ATAD2

  • Official Full Name

    ATPase family, AAA domain containing 2

  • Overview

    A large family of ATPases has been described, whose key feature is that they share a conserved region of about 220 amino acids that contains an ATP-binding site. The proteins that belong to this family either contain one or two AAA (ATPases Associated with diverse cellular Activities) domains. AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes. The protein encoded by this gene contains two AAA domains, as well as a bromodomain.
  • Synonyms

    ATAD2; ATPase family, AAA domain containing 2; ATPase family AAA domain-containing protein 2; DKFZp667N1320; MGC5254; MGC29843; PRO2000; AAA nuclear coregulator cancer-associated protein; ANCCA; ATAD2_HUMAN; ATPase family AAA domain containing 2; ATPase family AAA domain containing protein 2; MGC131938; MGC142216;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Antibody
  • Human
  • Wheat germ
  • E. coil
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Wheat Germ
  • GST
  • His|Flag
  • N/A
  • N
  • His
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human ATAD2-31H Active Recombinant Human ATAD2, His&Flag-tagged E.coli His/Flag
Human ATAD2-51H Recombinant Human ATAD2 protein, GST-tagged E.coli GST 981-1146
Human ATAD2-8636HCL Recombinant Human ATAD2 293 Cell Lysate HEK293 N/A
Human ATAD2-32HF Recombinant Full Length Human ATAD2 Protein, GST-tagged In Vitro Cell Free System
Human ATAD2-02H Recombinant Human ATAD2 Protein, GST-tagged E. coil GST
Human ATAD2-0128H Recombinant Human ATAD2 Protein (Ser245-Glu396), N-His-tagged E.coli N-His Ser245-Glu396
Wheat germ ATAD2-10H Recombinant Human ATAD2, GST-tagged Wheat Germ N/A
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

ATAD2 involved in several pathways and played different roles in them. We selected most pathways ATAD2 participated on our site, such as Gastric cancer network 2, which may be useful for your reference. Also, other proteins which involved in the same pathway with ATAD2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Gastric cancer network 2LBR;MTDH;TOP2A;SNURF;RAD17;ATAD2;BRIX1;PLAC8;CHTF18

ATAD2 has several biochemical functions, for example, ATP binding, ATPase activity, chromatin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ATAD2 itself. We selected most functions ATAD2 had, and list some proteins which have the same functions with ATAD2. You can find most of the proteins on our site.

Function Related Protein
ATP bindingABCG2A;PAICS;HK2;CARS;MAP2K6;DGKD;UBE2R2;TK1;XRCC5
ATPase activityKIF3CB;KIF4A;PEX6;Abca2;MLH3;VPS4B;ABCG2D;IDE;ABCA9
chromatin bindingERG;GATA3;TP53;MSH6;KDM1A;SOX10;TAF2;NKAP;ZGLP1
histone bindingSNCA;H3F3A;ELP2;HIST1H3C;PKN1;NCL;HIST4H4;HIST1H4E;PRMT7

ATAD2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ATAD2 here. Most of them are supplied by our site. Hope this information will be useful for your research of ATAD2.

SPTBN2; BCAR3; BAG4; ESR1; CASP8; CD247; Naa50; HDAC11

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