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Official Full Name chromobox homolog 4
Synonyms CBX4; chromobox homolog 4; chromobox homolog 4 (Drosophila Pc class); E3 SUMO-protein ligase CBX4; hPC2; NBP16; NS5ATP1 binding protein 16; Pc class 2 homolog (Drosophila); PC2; Pc class 2 homolog; polycomb 2 homolog; NS5ATP1-binding protein 16; chromobox
    • Species :
    • Chicken
    • Human
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CBX4-0482H Recombinant Human CBX4 Protein, GST-Tagged Wheat Germ GST
    Human CBX4-10769H Recombinant Human CBX4, GST-tagged E.coli GST
    Human CBX4-7803HCL Recombinant Human CBX4 293 Cell Lysate HEK293 N/A
    Chicken CBX4-6210C Recombinant Chicken CBX4 Mammalian Cell His
    Zebrafish CBX4-11764Z Recombinant Zebrafish CBX4 Mammalian Cell His

    cbx4 involved in several pathways and played different roles in them. We selected most pathways cbx4 participated on our site, such as C-MYB transcription factor network, Cellular Senescence, Cellular responses to stress, which may be useful for your reference. Also, other proteins which involved in the same pathway with cbx4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    C-MYB transcription factor network ADORA2B; CSF1R; PIAS3; MYOD1; YEATS4; SMARCA2; PPID; SLC25A3; COL1A2; CLTA
    Cellular Senescence EP400; HIST1H1E; IGFBP7; TNIK; CDKN2D; E2F2; CBX8; HIST2H3C; CBX8B; EED
    Cellular responses to stress LAMTOR2; CHMP4C; PRDX2; RRAGB; PHC1; CDKN2B; TERF2; CBX8B; RBBP7; EED
    Metabolism of proteins PHC1; SERP1; ADD1; CTDSP2; NSMCE2; ARSE; CPB2; IGFBP5A; ACE; PCSK2
    Oxidative Stress Induced Senescence MINK1; SCMH1; TNIK; KDM6B; CBX8; CBX6A; SUZ12; BMI1A; PHC1; CBX6
    Post-translational protein modification MAGT1; MPDU1; NAPAB; DAD1; TFG; RING1; DOHH; NAPAA; DNAJC24; LMAN2
    Regulation of retinoblastoma protein MYOD1; SMARCB1; AATF; GSC; ELF1; BGLAP; CKM; BRD2; ATF7; CBX4
    SUMO E3 ligases SUMOylate target proteins CBX8; PHC2; SMC5; EID3; PHC1; NSMCE1; SMC6; PHC3; NSMCE4A; SCMH1

    cbx4 has several biochemical functions, for example, SUMO binding, SUMO transferase activity, chromatin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by cbx4 itself. We selected most functions cbx4 had, and list some proteins which have the same functions with cbx4. You can find most of the proteins on our site.

    Function Related Protein
    SUMO binding USPL1; HERC2; RPS3; USP25; TOLLIP; CBX4; TDG; PML
    SUMO transferase activity TOPORS; PIAS4; SUMO1; SUMO4; PIAS3; UBE2I; CBX4; UBE2IA; NSMCE2; MUL1
    chromatin binding ZMYND11; PPARGC1A; NKX6-1; ARID3A; MED12; SIRT7; PBRM1; ARNTL1B; PHF21A; NR5A2
    enzyme binding PUS7; NCOA1; CTNNBL1; MARCH6; JUN; DNMT3L; ANK1; Il6ra; HAND1; PLSCR1
    ligase activity ARIH1; CNOT4; CBLB; MID2; UBE2L3A; ACSL1; CBX4; RNF170; SYVN1; PIAS2
    methylated histone binding WDR92; LOXL2; CBX7; RAG2; KDM4A; PHF1; MPHOSPH8; MSL3; L3MBTL1; ING1
    phosphoprotein binding DPYSL3; THRAP3; SFN; SNCA; YWHAB; APTX; URI1; RB1; PKD2; RRAGA
    protein binding RAP1GAP; MICALL1; PRRG2; MRPL44; MZT1; RILP; DRG1; NEUROG1; ACTG1; VBP1
    single-stranded RNA binding DLX2; ZFP36; RBMX; DHX58; AGO1; LUZP4; NXF1; CBX4; EIF2C3; PIWIL1
    transcription corepressor activity ELK3; HOMEZ; NSD1; SMYD1; PEX14; TSG101; SOD3; EID1; RCOR2; BHLHE40
    transcription regulatory region DNA binding WT1; TCF7; HOXA13; HHEX; AIRE; KLF2A; NKX3; LEF1; MZF1; RFX6

    cbx4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with cbx4 here. Most of them are supplied by our site. Hope this information will be useful for your research of cbx4.

    BMI1; HIF1A

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