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Official Full Name Rho guanine nucleotide exchange factor (GEF) 28
Background This gene encodes a member of the Rho guanine nucleotide exchange factor family. The encoded protein interacts with low molecular weight neurofilament mRNA and may be involved in the formation of amyotrophic lateral sclerosis neurofilament aggregates. Alternate splicing results in multiple transcript variants.
Synonyms ARHGEF28; RIP2; RGNEF; p190RHOGEF; Rho guanine nucleotide exchange factor (GEF) 28; rho guanine nucleotide exchange factor 28; p190-RhoGEF; Rho interacting protein 2; rho-guanine nucleotide exchange factor; 190 kDa guanine nucleotide exchange factor
    • Type:
    • Species :
    • Human
    • Source :
    • HEK293
    • Tag :
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ARHGEF28-540HCL Recombinant Human ARHGEF28 lysate HEK293 N/A

    arhgef28 involved in several pathways and played different roles in them. We selected most pathways arhgef28 participated on our site, such as Axon guidance, Developmental Biology, EPH-Ephrin signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with arhgef28 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Developmental Biology EFNA3B; SPRED1; EFNB1; INSM1B; KCNQ3; DNM1; CACNG2; SALL4; ITSN1; NR5A1
    EPH-Ephrin signaling EPHB4A; MYL9; EFNB3B; ACTR2B; EFNB2A; ARPC1A; EPHB3A; AP2A2; KALRN; CFL1
    EPHB-mediated forward signaling ITSN1; ARPC2; KALRNB; EFNB3; ACTR2; EFNB2; ARPC1A; EPHB3A; ACTR3; EFNB1
    Regulation of RhoA activity ARHGAP9; ARHGEF25; PLEKHG6; NET1; MCF2L; ARAP1; OBSCN; ARHGEF28; ARHGEF10; DEF6
    Signaling events mediated by focal adhesion kinase KLF8; ARHGEF28; ARHGAP26; ACTA1; BMX

    arhgef28 has several biochemical functions, for example, RNA binding, Rho guanyl-nucleotide exchange factor activity, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by arhgef28 itself. We selected most functions arhgef28 had, and list some proteins which have the same functions with arhgef28. You can find most of the proteins on our site.

    Function Related Protein
    RNA binding CSDC2; RDBP; PKZ; RPL31; U2AF2A; RAVER2; SETD1B; MRPL12; KIAA0907; DIS3L
    Rho guanyl-nucleotide exchange factor activity ARHGEF9B; ARHGEF33; DCLRE1B; ARHGEF17; DOCK11; ARHGEF7; ARHGEF10; PLEKHG5; DNMBP; FGD4A
    metal ion binding POGZA; CFI; GTF2E1; ITGAL; ZNF718; HINFP; TAX1BP1B; ZFP64; CYP19A1A; ZFYVE27

    arhgef28 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with arhgef28 here. Most of them are supplied by our site. Hope this information will be useful for your research of arhgef28.


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