|Official Full Name||ankyrin repeat and SOCS box containing 4|
|Background||The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Multiple alternatively spliced transcript variants have been described for this gene but some of the full length sequences are not known.|
|Synonyms||ASB4; ankyrin repeat and SOCS box containing 4; ankyrin repeat and SOCS box protein 4; ASB 4; Ankyrin repeat and SOCS box containing protein 4; ankyrin repeat and SOCS box-containing 4; ASB-4|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
ASB4 involved in several pathways and played different roles in them. We selected most pathways ASB4 participated on our site, such as Adaptive Immune System, Antigen processing: Ubiquitination &, Proteasome degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with ASB4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Adaptive Immune System||GAN; SIGLEC9; KIF20A; SIGLEC12; ACTR1B; NRG3; WWP1; KLHL21; RAPGEF3; ICAM4|
|Antigen processing: Ubiquitination &||RNF34; ASB14; WSB1; UBR2; CMTM2A; LRRC41; TRIM9; MKRN1; RNF41; TRIM63|
|Proteasome degradation||WWP1; RNF220; UBE2L6; RNF25; TRIM63; TRIM41; TRIM11; ASB3; LRR1; RNF4|
|Class I MHC mediated antigen processing &||TRIM41; CTSL1; ASB6; RNF6; LRSAM1; SPSB1; UBE2E3; RNF123; ERAP1; TRIM11|
|presentation||FBXO27; RNF14; FBXO3; CYBA; KLHL20; MKRN1; SEC24A; CMTM2A; LRR1; LTN1|
|Immune System||GBP6; GBP2; DUSP3; IFI27; ATG7; KLC3; ACTR1B; DCTN6; IRF4; SOCS3A|
ASB4 has several biochemical functions, for example, ubiquitin protein ligase activity, ubiquitin protein ligase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ASB4 itself. We selected most functions ASB4 had, and list some proteins which have the same functions with ASB4. You can find most of the proteins on our site.
|ubiquitin protein ligase activity||UBE2NB; RFWD2; TRIM59; RNF222; TRAIP; RNF34; UBR2; UBE2Z; RBX1; RNF115|
|ubiquitin protein ligase binding||TMBIM6; FZD5; PER3; CKB; STUB1; MAGEA2; TNFRSF14; GABARAPL2; PARK2; IKBKE|
ASB4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ASB4 here. Most of them are supplied by our site. Hope this information will be useful for your research of ASB4.