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Official Full Name ankyrin repeat and SOCS box containing 4
Background The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Multiple alternatively spliced transcript variants have been described for this gene but some of the full length sequences are not known.
Synonyms ASB4; ankyrin repeat and SOCS box containing 4; ankyrin repeat and SOCS box protein 4; ASB 4; Ankyrin repeat and SOCS box containing protein 4; ankyrin repeat and SOCS box-containing 4; ASB-4
    • Species :
    • Human
    • Mouse
    • Zebrafish
    • Source :
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ASB4-8662HCL Recombinant Human ASB4 293 Cell Lysate HEK293 N/A
    Human ASB4-8663HCL Recombinant Human ASB4 293 Cell Lysate HEK293 N/A
    Human ASB4-893H Recombinant Human ASB4 protein, GST-tagged Wheat Germ GST
    Mouse ASB4-2016M Recombinant Mouse ASB4 Protein Mammalian Cell His
    Zebrafish ASB4-2399Z Recombinant Zebrafish ASB4 Mammalian Cell His

    ASB4 involved in several pathways and played different roles in them. We selected most pathways ASB4 participated on our site, such as Adaptive Immune System, Antigen processing: Ubiquitination &amp, Proteasome degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with ASB4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Adaptive Immune System GAN; SIGLEC9; KIF20A; SIGLEC12; ACTR1B; NRG3; WWP1; KLHL21; RAPGEF3; ICAM4
    Antigen processing: Ubiquitination &amp RNF34; ASB14; WSB1; UBR2; CMTM2A; LRRC41; TRIM9; MKRN1; RNF41; TRIM63
    Proteasome degradation WWP1; RNF220; UBE2L6; RNF25; TRIM63; TRIM41; TRIM11; ASB3; LRR1; RNF4
    Class I MHC mediated antigen processing &amp TRIM41; CTSL1; ASB6; RNF6; LRSAM1; SPSB1; UBE2E3; RNF123; ERAP1; TRIM11
    presentation FBXO27; RNF14; FBXO3; CYBA; KLHL20; MKRN1; SEC24A; CMTM2A; LRR1; LTN1
    Immune System GBP6; GBP2; DUSP3; IFI27; ATG7; KLC3; ACTR1B; DCTN6; IRF4; SOCS3A

    ASB4 has several biochemical functions, for example, ubiquitin protein ligase activity, ubiquitin protein ligase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ASB4 itself. We selected most functions ASB4 had, and list some proteins which have the same functions with ASB4. You can find most of the proteins on our site.

    Function Related Protein
    ubiquitin protein ligase activity UBE2NB; RFWD2; TRIM59; RNF222; TRAIP; RNF34; UBR2; UBE2Z; RBX1; RNF115
    ubiquitin protein ligase binding TMBIM6; FZD5; PER3; CKB; STUB1; MAGEA2; TNFRSF14; GABARAPL2; PARK2; IKBKE

    ASB4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ASB4 here. Most of them are supplied by our site. Hope this information will be useful for your research of ASB4.


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