Recombinant Human CA1 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: CA1-6515H
• Product Overview: CA1 MS Standard C13 and N15-labeled recombinant protein (NP_001729) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. This CA1 gene is closely linked to the CA2 and CA3 genes on chromosome 8. It encodes a cytosolic protein that is found at the highest level in erythrocytes. Allelic variants of this gene have been described in some populations. Alternative splicing and the use of alternative promoters results in multiple transcript variants.
• Source: HEK293
• Species: Human
• Tag: Myc&DDK
• Molecular Mass: 28.9 kDa
• AA Sequence: MASPDWGYDDKNGPEQWSKLYPIAN GNNQSPVDIKTSETKHDTSLKPISV SYNPATAKEIINVGHSFHVNFEDND NRSVLKGGPFSDSYRLFQFHFHWGS TNEHGSEHTVDGVKYSAELHVAHWN SAKYSSLAEAASKADGLAVIGVLMK VGEANPKLQKVLDALQAIKTKGKRA PFTNFDPSTLLPSSLDFWTYPGSLT HPPLYESVTWIICKESISVSSEQLA QFRSLLSNVEGDNAVPMQHNNRPTQ PLKGRTVRASFTRTRPLEQKLISEE DLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: CA1 carbonic anhydrase I [ Homo sapiens (human) ]
• Official Symbol: CA1
• Synonyms: CA1; carbonic anhydrase I; carbonic anhydrase 1; Car1; carbonic anhydrase B; carbonic dehydratase; carbonate dehydratase I; CAB; CA-I
• Gene ID: 759
• mRNA Refseq: NM_001738
• Protein Refseq: NP_001729
• MIM: 114800
• UniProt ID: P00915

Reviews

05/19/2022

Swift protein purification, expedites our research timelines.

04/23/2021

Efficient analysis, aids our understanding of protein function.

09/17/2020

Reliable protein assays, critical for our scientific investigations.

Q&As

How does CA1 protein's phosphorylation change during synaptic stimulation?

CA1 protein's phosphorylation changes with synaptic stimulation, impacting its function.

What impact do post-translational modifications have on CA1 protein's subcellular localization and synaptic function?

Post-translational modifications can alter CA1 protein's subcellular localization and synaptic function.

How do epigenetic factors influence CA1 protein's function in memory formation?

Epigenetic factors influence CA1 protein's function in memory formation via modifications.

What is CA1 protein's specific role in regulating memory processes?

CA1 protein plays a specific role in memory processes, aiding memory formation.

What is CA1 protein's specific role in regulating synaptic plasticity?

CA1 protein regulates synaptic plasticity by modulating synaptic strength.

How do genetic factors regulate CA1 protein expression?

Genetic factors regulate CA1 protein expression, affecting its levels.

Can we develop a high-resolution imaging technique to monitor CA1 protein dynamics within dendritic spines?

Developing high-resolution imaging techniques for monitoring CA1 protein dynamics is feasible.