CBX4

  • Official Full Name

    chromobox homolog 4
  • Synonyms

    CBX4;chromobox homolog 4;chromobox homolog 4 (Drosophila Pc class);E3 SUMO-protein ligase CBX4;hPC2;NBP16;NS5ATP1 binding protein 16;Pc class 2 homolog (Drosophila);PC2;Pc class 2 homolog;polycomb 2 homolog;NS5ATP1-binding protein 16;chromobox
Cat.# Product name Source (Host) Species Tag Protein Length Price
CBX4-10769H Recombinant Human CBX4, GST-tagged E.coli Human GST 1-290a.a.
CBX4-11764Z Recombinant Zebrafish CBX4 Mammalian Cells Zebrafish His
CBX4-6210C Recombinant Chicken CBX4 Mammalian Cells Chicken His
CBX4-7803HCL Recombinant Human CBX4 293 Cell Lysate HEK293 Human Non
CBX4-2780HF Recombinant Full Length Human CBX4 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 290 amino acids

    Involved Pathway

    CBX4 involved in several pathways and played different roles in them. We selected most pathways CBX4 participated on our site, such as C-MYB transcription factor network,Cellular Senescence,Cellular responses to stress, which may be useful for your reference. Also, other proteins which involved in the same pathway with CBX4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    C-MYB transcription factor network COL1A2,MYOD1,YEATS4,LECT2,MYF6,TOM1,PTCRA,SMARCA2,ELANE,CDK6
    Cellular responses to stress HSBP1A,HIST1H1D,NUP50,CHMP4B,WDR45L,BMI1A,KAT5,H3F3B.1,C11orf73,PHC1
    Cellular Senescence BMI1B,AGO3,RING1,PHC2,AGO1,EED,HMGA1B,SCMH1,H1F0,MINK1
    Regulation of retinoblastoma protein BRD2,ATF7,SMARCB1,BGLAP,CKM,ELF1,MYOD1,GSC,AATF
    Post-translational protein modification SPON1A,SENP5,SEC22C,B3GALTL,ADAMTS8,MAN1B1,C8orf84,NAPAA,ST6GAL2B,MUC21
    SUMO E3 ligases SUMOylate target proteins EID3,NSMCE1,RNF2,PHC3,RING1,NSMCE2,SMC6,NSMCE4A,CBX8,PHC2
    Oxidative Stress Induced Senescence CBX8,KDM6B,EED,CBX8B,TNIK,MINK1,BMI1A,SUZ12A,CBX6,RING1
    Metabolism of proteins WDR85,ADAMTS15,NEU3,TRAPPC9,ARSF,CNIH,MGAT4B,CCT6A,TIMM8A,O3far1

    Protein Function

    CBX4 has several biochemical functions, for example, SUMO binding,SUMO transferase activity,chromatin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CBX4 itself. We selected most functions CBX4 had, and list some proteins which have the same functions with CBX4. You can find most of the proteins on our site.

    Function Related Protein
    chromatin binding ERCC6,TFAM,MLH3,C19orf40,TP73,SMARCE1,SFPQ,TADA2B,HMGB1,KDM1A
    SUMO binding RPS3,USP25,USPL1,TDG,TOLLIP,PML,HERC2
    protein binding SLC35F6,RAB11FIP3,TSR2,COMMD8,PTI,TLR4,GJA4,CBFB,AKTIP,ARID3A
    single-stranded RNA binding LSM14A,DLX2,NXF1,LUZP4,TLR7,AGO3,HNRNPF,IFIH1,POLR2G,ANXA1
    ligase activity UFL1,MYLIP,SIAH1A,MARCH10,RNF149,TRIM9,FPGS,RTCD1,MARCH5L,RNF114
    enzyme binding MARCH6,TOP2A,CPSF1,HIST1H2AD,HMGA1-RS1,UGT1A7,EHHADH,CASP2,IL6R,CYP2C19
    transcription regulatory region DNA binding ARID5A,KCNA3,HNF1A,BASP1,PROX1,KLF15,CEBPA,BCOR,REST,CCNT1
    methylated histone binding CHD1,L3MBTL2,SPIN1,CDYL2,GLYR1,RBBP5,CBX7,MSH6,CCDC101,MPHOSPH8
    phosphoprotein binding CACNB2,THRAP3,MS4A2,MID2,TRPV1,RRAGA,SNCA,ARR3,TBK1,LRP11

    Interacting Protein

    CBX4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CBX4 here. Most of them are supplied by our site. Hope this information will be useful for your research of CBX4.

    BMI1;HIF1A

    Resources

    References

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