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Official Full Name UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
Background This gene encodes a member of the beta-1,3-N-acetylglucosaminyltransferase family. This enzyme is a type II membrane protein. It exhibits strong activity to transfer GlcNAc to glycolipid substrates and is identified as the most likely candidate for lactotriaosylceramide synthase. This enzyme is essential for the expression of Lewis X epitopes on glycolipids.
Synonyms B3GNT5; UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5; B3GN T5; beta3Gn T5; B3GN-T5; Beta 1,3 N acetyglucosaminyltransferase Lc3 synthase; Beta 1,3 N acetylglucosaminyltransferase 5; Beta 1,3-N acetylglucosaminyltransferase bGnT5; Beta-1,3-Gn-T5; Beta3Gn-T5; beta3GnT5; BGnT-5; EC 2.4.1.-; Lactotriaosylceramide synthase; Lc(3)Cer synthase; Lc3 synthase; UDP GlcNAc:betaGal beta 1,3 N acetylglucosaminyltransferase 5; OTTHUMP00000212932; beta-1,3-N-acetylglucosaminyltransferase 5; beta-1,3-N-acetylglucosaminyltransferase bGnT-5; beta 1,3 N-acetyglucosaminyltransferase Lc3 synthase
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human B3GNT5-023H Recombinant Human B3GNT5 protein, GST-tagged Wheat Germ GST
    Human B3GNT5-10106H Recombinant Human B3GNT5, His-tagged E.coli His
    Human B3GNT5-8542HCL Recombinant Human B3GNT5 293 Cell Lysate HEK293 N/A
    Mouse B3GNT5-2243M Recombinant Mouse B3GNT5 Protein Mammalian Cell His
    Rat B3GNT5-917R Recombinant Rat B3GNT5 Protein Mammalian Cell His
    Chicken B3GNT5-3813C Recombinant Chicken B3GNT5 Mammalian Cell His

    b3gnt5 involved in several pathways and played different roles in them. We selected most pathways b3gnt5 participated on our site, such as Glycosphingolipid biosynthesis - lacto and neolacto series, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with b3gnt5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Glycosphingolipid biosynthesis - lacto and neolacto series B3GALT5; FUT6; FUT9A; ST3GAL3B; ST8SIA1; B3GNT3; FUT5; FUT4; B3GALT2; B4GALT3
    Metabolic pathways LTC4S; udp; GALNT1; PLA2G2A; TDO2A; AMY2A2; PIGM; PGLS; COX7B; DAD1

    b3gnt5 has several biochemical functions, for example, beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity, galactosyltransferase activity, lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by b3gnt5 itself. We selected most functions b3gnt5 had, and list some proteins which have the same functions with b3gnt5. You can find most of the proteins on our site.

    Function Related Protein
    beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity B3GNT5
    galactosyltransferase activity GALNTL4; 4931440L10Rik; B3GNT2A; B3GNT9-PS; POC1BL; C1GALT1; B4GALT7; B3GNT2B; POMGNT2; B3GNT5A
    lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity B3GNT5B; B3GNT5; B3GNT5A

    b3gnt5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with b3gnt5 here. Most of them are supplied by our site. Hope this information will be useful for your research of b3gnt5.


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