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Recombinant Human CA1 Protein, Myc/DDK-tagged, C13 and N15-labeled

Cat.No. : CA1-6515H
Product Overview : CA1 MS Standard C13 and N15-labeled recombinant protein (NP_001729) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
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Description : Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. This CA1 gene is closely linked to the CA2 and CA3 genes on chromosome 8. It encodes a cytosolic protein that is found at the highest level in erythrocytes. Allelic variants of this gene have been described in some populations. Alternative splicing and the use of alternative promoters results in multiple transcript variants.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 28.9 kDa
AA Sequence : MASPDWGYDDKNGPEQWSKLYPIAN GNNQSPVDIKTSETKHDTSLKPISV SYNPATAKEIINVGHSFHVNFEDND NRSVLKGGPFSDSYRLFQFHFHWGS TNEHGSEHTVDGVKYSAELHVAHWN SAKYSSLAEAASKADGLAVIGVLMK VGEANPKLQKVLDALQAIKTKGKRA PFTNFDPSTLLPSSLDFWTYPGSLT HPPLYESVTWIICKESISVSSEQLA QFRSLLSNVEGDNAVPMQHNNRPTQ PLKGRTVRASFTRTRPLEQKLISEE DLAANDILDYKDDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
Gene Name : CA1 carbonic anhydrase I [ Homo sapiens (human) ]
Official Symbol : CA1
Synonyms : CA1; carbonic anhydrase I; carbonic anhydrase 1; Car1; carbonic anhydrase B; carbonic dehydratase; carbonate dehydratase I; CAB; CA-I;
Gene ID : 759
mRNA Refseq : NM_001738
Protein Refseq : NP_001729
MIM : 114800
UniProt ID : P00915

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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How does CA1 protein's phosphorylation change during synaptic stimulation? 04/13/2022

CA1 protein's phosphorylation changes with synaptic stimulation, impacting its function.

What impact do post-translational modifications have on CA1 protein's subcellular localization and synaptic function? 08/22/2021

Post-translational modifications can alter CA1 protein's subcellular localization and synaptic function.

How do epigenetic factors influence CA1 protein's function in memory formation? 07/12/2021

Epigenetic factors influence CA1 protein's function in memory formation via modifications.

What is CA1 protein's specific role in regulating memory processes? 07/27/2018

CA1 protein plays a specific role in memory processes, aiding memory formation.

What is CA1 protein's specific role in regulating synaptic plasticity? 01/07/2018

CA1 protein regulates synaptic plasticity by modulating synaptic strength.

How do genetic factors regulate CA1 protein expression? 10/13/2017

Genetic factors regulate CA1 protein expression, affecting its levels.

Can we develop a high-resolution imaging technique to monitor CA1 protein dynamics within dendritic spines? 10/03/2016

Developing high-resolution imaging techniques for monitoring CA1 protein dynamics is feasible.

Customer Reviews (3)

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Reviews
05/19/2022

    Swift protein purification, expedites our research timelines.

    04/23/2021

      Efficient analysis, aids our understanding of protein function.

      09/17/2020

        Reliable protein assays, critical for our scientific investigations.

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