CBX4

  • Official Full Name

    chromobox homolog 4
  • Synonyms

    CBX4;chromobox homolog 4;chromobox homolog 4 (Drosophila Pc class);E3 SUMO-protein ligase CBX4;hPC2;NBP16;NS5ATP1 binding protein 16;Pc class 2 homolog (Drosophila);PC2;Pc class 2 homolog;polycomb 2 homolog;NS5ATP1-binding protein 16;chromobox
Cat.# Product name Source (Host) Species Tag Protein Length Price
CBX4-10769H Recombinant Human CBX4, GST-tagged E.coli Human GST 1-290a.a.
CBX4-11764Z Recombinant Zebrafish CBX4 Mammalian Cells Zebrafish His
CBX4-6210C Recombinant Chicken CBX4 Mammalian Cells Chicken His
CBX4-7803HCL Recombinant Human CBX4 293 Cell Lysate HEK293 Human Non
CBX4-2780HF Recombinant Full Length Human CBX4 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 290 amino acids

    Involved Pathway

    CBX4 involved in several pathways and played different roles in them. We selected most pathways CBX4 participated on our site, such as C-MYB transcription factor network,Cellular Senescence,Cellular responses to stress, which may be useful for your reference. Also, other proteins which involved in the same pathway with CBX4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    C-MYB transcription factor network LECT2,PRTN3,CEBPB,CREBBP,COL1A2,MYF6,GATA1,CDKN1B,PTCRA,CEBPA
    SUMO E3 ligases SUMOylate target proteins PHC3,CBX8,RNF2,PHC2,PHC1,RING1,SMC5,NSMCE4A,NSMCE2,SMC6
    Oxidative Stress Induced Senescence EED,RING1,CBX8A,PHC2,MINK1,BMI1B,CBX8B,SUZ12,SUZ12A,BMI1A
    Regulation of retinoblastoma protein ATF7,BGLAP,ELF1,CKM,AATF,MYOD1,BRD2,SMARCB1,GSC
    Metabolism of proteins MFGE8,TRAPPC3,TRAPPC10,CTDSP2,EIF5A2,SFTPC,EEF1A2,TIMM50,SLC35A1,GRPEL2
    Cellular responses to stress EGLN2,HSPA12B,HIST1H1C,PTGES3,GABARAP,KDM6B,CHMP4C,HSPA7,CBX8,HIST2H3C
    Post-translational protein modification TMED10,THSD7A,SCMH1,MUC20,SEC16B,MPDU1,C8orf84,B3GNT8,MUC12,NEU3
    Cellular Senescence H3F3D,EHMT2,CBX6,KDM6B,POT1A,Txn1,HMGA1B,CDKN2C,POT1,PHC3

    Protein Function

    CBX4 has several biochemical functions, for example, SUMO binding,SUMO transferase activity,chromatin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CBX4 itself. We selected most functions CBX4 had, and list some proteins which have the same functions with CBX4. You can find most of the proteins on our site.

    Function Related Protein
    protein binding ISYNA1,PMAIP1,PAIP1,TJAP1,RNMT,STK10,CRMP1,DTNB,ANKRD54,MRAP2
    SUMO binding TOLLIP,PML,HERC2,TDG,RPS3,USPL1,USP25
    transcription corepressor activity LIMD1,TFCP2L1,TAF9B,HDAC5,MXD1,LHX9,HDAC7,NAB2,JUB,ZHX2
    SUMO transferase activity SUMO4,UBE2IA,SUMO3,UBE2I,PIAS4,TOPORS,PIAS3,NSMCE2,MUL1,SUMO1
    phosphoprotein binding YWHAB,CACNB2,CSNK1D,SERPINB1A,SNCA,TRPV1,YWHAE,THRAP3,PITX2,RB1
    transcription regulatory region DNA binding GRHL1,CTNNB1,GATA3,ATMIN,HNRNPL,CTCFL,BCOR,HINFP,TAF2,STAT3
    ligase activity TRIP12,RAG1,STUB1,MIB1,MARCH4,HACE1,PPIL2,HERC3,TRIM63,PET112L
    methylated histone binding ING5,PHF2,RBBP5,FAM156A,LRWD1,GLYR1,UHRF1,MPHOSPH8,JHDM1D,SUZ12
    chromatin binding OVOL2,HMGB2B,ATAD2B,CREB3L1,TFAP2A,POU1F1,NFATC2,TBL1Y,GLI3,CSNK2B

    Interacting Protein

    CBX4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CBX4 here. Most of them are supplied by our site. Hope this information will be useful for your research of CBX4.

    BMI1;HIF1A

    Resources

    References

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