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Official Full Name chromobox homolog 4
Synonyms CBX4; chromobox homolog 4; chromobox homolog 4 (Drosophila Pc class); E3 SUMO-protein ligase CBX4; hPC2; NBP16; NS5ATP1 binding protein 16; Pc class 2 homolog (Drosophila); PC2; Pc class 2 homolog; polycomb 2 homolog; NS5ATP1-binding protein 16; chromobox
    • Species :
    • Chicken
    • Human
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CBX4-0482H Recombinant Human CBX4 Protein, GST-Tagged Wheat Germ GST
    Human CBX4-10769H Recombinant Human CBX4, GST-tagged E.coli GST
    Human CBX4-7803HCL Recombinant Human CBX4 293 Cell Lysate HEK293 N/A
    Chicken CBX4-6210C Recombinant Chicken CBX4 Mammalian Cell His
    Zebrafish CBX4-11764Z Recombinant Zebrafish CBX4 Mammalian Cell His

    cbx4 involved in several pathways and played different roles in them. We selected most pathways cbx4 participated on our site, such as C-MYB transcription factor network, Cellular Senescence, Cellular responses to stress, which may be useful for your reference. Also, other proteins which involved in the same pathway with cbx4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    C-MYB transcription factor network CLTA; MYB; PIAS3; GATA1; TRIM28; CDK6; COL1A2; CEBPB; SLC25A3; PTCRA
    Cellular Senescence EED; CBX6; CDKN2B; MINK1; SUZ12B; H1F0; CBX8B; TERF2IP; TXN; RBBP7
    Cellular responses to stress TXN; EGLN3; MINK1; HIF3A; HBXIP; DYNLL2A; C11orf73; HIST4H4; RPS19BP1; ULK1A
    Metabolism of proteins DAD1; MTX2; CNIH3; KCNA3; STT3A; PFDN6; IGFBP2; GALNTL5; PDIA6; PROZ
    Oxidative Stress Induced Senescence MINK1; SUZ12A; SUZ12; PHC1; CBX4; RING1; KDM6B; CBX8A; CBX8B; RNF2
    Post-translational protein modification DPH3; EIF5A; MPDU1A; TRAPPC9; TRAPPC6A; GALNTL2; CBX4; NANP; NSMCE1; ST6GALNAC2
    Regulation of retinoblastoma protein GSC; BRD2; ATF7; AATF; CBX4; BGLAP; SMARCB1; ELF1; MYOD1; CKM
    SUMO E3 ligases SUMOylate target proteins PHC1; NSMCE4A; SMC5; NSMCE2; CBX8; RNF2; SCMH1; CBX4; EID3; NSMCE1

    cbx4 has several biochemical functions, for example, SUMO binding, SUMO transferase activity, chromatin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by cbx4 itself. We selected most functions cbx4 had, and list some proteins which have the same functions with cbx4. You can find most of the proteins on our site.

    Function Related Protein
    SUMO binding RPS3; HERC2; TDG; USPL1; PML; USP25; CBX4; TOLLIP
    SUMO transferase activity SUMO4; SUMO3; PIAS3; UBE2IB; NSMCE2; CBX4; MUL1; UBE2IA; UBE2I; SUMO1
    chromatin binding HCFC1; SMAD6; APITD1; TADA2A; PATZ1; POU1F1; CSNK2B; HESX1; ATRX; TAL1
    enzyme binding TGFB1; PUS7; FOXO4; TAF10; PDE4DIP; BIRC5; HDAC10; MST1R; GSTM2; SPDL1
    ligase activity PJA2; TRIM58; RAD18; PET112L; RNF187; TRIM13; COP1; ITCH; RNF40; SIAH1
    methylated histone binding ING2; ING4; CDYL2; LRWD1; CBX7; PHF1; PHF8; L3MBTL1; GLYR1; ING1
    phosphoprotein binding RRAGA; MID2; PITX2; CSNK1D; CBX4; APTX; SERPINB1A; CACNB2; PRKCSH; IGF2R
    protein binding KTN1; CLTB; YWHAG; ELOVL6; ACOT8; SRGAP2; XAB2; USP14; ASPA; RAD51
    single-stranded RNA binding IFIT5; POLR2GL; TLR7; CBX8; HNRNPF; ANXA1; PIWIL1; ZFP36; DLX2; JMJD6
    transcription corepressor activity DRAP1; TFCP2L1; HDAC7; AES; HOMEZA; CRYM; MECP2; MYBBP1A; NR2F2; PPP1R13L
    transcription regulatory region DNA binding PAX2; CREB3L2; SOX2; PROX1; SFPQ; TRP63; NKX2; CTNNB1; ZFP513; KLF15

    cbx4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with cbx4 here. Most of them are supplied by our site. Hope this information will be useful for your research of cbx4.

    BMI1; HIF1A

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