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Recombinant Human CA6 Protein, His&GST-tagged

Cat.No. : CA6-350H
Product Overview : Recombinant Human CA6 Protein (Gln18-Asn308) with N-His&GST tag was expressed in E. coli.
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Description : The protein encoded by this gene is one of several isozymes of carbonic anhydrase. This protein is found only in salivary glands and saliva and protein may play a role in the reversible hydratation of carbon dioxide though its function in saliva is unknown.
Source : E. coli
Species : Human
Tag : N-His&GST
Form : Freeze-dried powder
Molecular Mass : Predicted Molecular Mass: 63.8 kDa
Accurate Molecular Mass: 66 kDa
Protein length : Gln18-Asn308
Purity : > 90%
Applications : Positive Control; Immunogen; SDS-PAGE; WB.
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
Storage Buffer : 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
Reconstitution : Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL. Do not vortex.
Gene Name : CA6 carbonic anhydrase VI [ Homo sapiens (human) ]
Official Symbol : CA6
Synonyms : CA6; carbonic anhydrase VI; carbonic anhydrase 6; carbonate dehydratase VI; salivary carbonic anhydrase; secreted carbonic anhydrase; CA-VI; GUSTIN; MGC21256
Gene ID : 765
mRNA Refseq : NM_001215
Protein Refseq : NP_001206
MIM : 114780
UniProt ID : P23280

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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Are there known genetic mutations in the CA6 gene, and how do they influence protein function? 04/05/2021

Genetic variations might affect CA6's secretion or activity, necessitating functional assays for evaluation.

What is the primary physiological function of CA6? 02/04/2021

CA6 plays a role in the reversible conversion of CO2 to bicarbonate and protons, aiding in pH balance and CO2 transport.

Are there any known proteins or molecules that interact directly with CA6? 05/27/2020

Direct interaction partners for CA6 require further investigation, but it may have specific binding properties due to its unique location.

Where is CA6 predominantly located within the human body? 04/09/2020

CA6 is mainly secreted in saliva and is found in salivary glands.

What are the post-translational modifications identified on CA6? 12/21/2019

Specific post-translational modifications on CA6 can be explored through techniques like mass spectrometry.

How does the enzymatic activity of CA6 compare to other carbonic anhydrase isoforms? 03/31/2018

CA6's activity might be tailored for salivary pH regulation, potentially differing in kinetics from other isoforms.

Are there specific pathological conditions linked with CA6 dysregulation? 06/24/2017

Dysregulation of CA6 might influence oral health, pH regulation, or conditions affecting the salivary glands.

Customer Reviews (3)

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Reviews
12/15/2021

    Outstanding purification techniques, yield top-notch samples.

    09/26/2021

      Fast turnaround time, meets our project deadlines efficiently.

      07/01/2021

        Efficient sample handling, simplifies our daily workloads.

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