B3GNT5
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Official Full Name
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
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Overview
This gene encodes a member of the beta-1,3-N-acetylglucosaminyltransferase family. This enzyme is a type II membrane protein. It exhibits strong activity to transfer GlcNAc to glycolipid substrates and is identified as the most likely candidate for lactotriaosylceramide synthase. This enzyme is essential for the expression of Lewis X epitopes on glycolipids. -
Synonyms
B3GNT5; UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5; B3GN T5; beta3Gn T5; B3GN-T5; Beta 1,3 N acetyglucosaminyltransferase Lc3 synthase; Beta 1,3 N acetylglucosaminyltransferase 5; Beta 1,3-N acetylglucosaminyltransferase bGnT5; Beta-1,3-Gn-T5; Beta3Gn-T5; beta3GnT5; BGnT-5; EC 2.4.1.-; Lactotriaosylceramide synthase; Lc(3)Cer synthase; Lc3 synthase; UDP GlcNAc:betaGal beta 1,3 N acetylglucosaminyltransferase 5; OTTHUMP00000212932; beta-1,3-N-acetylglucosaminyltransferase 5; beta-1,3-N-acetylglucosaminyltransferase bGnT-5; beta 1,3 N-acetyglucosaminyltransferase Lc3 synthase;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
- Rat
- E.coli
- HEK293
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- Fc
- Avi
- Non
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | B3GNT5-023H | Recombinant Human B3GNT5 protein, GST-tagged | Wheat Germ | GST |
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| Human | B3GNT5-10106H | Recombinant Human B3GNT5, His-tagged | E.coli | His | C-term-343a.a. | |
| Human | B3GNT5-8542HCL | Recombinant Human B3GNT5 293 Cell Lysate | HEK293 | Non |
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| Human | B3GNT5-1634HF | Recombinant Full Length Human B3GNT5 Protein, GST-tagged | In Vitro Cell Free System | GST | 378 amino acids |
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| Mouse | B3GNT5-2243M | Recombinant Mouse B3GNT5 Protein | Mammalian Cell | His |
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| Mouse | B3GNT5-932M | Recombinant Mouse B3GNT5 Protein, His (Fc)-Avi-tagged | HEK293 | His&Fc&Avi |
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| Mouse | B3GNT5-932M-B | Recombinant Mouse B3GNT5 Protein Pre-coupled Magnetic Beads | HEK293 |
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| Rat | B3GNT5-917R | Recombinant Rat B3GNT5 Protein | Mammalian Cell | His |
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| Rat | B3GNT5-575R | Recombinant Rat B3GNT5 Protein, His (Fc)-Avi-tagged | HEK293 | His&Fc&Avi |
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| Rat | B3GNT5-575R-B | Recombinant Rat B3GNT5 Protein Pre-coupled Magnetic Beads | HEK293 |
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| Chicken | B3GNT5-3813C | Recombinant Chicken B3GNT5 | Mammalian Cell | His |
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- Involved Pathway
- Protein Function
- Interacting Protein
B3GNT5 involved in several pathways and played different roles in them. We selected most pathways B3GNT5 participated on our site, such as Glycosphingolipid biosynthesis - lacto and neolacto series, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with B3GNT5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Glycosphingolipid biosynthesis - lacto and neolacto series | B3GALT1;GCNT2;B3GNT2;B3GNT5A;B3GNT4;ST3GAL4;ST8SIA1;GGTA1;FUT4 |
| Metabolic pathways | HSD17B10;CYP2P7;ATP6V1G3;GAL3ST1A;SAT2B;AMACR;PGM1;GLB1;ALG11 |
B3GNT5 has several biochemical functions, for example, beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity, galactosyltransferase activity, lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by B3GNT5 itself. We selected most functions B3GNT5 had, and list some proteins which have the same functions with B3GNT5. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity | |
| galactosyltransferase activity | B3GNT9-PS;POC1BL;B3GNT4;B3GNT3;B4GALT7;B3GNTL1;B3GNT8;B3GNT5B;DPY19L1 |
| lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity | B3GNT5B;B3GNT5A;B3GNT5 |
B3GNT5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with B3GNT5 here. Most of them are supplied by our site. Hope this information will be useful for your research of B3GNT5.
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