cacng1

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cacng1

Official Full Name calcium channel, voltage-dependent, gamma subunit 1
Background Voltage-dependent calcium channels are composed of five subunits. The protein encoded by this gene represents one of these subunits, gamma, and is one of two known gamma subunit proteins. This particular gamma subunit is part of skeletal muscle 1,4-dihydropyridine-sensitive calcium channels and is an integral membrane protein that plays a role in excitation-contraction coupling. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two family members that function as transmembrane AMPA receptor regulatory proteins (TARPs).
Synonyms CACNG1; calcium channel, voltage-dependent, gamma subunit 1; CACNLG; voltage-dependent calcium channel gamma-1 subunit; Dihydropyridine sensitive L type skeletal muscle calcium channel gamma subunit; skeletal muscle calcium channel subunit gamma; CACNLG calcium channel neuronal dihydrpyridine sensitive gamma subunit; Calcium channel L type gamma polypeptide; Calcium channel voltage dependent gamma subunit 1; CCG1_HUMAN; Dihydropyridine sensitive L type skeletal muscle calcium channel subunit gamma; Dihydropyridine-sensitive L-type; fb43f02; fi19g08; L type calcium channel gamma polypeptide; MGC117703; Voltage dependent calcium channel gamma 1 subunit 2; wu:fb43f02; zgc:55364; L-type calcium channel gamma polypeptide; neuronal dihydropyridine-sensitive calcium channel gamma subunit; dihydropyridine-sensitive L-type, skeletal muscle calcium channel subunit gamma
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Source :
    • Mammalian Cell
    • Tag :
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CACNG1-269HCL Recombinant Human CACNG1 cell lysate N/A
    Mouse CACNG1-2623M Recombinant Mouse CACNG1 Protein Mammalian Cell His
    Rat CACNG1-1071R Recombinant Rat CACNG1 Protein Mammalian Cell His
    Chicken CACNG1-5288C Recombinant Chicken CACNG1 Mammalian Cell His

    cacng1 involved in several pathways and played different roles in them. We selected most pathways cacng1 participated on our site, such as MAPK signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, which may be useful for your reference. Also, other proteins which involved in the same pathway with cacng1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    MAPK signaling pathway MECOM; HSPA8; CACNB4A; MAP2K6; HRASA; LRRK2; PPP3CCA; FGF1B; MAP2K4B; CACNB2
    Cardiac muscle contraction COX6C; TPM1; UQCRC2; COX4I2; ATP1A2; COX6B1; ATP1A1B; MYL2B; CACNB3; COX8C
    Adrenergic signaling in cardiomyocytes PPP2R5CB; CACNA2D3; MAPK11; CALML5; ATP1A2; ATP1B1B; TNNC1; PRKACAB; PPP2R2C; CALM2B
    Oxytocin signaling pathway ITPR3; CAMK2A; ACTB; GNAI3; PPP1R12B; GNAO1; GUCY1B3; NFATC3; MYLK4; CAMK2B
    Hypertrophic cardiomyopathy (HCM) ACE; PRKAA2; TGFB3; CACNG4; ITGA8; ACTG1; LMNA; CACNA2D4; DES; ITGA2
    Arrhythmogenic right ventricular cardiomyopathy (ARVC) ITGB1; TCF7; ITGB7; DSC2; Itga10&Itgb1; ACTN4; AASS; ITGA2; CACNA2D3; EMD
    Dilated cardiomyopathy TPM1; PRKACG; MYL3; SGCD; Itga10&Itgb1; ITGA7; PRKACA; ITGA1; GNAS; ITGB7

    cacng1 has several biochemical functions, for example, protein binding, voltage-gated calcium channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by cacng1 itself. We selected most functions cacng1 had, and list some proteins which have the same functions with cacng1. You can find most of the proteins on our site.

    Function Related Protein
    protein binding C22orf23; KRTAP10-5; PKP2; RAD9A; FAM50B; RHEB; PHIP; RFX3; MALSU1; UBE2I
    voltage-gated calcium channel activity CACNG1A; CACNA1D; CACNA2D2; CACNB1; TPC3; NCS1; CACNG2A; NALCN; CACNB2; CACNB2A

    cacng1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with cacng1 here. Most of them are supplied by our site. Hope this information will be useful for your research of cacng1.

    a8ka83_human

    Endoh, T; Sato, D; et al. Galanin inhibits calcium channels via G alpha(i)-protein mediated by GalR1 in rat nucleus tractus solitarius. BRAIN RESEARCH 1229:37-46(2008).
    Endoh, T; et al. Characterization of modulatory effects of postsynaptic metabotropic glutamate receptors on calcium currents in rat nucleus tractus solitarius. BRAIN RESEARCH 1024:212-224(2004).

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