynthesis pathway DHRS4; RDH7; RDH14A; CRABP1B; SDR16C5; ALDH8A1; RDH13; ADH8A; CRABP1; DHRS3
    Retinoid metabolism and transport BCO2; APOA4A; AKR1C21; LRP12; APOA4B.2; CLPS; APOC2; LRP10; RBP1; APOM
    Signal Transduction LRIG1; ARHGAP4; WDR35; DNAL4; ADCYAP1B; NRP2B; LRP12; TRH; DRAP1; ADAM12

    Akr1c21 has several biochemical functions, for example, (R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity, (R)-2-hydroxyglutarate dehydrogenase activity, (R)-2-hydroxyisocaproate dehydrogenase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Akr1c21 itself. We selected most functions Akr1c21 had, and list some proteins which have the same functions with Akr1c21. You can find most of the proteins on our site.

    Function Related Protein
    (R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity AKR1C21; HSD11B1LA; SDR16C6; HSD3B6; AKR1C6; H2-KE6; HSD3B5; SDR42E1
    (R)-2-hydroxyglutarate dehydrogenase activity HSD11B1LA; HSD3B6; SDR42E1; AKR1C21; AKR1C6; D2HGDH; SDR16C6; H2-KE6; HSD3B5
    (R)-2-hydroxyisocaproate dehydrogenase activity AKR1C21; HSD3B5; HSD11B1LA; AKR1C6; H2-KE6; SDR42E1; HSD3B6; SDR16C6
    2-hydroxytetrahydrofuran dehydrogenase activity AKR1C6; HSD3B6; AKR1C21; SDR16C6; H2-KE6; HSD3B5; HSD11B1LA; SDR42E1
    3-hydroxymenthone dehydrogenase activity HSD3B6; AKR1C21; SDR16C6; HSD11B1LA; AKR1C6; H2-KE6; HSD3B5; SDR42E1
    3-ketoglucose-reductase activity SDR16C6; HSD3B6; HSD11B1LA; AKR1C6; HSD3B5; H2-KE6; SDR42E1; AKR1C21
    5-exo-hydroxycamphor dehydrogenase activity AKR1C21; HSD3B6; HSD11B1LA; AKR1C6; SDR42E1; H2-KE6; HSD3B5; SDR16C6
    C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity HSD3B5; AKR1C21; HSD3B6; H2-KE6; AKR1C6; SDR16C6; SDR42E1; HSD11B1LA
    D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity AKR1C6; HSD3B6; H2-KE6; SDR42E1; HSD11B1LA; SDR16C6; HSD3B5; AKR1C21
    D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity HSD3B5; AKR1C6; HSD11B1LA; HSD3B6; H2-KE6; SDR16C6; SDR42E1; AKR1C21
    D-xylose:NADP reductase activity HSD11B1LA; AKR1C6; SDR42E1; AKR1C21; HSD3B6; HSD3B5; SDR16C6; H2-KE6
    L-arabinose 1-dehydrogenase (NADP+) activity HSD11B1LA; AKR1C6; HSD3B6; H2-KE6; SDR16C6; SDR42E1; HSD3B5; AKR1C21
    L-arabinose:NADP reductase activity HSD11B1LA; HSD3B6; H2-KE6; AKR1C6; HSD3B5; SDR42E1; AKR1C21; SDR16C6
    L-xylulose reductase (NAD+) activity AKR1C6; SDR16C6; HSD3B6; HSD11B1LA; SDR42E1; HSD3B5; AKR1C21; H2-KE6
    acetoin dehydrogenase activity HSD11B1LA; SDR42E1; HSD3B6; HSD3B5; H2-KE6; SDR16C6; AKR1C6; AKR1C21
    alditol:NADP+ 1-oxidoreductase activity AKR1B1; AKR1C21; AKR7A5; AKR1C3; AKR1B8; PRKRA; Akr1b3; AKR1A1; ADH4; AKR1B7
    aldo-keto reductase (NADP) activity AKR1C21; AKR1C6; MIOX; AKR1C3; SPR; HSD3B6; CYB5A; SDR16C6; AKR1C4; AKR1B1
    androsterone dehydrogenase (B-specific) activity AKR1C21
    androsterone dehydrogenase activity AKR1C4; AKR1C6; AKR1C21; AKR1C3
    bile acid binding PYGL; FABP10A; NR1H4; FABP1; AKR1C21; AKR1C2; STARD5; FABP6; PLA2G1B
    carboxylic acid binding HIF1AN; AKR1C21; AKR1C2; GRHPR; GOT1; HMGCL; PCK1
    dihydrotestosterone 17-beta-dehydrogenase activity AKR1C6; AKR1C3; SDR16C6; HSD11B1LA; HSD3B6; AKR1C21; H2-KE6; HSD3B5; SDR42E1
    epoxide dehydrogenase activity AKR1C21; SDR16C6; AKR1C6; HSD3B6; H2-KE6; HSD11B1LA; HSD3B5; SDR42E1
    gluconate dehydrogenase activity SDR16C6; HSD11B1LA; H2-KE6; HSD3B5; AKR1C21; HSD3B6; SDR42E1; AKR1C6
    isocitrate dehydrogenase activity SDR16C6; AKR1C6; HSD3B5; HSD3B6; SDR42E1; H2-KE6; HSD11B1LA; AKR1C21
    ketosteroid monooxygenase activity AKR1C2; AKR1C21; AKR1C3
    mevaldate reductase activity HSD3B6; HSD3B5; AKR1C21; SDR42E1; SDR16C6; AKR1C6; HSD11B1LA; H2-KE6
    oxidoreductase activity MSRB1A; GSTO2; GULO; PYCR1A; CYP3A41B; GPX4B; SNCA; GDI1; FAXDC2; CYB561A3A
    oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor CBR1; AKR1C4; AKR1C6; NDUFS7; DHRS4; AKR1C3; AKR1C2; DCXR; AKR1C21
    phenanthrene 9,10-monooxygenase activity AKR1C3; MICAL2; MICAL2B; AKR1C2; AKR1C21
    phenylcoumaran benzylic ether reductase activity AKR1C6; HSD11B1LA; AKR1C21; SDR42E1; HSD3B5; SDR16C6; H2-KE6; HSD3B6
    steroid dehydrogenase activity HSD3B5; HSD11B1LA; AKR1C6; SDR16C6; SDR42E1; HSD3B6; HSD17B11; AKR1C21; H2-KE6
    steroid dehydrogenase activity, acting on the CH-CH group of donors SDR16C6; SDR42E1; HSD11B1LA; HSD3B5; HSD3B6; AKR1C6; H2-KE6; AKR1C21
    steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor SDR16C6; HSD11B1LA; AKR1C21; AKR1C6; SDR42E1; H2-KE6; HSD3B6; HSD3B5
    trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity DHDH; AKR1C3; AKR1C2; AKR1C21
    very long-chain-3-hydroxyacyl-CoA dehydrogenase activity SDR16C6; HSD11B1LA; AKR1C21; HSD3B5; AKR1C6; SDR42E1; HSD3B6; H2-KE6

    Akr1c21 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Akr1c21 here. Most of them are supplied by our site. Hope this information will be useful for your research of Akr1c21.

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