BHMT2

  • Official Full Name

    betaine--homocysteine S-methyltransferase 2

  • Overview

    Homocysteine is a sulfur-containing amino acid that plays a crucial role in methylation reactions. Transfer of the methyl group from betaine to homocysteine creates methionine, which donates the methyl group to methylate DNA, proteins, lipids, and other intracellular metabolites. The protein encoded by this gene is one of two methyl transferases that can catalyze the transfer of the methyl group from betaine to homocysteine. Anomalies in homocysteine metabolism have been implicated in disorders ranging from vascular disease to neural tube birth defects such as spina bifida. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
  • Synonyms

    BHMT2; betaine--homocysteine S-methyltransferase 2; Betaine homocysteine S methyltransferase 2; EC 2.1.1.5; FLJ20001; betaine-homocysteine methyltransferase 2;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • C
  • Myc
  • DDK
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human BHMT2-215H Recombinant Human BHMT2 Protein, GST-tagged Wheat Germ GST
Human BHMT2-10224H Recombinant Human BHMT2, His-tagged E.coli His 1-363a.a.
Human BHMT2-179H Recombinant Human BHMT2, His-tagged E.coli His 1-363aa
Human BHMT2-216H Recombinant Human BHMT2 Protein, GST-tagged Wheat Germ GST
Human BHMT2-8457HCL Recombinant Human BHMT2 293 Cell Lysate HEK293 N/A
Human BHMT2-346H Recombinant Human BHMT2 Protein, MYC/DDK-tagged, C13 and N15-labeled HEK293 C-Myc/DDK
Human BHMT2-0758H Recombinant Human BHMT2 Protein (Met1-Phe363), N-His tagged E.coli N-His Met1-Phe363
Human BHMT2-1622HF Recombinant Full Length Human BHMT2 Protein, GST-tagged In Vitro Cell Free System GST 363 amino acids
Mouse BHMT2-2400M Recombinant Mouse BHMT2 Protein Mammalian Cell His
Mouse BHMT2-1030M Recombinant Mouse BHMT2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Bhmt2-1865M Recombinant Mouse Bhmt2 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse BHMT2-1030M-B Recombinant Mouse BHMT2 Protein Pre-coupled Magnetic Beads HEK293
Mouse Bhmt2-317M Recombinant Mouse Bhmt2 Protein, His-tagged E.coli N-His Met1-Ala363
Rat BHMT2-982R Recombinant Rat BHMT2 Protein Mammalian Cell His
Rat BHMT2-640R Recombinant Rat BHMT2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat BHMT2-640R-B Recombinant Rat BHMT2 Protein Pre-coupled Magnetic Beads HEK293
Rat Bhmt2-318R Recombinant Rat Bhmt2 Protein, His-tagged E.coli N-His Met1-Ala363
  • Involved Pathway
  • Protein Function
  • Interacting Protein

BHMT2 involved in several pathways and played different roles in them. We selected most pathways BHMT2 participated on our site, such as L-methionine salvage from L-homocysteine, Metabolism, Metabolism of amino acids and derivatives, which may be useful for your reference. Also, other proteins which involved in the same pathway with BHMT2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
L-methionine salvage from L-homocysteine
MetabolismCYP4B1;PROZA;COX4I1;OAZ1A;DPYS;CYP2W1;CYP24A1;ZDHHC21;CYP2V1
Metabolism of amino acids and derivativesAHCY;OAZ3;OAZ1A;PAOX;AZIN1B;AZIN2;AZIN1A;SLC25A2;CKBA
Sulfur amino acid metabolismCTHL;BHMT2;CDO1
methionine salvage
superpathway of L-methionine salvage and degradation

BHMT2 has several biochemical functions, for example, S-adenosylmethionine-homocysteine S-methyltransferase activity, S-methylmethionine-homocysteine S-methyltransferase activity, NOT betaine-homocysteine S-methyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by BHMT2 itself. We selected most functions BHMT2 had, and list some proteins which have the same functions with BHMT2. You can find most of the proteins on our site.

Function Related Protein
S-adenosylmethionine-homocysteine S-methyltransferase activityBHMT2;BHMT
S-methylmethionine-homocysteine S-methyltransferase activity
NOT betaine-homocysteine S-methyltransferase activity
zinc ion bindingNPLOC4;PHC2B;LIMCH1A;DPYS;RNF34B;PDLIM5B;LIMS1;SKI;ADAM12

BHMT2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BHMT2 here. Most of them are supplied by our site. Hope this information will be useful for your research of BHMT2.

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