AMBN
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Official Full Name
ameloblastin (enamel matrix protein) -
Overview
This gene encodes the nonamelogenin enamel matrix protein ameloblastin. The encoded protein may be important in enamel matrix formation and mineralization. This gene is located in the calcium-binding phosphoprotein gene cluster on chromosome 4. Mutations in this gene may be associated with dentinogenesis imperfect and autosomal dominant amylogenesis imperfect. -
Synonyms
AMBN;ameloblastin (enamel matrix protein);ameloblastin, enamel matrix protein;ameloblastin;AMBN_HUMAN
Recombinant Proteins
- Mouse
- Rat
- Human
- Mammalian Cells
- E.Coli/Yeast
- In Vitro Cell Free System
- HEK293
- Yeast
- E.coli
- His
- Non
- GST
- Avi
- Fc
Involved Pathway
AMBN involved in several pathways and played different roles in them. We selected most pathways AMBN participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with AMBN were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
AMBN has several biochemical functions, for example, growth factor activity,structural constituent of tooth enamel. Some of the functions are cooperated with other proteins, some of the functions could acted by AMBN itself. We selected most functions AMBN had, and list some proteins which have the same functions with AMBN. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| growth factor activity | NENF,CD320,FGF20A,BMP7,IL10,CTGF,GDF5,BMP5,VEGFA,PDGFC |
| structural constituent of tooth enamel | AMELX,AMELY,STATH,TUFT1 |
Interacting Protein
AMBN has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AMBN here. Most of them are supplied by our site. Hope this information will be useful for your research of AMBN.
Resources
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References
- Kiyoshima, T; Nagata, K; et al. Immunohistochemical expression of thymosin beta 4 in ameloblastomas and odontomas. HISTOLOGY AND HISTOPATHOLOGY 28:775-786(2013).
- Hatakeyama, J; Fukumoto, S; et al. Synergistic Roles of Amelogenin and Ameloblastin. JOURNAL OF DENTAL RESEARCH 88:318-322(2009).
