Native Human CA6
Cat.No. : | CA6-804H |
Product Overview : | Native Human CA6 was isolated from human milk. |
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Description : | Carbonic anhydrases (CAs) are enzymes which catalyze the reversible hydration of carbon dioxide according to the following reaction: CO2 + H2O ↔ HCO3- + H+. The main function of this protein family is to regulate the acid-base balance, which is of a considerable biological importance. In addition, they participate in several other physiological functions including CO2 and HCO3- transport, bone resorption, production of biological fluids, ureagenesis, gluconeogenesis and lipogenesis. Carbonic anhydrases are metalloenzymes containing a zinc-atom in their active site. The expanding CA gene family includes at least 13 enzymatically active members with different structural and catalytic properties. Purified by CA inhibitor affinity chromatography. |
Source : | Human milk |
Species : | Human |
Form : | 0.1 M Tris-SO4 pH 7.0, 0.4 M NaN3, 1 mM Benzamidine and 20 % glycerol, pH 7.0 |
Molecular Mass : | 35 kDa |
AASequence : | MRALVLLLSLFLLGGQAQHVSDWTY SEGALDEAHWPQHYPACGGQRQSPI NLQRTKVRYNPSLKGLNMTGYETQA GEFPMVNNGHTVQISLPSTMRMTVA DGTVYIAQQMHFHWGGASSEISGSE HTVDGIRHVIEIHIVHYNSKYKSYD IAQDAPDGLAVLAAFVEVNYPENTY YSNFISHLANIKYPGQRTTLTGLDV QDMLPRNLQHYYTYHGSLTTPPCTE NVHWFVLADFVKLSRTQVWKLENSL LDHRNKTIHNDYRRTQPLNHRVVES NFPNQEYTLGSEFQFYLHKIEEILD YLRRALN |
Purity : | > 95 % (SDS-PAGE under reducing conditions) |
Storage : | Store at -80 centigrade, avoid freeze/thaw cycles. |
Tag : | Non |
Gene Name : | CA6 carbonic anhydrase VI [ Homo sapiens ] |
Official Symbol : | CA6 |
Synonyms : | CA-VI; GUSTIN |
Gene ID : | 765 |
mRNA Refseq : | NM_001215.3 |
Protein Refseq : | NP_001206.2 |
MIM : | 114780 |
UniProt ID : | P23280 |
Products Types
◆ Recombinant Protein | ||
CA6-0245H | Recombinant Human CA6 Protein, GST-Tagged | +Inquiry |
CA6-613H | Recombinant Human CA6 protein, His&Myc-tagged | +Inquiry |
Car6-826M | Recombinant Mouse Car6 Protein, MYC/DDK-tagged | +Inquiry |
CA6-2268H | Recombinant Human CA6 Protein, MYC/DDK-tagged | +Inquiry |
CA6-2577H | Recombinant Human CA6 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
CA6-266HCL | Recombinant Human CA6 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Customer Reviews (3)
Write a reviewOutstanding purification techniques, yield top-notch samples.
Fast turnaround time, meets our project deadlines efficiently.
Efficient sample handling, simplifies our daily workloads.
Q&As (7)
Ask a questionGenetic variations might affect CA6's secretion or activity, necessitating functional assays for evaluation.
CA6 plays a role in the reversible conversion of CO2 to bicarbonate and protons, aiding in pH balance and CO2 transport.
Direct interaction partners for CA6 require further investigation, but it may have specific binding properties due to its unique location.
CA6 is mainly secreted in saliva and is found in salivary glands.
Specific post-translational modifications on CA6 can be explored through techniques like mass spectrometry.
CA6's activity might be tailored for salivary pH regulation, potentially differing in kinetics from other isoforms.
Dysregulation of CA6 might influence oral health, pH regulation, or conditions affecting the salivary glands.
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