Recombinant Mouse Car6 Protein, MYC/DDK-tagged

• Cat.No.: Car6-826M
• Product Overview: Purified recombinant protein of full-length mouse carbonic anhydrase 6 (Car6), with C-terminal MYC/DDK tag, was expressed in HEK293T cells.

Specification

• Description: Reversible hydration of carbon dioxide. Its role in saliva is unknown.
• Source: HEK293T
• Species: Mouse
• Tag: Myc&DDK
• Molecular Mass: 36.5 kDa
• Purity: >80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 µg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Car6 carbonic anhydrase 6 [ Mus musculus (house mouse) ]
• Official Symbol: Car6
• Synonyms: Car6; carbonic anhydrase 6; Ca6; DOC1; carbonic anhydrase 6; CA-VI; carbonate dehydratase VI; carbonic anhydrase VI; salivary carbonic anhydrase; secreted carbonic anhydrase; EC 4.2.1.1
• Gene ID: 12353
• mRNA Refseq: NM_009802
• Protein Refseq: NP_033932
• UniProt ID: P18761

Reviews

12/15/2021

Outstanding purification techniques, yield top-notch samples.

09/26/2021

Fast turnaround time, meets our project deadlines efficiently.

07/01/2021

Efficient sample handling, simplifies our daily workloads.

Q&As

Are there known genetic mutations in the CA6 gene, and how do they influence protein function?

Genetic variations might affect CA6's secretion or activity, necessitating functional assays for evaluation.

What is the primary physiological function of CA6?

CA6 plays a role in the reversible conversion of CO2 to bicarbonate and protons, aiding in pH balance and CO2 transport.

Are there any known proteins or molecules that interact directly with CA6?

Direct interaction partners for CA6 require further investigation, but it may have specific binding properties due to its unique location.

Where is CA6 predominantly located within the human body?

CA6 is mainly secreted in saliva and is found in salivary glands.

What are the post-translational modifications identified on CA6?

Specific post-translational modifications on CA6 can be explored through techniques like mass spectrometry.

How does the enzymatic activity of CA6 compare to other carbonic anhydrase isoforms?

CA6's activity might be tailored for salivary pH regulation, potentially differing in kinetics from other isoforms.

Are there specific pathological conditions linked with CA6 dysregulation?

Dysregulation of CA6 might influence oral health, pH regulation, or conditions affecting the salivary glands.