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Official Full Name beaded filament structural protein 2, phakinin
Background Phakinin is a protein that in humans is encoded by the BFSP2 gene. More than 99% of the vertebrate ocular lens consists of terminally differentiated lens fiber cells. Two lens-specific intermediate filament-like proteins, the protein product of this gene (CP49 or phakinin) and filensin (also known as CP115), are expressed only after fiber cell differentiation has begun. Both proteins are found in a structurally unique cytoskeletal element that is referred to as the beaded filament (BF). Mutations in this gene have been associated with juvenile-onset, progressive cataracts and Dowling-Meara epidermolysis bullosa simplex.
Synonyms BFSP2; beaded filament structural protein 2, phakinin; CP47; CP49; LIFL-L; Phakinin; 49 kDa cytoskeletal protein; beaded filament protein CP49; bfps2, Cytoskeletal protein, 49-kD; lens intermediate filament-like light; lens fiber cell beaded filament protein CP 47; lens fiber cell beaded filament protein CP 49; MGC142078; MGC142080; OTTHUMP00000216298; PHAKOSIN
    • Species :
    • Chicken
    • Human
    • Mouse
    • Zebrafish
    • Source :
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Tag :
    • His
    • MYC/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human BFSP2-1494H Recombinant Human BFSP2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human BFSP2-8461HCL Recombinant Human BFSP2 293 Cell Lysate HEK293 N/A
    Mouse BFSP2-2389M Recombinant Mouse BFSP2 Protein Mammalian Cell His
    Mouse Bfsp2-351M Recombinant Mouse Bfsp2 Protein, MYC/DDK-tagged HEK293T MYC/DDK
    Chicken BFSP2-6771C Recombinant Chicken BFSP2 Mammalian Cell His
    Zebrafish BFSP2-1922Z Recombinant Zebrafish BFSP2 Mammalian Cell His

    Bfsp2 involved in several pathways and played different roles in them. We selected most pathways Bfsp2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with Bfsp2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    Bfsp2 has several biochemical functions, for example, protein binding, structural constituent of cytoskeleton, structural constituent of eye lens. Some of the functions are cooperated with other proteins, some of the functions could acted by Bfsp2 itself. We selected most functions Bfsp2 had, and list some proteins which have the same functions with Bfsp2. You can find most of the proteins on our site.

    Function Related Protein
    protein binding RHOA; NFYC; C17orf82; ZBTB24; FAM122A; GSPT2; ADRB3; PDLIM7; SEMA6A; SALL4
    structural constituent of cytoskeleton INA; SYNM; TUBA3C; MAPT; TUBA8L; EPB42; TUBA4L; BICD1; TUBA8L3; TPM1
    structural constituent of eye lens CRYGB; CRYGN2; CRYABB; CRYBA2; CRYGD; BFSP2; LIM2.5; BFSP1; CRYGC; LIM2.3

    Bfsp2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Bfsp2 here. Most of them are supplied by our site. Hope this information will be useful for your research of Bfsp2.


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