Alox12e
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Official Full Name
arachidonate lipoxygenase, epidermal
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| ALOX12E-1565M | Recombinant Mouse ALOX12E Protein | Mammalian Cells | Mouse | His |
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| ALOX12E-635R | Recombinant Rat ALOX12E Protein | Mammalian Cells | Rat | His |
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| ALOX12E-291R | Recombinant Rat ALOX12E Protein, His (Fc)-Avi-tagged | HEK293 | Rat | Avi&Fc&His |
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| ALOX12E-291R-B | Recombinant Rat ALOX12E Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| ALOX12E-482M | Recombinant Mouse ALOX12E Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | Avi&Fc&His |
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| ALOX12E-482M-B | Recombinant Mouse ALOX12E Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
Alox12e involved in several pathways and played different roles in them. We selected most pathways Alox12e participated on our site, such as Arachidonic acid metabolism,Metabolic pathways,Serotonergic synapse, which may be useful for your reference. Also, other proteins which involved in the same pathway with Alox12e were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Arachidonic acid metabolism | CYP2U1,GPX1A,CYP2J6,CYP2C55,ALOX5,CYP2P6,CYP2AD2,AKR1C3,PTGS2B,ALOX12B |
| Serotonergic synapse | MAOA,MAOB,GNG4,TPH2,GNG13,GNG5,PRKCA,ARAF,ALOX15,PRKCG |
| Inflammatory mediator regulation of TRP channels | PLCG2,HTR2C,CALML3,ACCN4,ALOX12,CYP2C50,PLA2G4A,CALM4,CYP2C37,CYP2C39 |
| Metabolic pathways | NDUFC1,DHRS4L2,CYP4A14,PRIM2,CECR1A,NADKB,ALOX15,GAD1,CYP21A1,HOGA1 |
Protein Function
Alox12e has several biochemical functions, for example, arachidonate 12-lipoxygenase activity,dioxygenase activity,iron ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Alox12e itself. We selected most functions Alox12e had, and list some proteins which have the same functions with Alox12e. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| oxidoreductase activity | ETFA,ADH8A,CYP2C9,RDH8B,AKR1CL1,CYP46A1.1,DHRS13B,MSRB1A,JMJD5,CYP4A12A |
| oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen | ALOX5A,TMLHE,ALOX5B.3,P4HA2,P4HA3,ALOX8,ALOX5B.2,ALOX12,ADOA,BCO2 |
| iron ion binding | TMLHE,PPEF1,CYP1B1,CYP26C1,CYP2E1,CYP11C1,HBA-X,CYP2P8,CYP1A1,ALOX5B.2 |
| dioxygenase activity | JMJD5,KDM5BB,KDM4D,BCO2L,MINA,OGFOD2,OGFOD3,HPDA,KDM4C,PTGS1 |
| arachidonate 12-lipoxygenase activity | ALOX12,ALOX15,ALOX12B |
| metal ion binding | COX5A,HBB-Y,SIAH2L,CD209B,IRF2BP2A,KLF17,VPS29,ZSCAN23,ZNF705B,ZBTB16A |
Interacting Protein
Alox12e has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Alox12e here. Most of them are supplied by our site. Hope this information will be useful for your research of Alox12e.
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