CAMK4

  • Official Full Name

    calcium/calmodulin-dependent protein kinase IV

  • Overview

    The product of this gene belongs to the serine/threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. This enzyme is a multifunctional serine/threonine protein kinase with limited tissue distribution, that has been implicated in transcriptional regulation in lymphocytes, neurons and male germ cells.
  • Synonyms

    CAMK4; calcium/calmodulin-dependent protein kinase IV; calcium/calmodulin-dependent protein kinase type IV; brain Ca++ calmodulin dependent protein kinase type IV; calcium/calmodulin dependent protein kinase type IV catalytic chain; CAM kinase IV; CAM kin;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Insect (sf21)
  • Insect Cell
  • Insect Cells
  • Mammalian Cell
  • Sf21
  • Sf9 Insect Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • His|GST
  • Myc
  • DDK
  • MYC
  • Myc|DDK
  • N/A
  • N
  • No tag
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CAMK4-1373H Active Recombinant Human CAMK4, GST-tagged Sf9 Insect Cell GST Full length
Human CAMK4-34HFL Active Recombinant Full Length Human CAMK4 Protein, C-His-tagged Sf21 His Full Length
Human CAMK4-956H Recombinant Human CAMK4 protein, GST-tagged Insect Cells GST Met1-Tyr473
Human CAMK4-1379H Recombinant Human Calcium/Calmodulin-Dependent Protein Kinase IV, His-tagged E.coli His
Human CAMK4-26208TH Recombinant Human CAMK4 N/A
Human CAMK4-268H Recombinant Human CAMK4, GST-tagged, Active Sf9 Insect Cell GST
Human CAMK4-0336H Recombinant Human CAMK4 Protein, GST-Tagged Wheat Germ GST
Human CAMK4-2493H Recombinant Human CAMK4 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human CAMK4-2787HF Recombinant Full Length Human CAMK4 Protein, GST-tagged In Vitro Cell Free System GST 473 amino acids
Human CAMK4-4251H Recombinant Human CAMK4 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human CAMK4-6379HF Active Recombinant Full Length Human CAMK4 Protein, GST-tagged Insect (sf21) GST 1-473(end)
Human CAMK4-0181H Recombinant Human CAMK4 Protein (L2-Y473), Tag Free Insect Cell No tag L2-Y473
Human CAMK4-0182H Recombinant Human CAMK4 Protein (L2-Y473), GST tagged Insect Cell GST L2-Y473
Mouse Camk4-7403M Recombinant Mouse Camk4, His & GST tagged Insect Cell His/GST
Mouse Camk4-477M Recombinant Mouse Camk4, Gly & Pro tagged Insect Cell His
Mouse CAMK4-001MCL Recombinant Mouse CAMK4 cell lysate Insect Cell N/A
Mouse CAMK4-1988M Recombinant Mouse CAMK4 protein Insect Cells N/A Met1-Tyr469
Mouse Camk4-754M Recombinant Mouse Camk4 Protein, MYC/DDK-tagged HEK293T MYC/DDK
Mouse CAMK4-2380M Recombinant Mouse CAMK4 protein(Met1-Tyr469), His&GST-tagged Insect Cells N-His&GST Met1-Tyr469
Rat CAMK4-1106R Recombinant Rat CAMK4 Protein Mammalian Cell His
Rat CAMK4-379R Recombinant Rat CAMK4 Protein (1-474 aa), His-tagged E.coli His 1-474 aa
Rat CAMK4-770R Recombinant Rat CAMK4 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat CAMK4-770R-B Recombinant Rat CAMK4 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish CAMK4-2379Z Recombinant Zebrafish CAMK4 Mammalian Cell His
Chicken CAMK4-3271C Recombinant Chicken CAMK4 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

CAMK4 involved in several pathways and played different roles in them. We selected most pathways CAMK4 participated on our site, such as Calcium signaling pathway, cAMP signaling pathway, Osteoclast differentiation, which may be useful for your reference. Also, other proteins which involved in the same pathway with CAMK4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Calcium signaling pathwayRYR2;ATP2A2;AVPR1B;NOS2;ITPKA;ADRB1;EDNRB2;EDNRA;PRKCA
cAMP signaling pathwayHHIP;ORAI1;GNAI2;VAV3;HTR1B;CREB5;AKT1;PRKACA;PIK3CG
Osteoclast differentiationCSF1R;NFKBIA;PIK3R5;CYLD;IKBKG;FOSB;SIRPB1;TNF;LILRA5
Long-term potentiationGRIA1;CALM2;PLCB2;RAF1;CAMK4;KRAS;ATF4;RPS6KA1;CALM1
Neurotrophin signaling pathwayNTRK2;MAP2K5;NTRK3;FOXO3;GAB1;MAP2K7;BRAF;NFKBIE;IKBKB
Cholinergic synapseGNG10;SLC5A7;PIK3CA;CREB3L3;KRAS;GNG4;CHRNA3;PIK3CB;PRKACB
Oxytocin signaling pathwayCACNA2D4;MAPK7;PRKACG;PPP3CC;PIK3R1;PLCB1;MAP2K5;PRKAG1;CACNA2D1
Aldosterone synthesis and secretionPLCB3;NR4A1;ADCY1;CYP21A2;CREB5;GNAQ;PDE2A;HSD3B1;CAMK2B
AlcoholismHIST1H2AP;GRIN3B;MAOA;HIST3H2A;CALML3;SLC6A3;HIST1H2AD;HIST2H2BE;HIST1H4N

CAMK4 has several biochemical functions, for example, ATP binding, calcium-dependent protein serine/threonine kinase activity, calmodulin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CAMK4 itself. We selected most functions CAMK4 had, and list some proteins which have the same functions with CAMK4. You can find most of the proteins on our site.

Function Related Protein
ATP bindingSYN3;P2RX4B;MKI67;CBWD1;CDC6;AK7;CPS1;CKMT1;MAP2K1
calcium-dependent protein serine/threonine kinase activityMKNK2;MAPKAPK2A;DCX;CAMK4;MKNK2B;MKNK1;CAMK1GA;MKNK2A;MAPKAPK5
calmodulin bindingCAMK1;TRPV1;REM1;MAP6D1;TTN;MYH7;CAMK1GA;MAP2;EPB41
calmodulin-dependent protein kinase activityCAMK2D;MAPKAPK2A;MAPKAPK2;CAMK1;MKNK2B;MYLK3;MKNK1;SLC14A2;CAMK2D1

CAMK4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CAMK4 here. Most of them are supplied by our site. Hope this information will be useful for your research of CAMK4.

HSP90AB1

Research Area

Related articles

Sugiyama, Y; Murao, K; et al. Calcium/calmodulin-dependent protein kinase IV involvement in the pathophysiology of glucotoxicity in rat pancreatic beta-cells. METABOLISM-CLINICAL AND EXPERIMENTAL 60:145-153(2011).
Blanquet, PR; Mariani, J; et al. Temporal assessment of histone H3 phospho-acetylation and casein kinase 2 activation in dentate gyms from ischemic rats. BRAIN RESEARCH 1302:10-20(2009).
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