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Official Full Name calcium channel, voltage-dependent, gamma subunit 4
Background The protein encoded by this gene is a type I transmembrane AMPA receptor regulatory protein (TARP). TARPs regulate both trafficking and channel gating of the AMPA receptors. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two family members, a type II TARP and a calcium channel gamma subunit.
Synonyms CACNG4; calcium channel, voltage-dependent, gamma subunit 4; voltage-dependent calcium channel gamma-4 subunit; MGC11138; MGC24983; Neuronal voltage gated calcium channel gamma 4 subunit; Voltage dependent calcium channel gamma 4 subunit; TARP gamma-4; transmembrane AMPAR regulatory protein gamma-4; neuronal voltage-gated calcium channel gamma-4 subunit
    • Species :
    • Chicken
    • Human
    • Rat
    • Source :
    • E.coli
    • Mammalian Cell
    • Tag :
    • GST
    • His
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CACNG4-10644H Recombinant Human CACNG4, GST-tagged E.coli GST
    Rat CACNG4-1073R Recombinant Rat CACNG4 Protein Mammalian Cell His
    Chicken CACNG4-5708C Recombinant Chicken CACNG4 Mammalian Cell His

    CACNG4 involved in several pathways and played different roles in them. We selected most pathways CACNG4 participated on our site, such as MAPK signaling pathway, Cardiac muscle contraction, Adrenergic signaling in cardiomyocytes, which may be useful for your reference. Also, other proteins which involved in the same pathway with CACNG4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    MAPK signaling pathway FGF13; BDNF; MKNK2; PRKACAB; FGF1B; TGFB3; AKT3A; GNG12A; FGF22; LAMTOR3
    Cardiac muscle contraction CACNB1; CACNA2D2; MYL4; COX7B; CACNG2A; CACNB3; ATP1A4; ATP1B3B; TNNT2; ACTC1B
    Adrenergic signaling in cardiomyocytes CACNA2D4; GNA15.1; CACNA1C; CACNA2D1A; CALML3; PLCB3; PPP2R2A; ADCY1A; CALM1; GNAI1
    Oxytocin signaling pathway CALM3; GNAI1; ITPR1; PPP1R12A; NFATC4; CAMKK1; PRKAB1; PLCB1; PRKAA2; RHOA
    Hypertrophic cardiomyopathy (HCM) TPM2; CACNA2D4; PRKAA2; TPM1; ITGB8; ITGB3; CACNA2D3; IL6; ITGA5; ACTB
    Arrhythmogenic right ventricular cardiomyopathy (ARVC) CACNG4; CACNG6; ITGB5; EMD; GJA1; AASS; LMNA; ITGA4; CACNA2D4; ACTN3
    Dilated cardiomyopathy TPM3; TPM4; SGCA; TGFB3; CACNB4; LAMA2; Itga10&Itgb1; LMNA; CACNG1; ITGB1

    CACNG4 has several biochemical functions, for example, channel regulator activity, voltage-gated calcium channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CACNG4 itself. We selected most functions CACNG4 had, and list some proteins which have the same functions with CACNG4. You can find most of the proteins on our site.

    Function Related Protein
    channel regulator activity CACNG2B; CACNG2A; CACNG4; CACNG7; SNF8; SLC9A3R2; CACNG3; CACNG2; CACNG8A; CACNG7A
    voltage-gated calcium channel activity CACNG7; CACNG7A; CACNB4B; CACNA1C; CACNA1SA; CACNA1D; IL1RAPL1; CATSPER3; ATP6V0CB; GAS6

    CACNG4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CACNG4 here. Most of them are supplied by our site. Hope this information will be useful for your research of CACNG4.

    Aoki, Y; Yamada, E; et al. Multiple actions of extracellular ATP and adenosine on calcium currents mediated by various purinoceptors in neurons of nucleus tractus solitarius. NEUROSCIENCE RESEARCH 50:245-255(2004).
    Endoh, T; et al. Characterization of modulatory effects of postsynaptic metabotropic glutamate receptors on calcium currents in rat nucleus tractus solitarius. BRAIN RESEARCH 1024:212-224(2004).

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