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Recombinant Rat Car6 protein, His & T7-tagged

Cat.No. : Car6-7841R
Product Overview : Recombinant Rat Car6 aa. (Thr147~Ala275 (Accession # F1LQ08)) fused with N-terminal His & T7 tag was produced in E. coli cells.
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  • Gene Information
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Description : Enzyme that converts bicarbonate to water and CO(2); component of mammalian saliva and milk.
Source : E. coli
Species : Rat
Tag : His & T7
Form : Freeze-dried powder
Molecular Mass : Predicted Molecular Mass: 18.7kDa
Protein length : Thr147~Ala275 (Accession # F1LQ08)
Endotoxin : <1.0EU per 1ug (determined by the LAL method)
Purity : >95%
Characteristic : The isoelectric point is 6.6.
Applications : SDS-PAGE; WB; ELISA; IP
Stability : The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Storage Buffer : Supplied as lyophilized form in PBS, pH7.4, containing 5% sucrose, 0.01% sarcosyl.
Reconstitution : Reconstitute in sterile PBS, pH7.2-pH7.4.
Gene Name : Car6 carbonic anhydrase 6 [ Rattus norvegicus (Norway rat) ]
Official Symbol : Car6
Synonyms : Car6; carbonic anhydrase 6; CA6; carbonic anhydrase VI; gustin
Gene ID : 298657
mRNA Refseq : NM_001134841.1
Protein Refseq : NP_001128313.1
UniProt ID : F1LQ08

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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Are there known genetic mutations in the CA6 gene, and how do they influence protein function? 04/05/2021

Genetic variations might affect CA6's secretion or activity, necessitating functional assays for evaluation.

What is the primary physiological function of CA6? 02/04/2021

CA6 plays a role in the reversible conversion of CO2 to bicarbonate and protons, aiding in pH balance and CO2 transport.

Are there any known proteins or molecules that interact directly with CA6? 05/27/2020

Direct interaction partners for CA6 require further investigation, but it may have specific binding properties due to its unique location.

Where is CA6 predominantly located within the human body? 04/09/2020

CA6 is mainly secreted in saliva and is found in salivary glands.

What are the post-translational modifications identified on CA6? 12/21/2019

Specific post-translational modifications on CA6 can be explored through techniques like mass spectrometry.

How does the enzymatic activity of CA6 compare to other carbonic anhydrase isoforms? 03/31/2018

CA6's activity might be tailored for salivary pH regulation, potentially differing in kinetics from other isoforms.

Are there specific pathological conditions linked with CA6 dysregulation? 06/24/2017

Dysregulation of CA6 might influence oral health, pH regulation, or conditions affecting the salivary glands.

Customer Reviews (3)

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Reviews
12/15/2021

    Outstanding purification techniques, yield top-notch samples.

    09/26/2021

      Fast turnaround time, meets our project deadlines efficiently.

      07/01/2021

        Efficient sample handling, simplifies our daily workloads.

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