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Official Full Name ankyrin repeat and SOCS box containing 7
Background The protein encoded by this gene belongs to a family of ankyrin repeat proteins that, along with four other protein families, contains a C-terminal SOCS box motif. Growing evidence suggests that the SOCS box acts as a bridge between specific substrate-binding domains and the more generic proteins that comprise a large family of E3 ubiquitin protein ligases. In this way, SOCS box containing proteins may regulate protein turnover by targeting proteins for polyubiquination and, therefore, for proteasome-mediated degradation. Two alternative transcripts encoding different isoforms have been described.
Synonyms ASB7; ankyrin repeat and SOCS box containing 7; ankyrin repeat and SOCS box protein 7; Ankyrin repeat and SOCS box containing protein 7; ASB 7; ASB-7; ankyrin repeat and SOCS box-containing 7
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • MYC/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ASB7-3244H Recombinant Human ASB7 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human ASB7-8660HCL Recombinant Human ASB7 293 Cell Lysate HEK293 N/A
    Human ASB7-896H Recombinant Human ASB7 protein, GST-tagged Wheat Germ GST
    Mouse ASB7-2019M Recombinant Mouse ASB7 Protein Mammalian Cell His
    Mouse Asb7-614M Recombinant Mouse Asb7 Protein, MYC/DDK-tagged HEK293T MYC/DDK
    Rhesus Macaque ASB7-423R Recombinant Rhesus monkey ASB7 Protein, His-tagged Mammalian Cell His
    Chicken ASB7-2000C Recombinant Chicken ASB7 Mammalian Cell His
    Zebrafish ASB7-12756Z Recombinant Zebrafish ASB7 Mammalian Cell His

    ASB7 involved in several pathways and played different roles in them. We selected most pathways ASB7 participated on our site, such as Adaptive Immune System, Antigen processing: Ubiquitination &amp, Proteasome degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with ASB7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Adaptive Immune System RNF19B; GAN; CD200; SIGLEC6; DCTN6; KLRB1A; CD160; CXADR; KLRB1F; ERAP1
    Antigen processing: Ubiquitination &amp WSB1; RNF182; ASB13; ASB11; RNF111; LRR1; SH3RF1; ASB8; RBCK1; ATG7
    Proteasome degradation CMTM2A; HUWE1; RNF41; KLHL20; ASB4; TRIM9; TRIM39; RNF220; PJA2; MKRN1
    Class I MHC mediated antigen processing &amp SH3RF1; UBR1; ASB8; RNF41; ASB10; CTSS; RNF138; ASB14; ASB4; CTSL2
    presentation WSB1; FBXO27; CTSL1; WWP1; SH3RF1; HUWE1; UBE2V2; RNF19B; TRIM41; ASB3
    Immune System TRIM17; DCTN6; KIF2C; RAET1E; RNF216; GZMM; KLRB1F; PPAPDC1B; WWP1; CD300C

    ASB7 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ASB7 itself. We selected most functions ASB7 had, and list some proteins which have the same functions with ASB7. You can find most of the proteins on our site.

    Function Related Protein
    protein binding SLC2A1; SNX1; TPI1; TERT; BUC; METTL21C; TXLNG; CTNNBIP1; MRPL9; CD79B

    ASB7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ASB7 here. Most of them are supplied by our site. Hope this information will be useful for your research of ASB7.

    HMBOX1; CCDC136; CUL5; RNF7; ATF4

    Zhang, LF; Zhou, X; et al. Genome Wide Screening of Candidate Genes for Improving Piglet Birth Weight Using High and Low Estimated Breeding Value Populations. INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES 10:236-244(2014).
    Baxter, SS; Carlson, LA; et al. Granulocytic differentiation of HL-60 promyelocytic leukemia cells is associated with increased expression of Cul5. IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL 45:264-274(2009).

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