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ASB7

  • Official Full Name

    ankyrin repeat and SOCS box containing 7

  • Overview

    The protein encoded by this gene belongs to a family of ankyrin repeat proteins that, along with four other protein families, contains a C-terminal SOCS box motif. Growing evidence suggests that the SOCS box acts as a bridge between specific substrate-binding domains and the more generic proteins that comprise a large family of E3 ubiquitin protein ligases. In this way, SOCS box containing proteins may regulate protein turnover by targeting proteins for polyubiquination and, therefore, for proteasome-mediated degradation. Two alternative transcripts encoding different isoforms have been described.
  • Synonyms

    ASB7; ankyrin repeat and SOCS box containing 7; ankyrin repeat and SOCS box protein 7; Ankyrin repeat and SOCS box containing protein 7; ASB 7; ASB-7; ankyrin repeat and SOCS box-containing 7;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rhesus Macaque
  • Zebrafish
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • MYC
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human ASB7-896H Recombinant Human ASB7 protein, GST-tagged Wheat Germ GST
Human ASB7-8660HCL Recombinant Human ASB7 293 Cell Lysate HEK293 N/A
Human ASB7-1361HF Recombinant Full Length Human ASB7 Protein, GST-tagged In Vitro Cell Free System GST 274 amino acids
Human ASB7-3244H Recombinant Human ASB7 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Mouse ASB7-2019M Recombinant Mouse ASB7 Protein Mammalian Cell His
Mouse ASB7-780M Recombinant Mouse ASB7 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Asb7-614M Recombinant Mouse Asb7 Protein, MYC/DDK-tagged HEK293T MYC/DDK
Mouse ASB7-780M-B Recombinant Mouse ASB7 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque ASB7-423R Recombinant Rhesus monkey ASB7 Protein, His-tagged Mammalian Cell His
Rhesus Macaque ASB7-252R-B Recombinant Rhesus Macaque ASB7 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque ASB7-252R Recombinant Rhesus Macaque ASB7 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish ASB7-12756Z Recombinant Zebrafish ASB7 Mammalian Cell His
Chicken ASB7-2000C Recombinant Chicken ASB7 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • ASB7 Related Articles

ASB7 involved in several pathways and played different roles in them. We selected most pathways ASB7 participated on our site, such as Adaptive Immune System, Antigen processing: Ubiquitination &amp, Proteasome degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with ASB7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Adaptive Immune SystemRAP1GAP2B;LILRB2;KIF26A;CHUK;CMTM2A;SIGLEC6;FRS2B;PJA1;TREML1
Antigen processing: Ubiquitination &ampTPP2;FBXO3;TRIM50;RNF6;LRSAM1;UBE2L6;STUB1;LTN1;UBE2V1
Proteasome degradationNPEPPS;ASB8;WSB1;ASB11;ARIH2;UBR1;UBA5;DZIP3;FBXO3
Class I MHC mediated antigen processing &ampWWP1;TRIM39;SEC23A;ARIH2;SPSB2;CD207;UBE2V1;VPRBP;LRSAM1
presentationFBXO3;MKRN1;PJA1;RNF41;RNF34;ASB9;HUWE1;SEC23A;UBA5
Immune SystemTNFRSF13C;NCR3LG1;KPNA5;KPNA4;TRIM6;POLR3H;FBXO3;PELI1;SLAMF6

ASB7 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ASB7 itself. We selected most functions ASB7 had, and list some proteins which have the same functions with ASB7. You can find most of the proteins on our site.

Function Related Protein
protein bindingEIF1AY;LZTS2;MTCH1;PAX9;PCGF2;MPHOSPH8;FLRT3;GMPPA;PILRB

ASB7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ASB7 here. Most of them are supplied by our site. Hope this information will be useful for your research of ASB7.

HMBOX1; CCDC136; CUL5; RNF7; ATF4

Zhang, LF; Zhou, X; et al. Genome Wide Screening of Candidate Genes for Improving Piglet Birth Weight Using High and Low Estimated Breeding Value Populations. INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES 10:236-244(2014).
Baxter, SS; Carlson, LA; et al. Granulocytic differentiation of HL-60 promyelocytic leukemia cells is associated with increased expression of Cul5. IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL 45:264-274(2009).
  • Q&As
  • Reviews

Q&As (4)

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Are there any known therapeutic implications or potential targets involving ASB7? 11/12/2021

Currently, there are no known therapeutic implications specifically related to ASB7. However, exploring its functions and interactions may reveal potential therapeutic targets for certain diseases or conditions.

Are there any known genetic variants or mutations in the ASB7 gene? 03/04/2020

Although ASB7 genetic variants may exist, they have not been extensively studied. Further research is required to identify and understand any potential genetic changes in ASB7.

Is the expression of ASB7 regulated by any specific factors or conditions? 10/29/2018

The specific factors or conditions that regulate ASB7 expression remain largely unknown. Investigating its expression patterns under different conditions could provide insights into its regulatory mechanisms.

Is there any evidence to suggest a role for ASB7 in cellular metabolism or energy homeostasis? 04/25/2018

The involvement of ASB7 in cellular metabolism or energy homeostasis is not well-established. Further research is needed to determine if ASB7 plays a role in these processes.

Customer Reviews (3)

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Reviews
10/04/2016

    Should I encounter any challenges or require technical assistance, the manufacturer provides prompt and knowledgeable support.

    05/29/2016

      Their expertise in protein production and purification ensures the delivery of a high-quality product that consistently performs well in my experiments.

      05/27/2016

        the manufacturer's commitment to quality control and rigorous testing guarantees the reliability and reproducibility of the ASB7 protein, which is essential for obtaining accurate and consistent results.

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