CBX4

  • Official Full Name

    chromobox homolog 4
  • Synonyms

    CBX4;chromobox homolog 4;chromobox homolog 4 (Drosophila Pc class);E3 SUMO-protein ligase CBX4;hPC2;NBP16;NS5ATP1 binding protein 16;Pc class 2 homolog (Drosophila);PC2;Pc class 2 homolog;polycomb 2 homolog;NS5ATP1-binding protein 16;chromobox
Cat.# Product name Source (Host) Species Tag Protein Length Price
CBX4-10769H Recombinant Human CBX4, GST-tagged E.coli Human GST 1-290a.a.
CBX4-11764Z Recombinant Zebrafish CBX4 Mammalian Cells Zebrafish His
CBX4-6210C Recombinant Chicken CBX4 Mammalian Cells Chicken His
CBX4-7803HCL Recombinant Human CBX4 293 Cell Lysate HEK293 Human Non
CBX4-2780HF Recombinant Full Length Human CBX4 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 290 amino acids

    Involved Pathway

    CBX4 involved in several pathways and played different roles in them. We selected most pathways CBX4 participated on our site, such as C-MYB transcription factor network,Cellular Senescence,Cellular responses to stress, which may be useful for your reference. Also, other proteins which involved in the same pathway with CBX4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Post-translational protein modification WDR85,ADAMTS10,MUC13,MAN1A2,OTOP2,SEC16B,SMC6,DAD1,TRAPPC10,ZNF408
    SUMO E3 ligases SUMOylate target proteins PHC2,NSMCE2,RNF2,PHC3,CBX8,PHC1,SMC5,EID3,RING1,NSMCE4A
    Cellular responses to stress GABARAPL2,HBXIP,UVRAG,HSBP1,ST13,WIPI1,GABARAP,RB1CC1,EHMT2,RRAGB
    C-MYB transcription factor network SLC25A3,MYB,MYOD1,CLTA,CEBPA,CSF1R,ELANE,CDK6,LECT2,PTCRA
    Regulation of retinoblastoma protein AATF,ELF1,SMARCB1,CKM,MYOD1,BRD2,GSC,BGLAP,ATF7
    Metabolism of proteins ADAMTS10,PAPPA2,WIPI1,TRAPPC1,ARSH,LMCD1,TOMM40,IGFBP1B,FBXW4,MPDU1A
    Oxidative Stress Induced Senescence CBX8,TNIK,CBX6,PHC1,CBX6A,CBX8B,SCMH1,SUZ12B,PHC2,MINK1
    Cellular Senescence MOV10,HIST4H4,CDKN2D,BMI1A,CDK6,ACD,HIST2H3C,RBBP4,RBBP7,ERF

    Protein Function

    CBX4 has several biochemical functions, for example, SUMO binding,SUMO transferase activity,chromatin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CBX4 itself. We selected most functions CBX4 had, and list some proteins which have the same functions with CBX4. You can find most of the proteins on our site.

    Function Related Protein
    ligase activity TTLL11,RNF115,TTLL6,TRIML1,TRIM5,HACE1,BIRC7,SIAH1,ACSL1,RNF169
    chromatin binding HMG20B,TDRD3,ZFP143,DNMT1,SMAD4,EP300,DLX3,SMARCD1,TLE4,HMGXB4
    transcription corepressor activity NANOG,HOMEZA,AES,CDX2,TFCP2L1,TBL1Y,HDAC3,AEBP2,RCOR2,MECP2
    transcription regulatory region DNA binding BRCA1,SALL3,GABPB1,ATF4,ATF3,GFI1,ZFP335,TRP53,WT1,NKX3-1
    single-stranded RNA binding EIF2C3,SNRPC,NXF1,AGO3,CBX6,AGO2,LUZP4,TLR8,A1CF,ZFP36
    phosphoprotein binding FKBP4,GPRIN1,PIH1D1,DPYSL3,LYN,SNCA,PKD2,SAG,RRAGA,MID1
    SUMO transferase activity MUL1,NSMCE2,UBE2IB,PIAS3,TOPORS,SUMO1,SUMO3,UBE2IA,SUMO4,UBE2I
    protein binding TCEB3B,GOLGA7,HOXD12,TNS3,GABPB1,GOLGA3,MLH3,FAM184A,STX2,ZNF193
    enzyme binding CA,CASC3,PGR,NPC2,SCNM1-PS,UGT1A1,CREB1,PTPLAD1,GSTM1,PRKCA

    Interacting Protein

    CBX4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CBX4 here. Most of them are supplied by our site. Hope this information will be useful for your research of CBX4.

    BMI1;HIF1A

    Resources

    References

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