ARHGEF17

  • Official Full Name

    Rac/Cdc42 guanine nucleotide exchange factor (GEF) 17
  • Synonyms

    ARHGEF17;Rac/Cdc42 guanine nucleotide exchange factor (GEF) 17
Cat.# Product name Source (Host) Species Tag Protein Length Price
ARHGEF17-1892M Recombinant Mouse ARHGEF17 Protein Mammalian Cells Mouse His
ARHGEF17-693M Recombinant Mouse ARHGEF17 Protein, His (Fc)-Avi-tagged HEK293 Mouse Avi&Fc&His
ARHGEF17-693M-B Recombinant Mouse ARHGEF17 Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    ARHGEF17 involved in several pathways and played different roles in them. We selected most pathways ARHGEF17 participated on our site, such as Cell death signalling via NRAGE, NRIF and NADE,G alpha (12/13) signalling events,GPCR downstream signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with ARHGEF17 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    G alpha (12/13) signalling events ARHGEF16,KALRNB,RHOC,PLEKHG2,FGD4A,TRIO,ARHGEF1B,GNA13B,MCF2L,ARHGAP4A
    Signal Transduction RHOT1,METAP1,SKIB,RLBP1,RHOV,SOX4A,RGS20,HEYL,TAGAP1,OR56A1
    Signaling by Rho GTPases NOXO1A,ARHGAP32,GDI2,ARHGAP19,ARHGAP12,RHOT1,DCLRE1B,FAM13B1,KIF14,FGD2
    NRAGE signals death through JNK ARHGEF18,TIAM2,ABR,ARHGAP4,ARHGAP4A,FGD4,ARHGEF9,AKAP13,OBSCN,ARHGEF18A
    Cell death signalling via NRAGE, NRIF and NADE AATF,KALRN,DCLRE1B,ABR,FGD2,ARHGEF3,NET1,AKAP13,ARHGAP4,BCL2L11
    Rho GTPase cycle ARHGAP28,RHOU,RHOJ,ARHGAP17,FGD4,ARHGAP17B,ARHGAP22,ARHGAP15,STARD13,ARHGAP25
    GPCR downstream signaling ARHGEF1B,CALCB,FPR-RS4,PRKCHB,RHOGA,QRFP,OR10A5,CCR3,SSTR5,S1PR3
    Signaling by GPCR ARHGEF1B,ADCYAP1B,PYYA,NMBB,GPR37L1,PPY,TAAR1,EDNRAB,OPN4.1,RAMP2

    Protein Function

    ARHGEF17 has several biochemical functions, for example, Rho guanyl-nucleotide exchange factor activity,guanyl-nucleotide exchange factor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ARHGEF17 itself. We selected most functions ARHGEF17 had, and list some proteins which have the same functions with ARHGEF17. You can find most of the proteins on our site.

    Function Related Protein
    Rho guanyl-nucleotide exchange factor activity DOCK10,PLEKHG2,VAV2,PLEKHG4,BCR,ARHGEF39,ARHGEF33,ARHGEF15,ARHGEF12,RASGRF2B
    guanyl-nucleotide exchange factor activity VAV3,CHRM4,FARP2,ANKRD27,RASGRF2B,ARHGEF7A,RASGEF1C,FGD6,RASGEF1BB,DOCK5

    Interacting Protein

    ARHGEF17 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ARHGEF17 here. Most of them are supplied by our site. Hope this information will be useful for your research of ARHGEF17.

    HLA-A;PTCD3

    Resources

    References

    • Zhao, X; Rotenberg, SA; et al. Phosphorylation of Cdc42 Effector Protein-4 (CEP4) by Protein Kinase C Promotes Motility of Human Breast Cells. JOURNAL OF BIOLOGICAL CHEMISTRY 289:25844-25854(2014).
    • Fang, LT; Lee, S; et al. Comprehensive genomic analyses of a metastatic colon cancer to the lung by whole exome sequencing and gene expression analysis. INTERNATIONAL JOURNAL OF ONCOLOGY 44:211-221(2014).

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