CCT8
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Official Full Name
chaperonin containing TCP1, subunit 8 (theta) -
Overview
T-complex protein 1 subunit theta is a protein that in humans is encoded by the CCT8 gene. -
Synonyms
CCT8;chaperonin containing TCP1, subunit 8 (theta);C21orf112, chromosome 21 open reading frame 112;T-complex protein 1 subunit theta;Cctq;PRED71;C21orf112;CCT 8;CCT theta;Chaperonin containing TCP1 subunit 8 (theta);Chaperonin subunit 8 (Theta) (Predicted), isoform CRA_a;Chaperonin subunit 8 (theta);Chromosome 21 open reading frame 112;D21S246;KIAA0002;Renal carcinoma antigen NY REN 15;T complex protein 1 subunit theta;T complex protein 1 theta subunit;TCP 1 theta;Tcpq;CCT-theta;TCP-1-theta;renal carcinoma antigen NY-REN-15;T-complex protein 1, theta subunit
Recombinant Proteins
- Human
- Zebrafish
- Chicken
- Mouse
- Cynomolgus
- Rhesus macaque
- E.coli
- Wheat Germ
- Mammalian Cells
- HEK293
- In Vitro Cell Free System
- GST
- His
- Non
- Avi
- Fc
- DDK
- Myc
Involved Pathway
CCT8 involved in several pathways and played different roles in them. We selected most pathways CCT8 participated on our site, such as Assembly of the primary cilium,Association of TriC/CCT with target proteins during biosynthesis,BBSome-mediated cargo-targeting to cilium, which may be useful for your reference. Also, other proteins which involved in the same pathway with CCT8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Chaperonin-mediated protein folding | PFDN1,PFDN2,CCT2,CCT4,TCP1,TUBB4B,PFDN5,FBXW4,CCT3,FBXW2 |
| BBSome-mediated cargo-targeting to cilium | BBS5,LZTFL1,SETD6,TTC8,BBS9,BBS12,SSTR3,TCP1,BBS1,PROL1 |
| Association of TriC/CCT with target proteins during biosynthesis | KIFC3,FKBP9,FBXL5,NOP56,CCT4,CCT5,TCP1,FBXW4,FBXW5,FBXW9 |
| Formation of tubulin folding intermediates by CCT/TriC | TUBB4B,CCT7,TCP1,CCT5,CCT4,CCT6A,TUBB4A,TUBA3D,TUBA1B,CCT2 |
| Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding | CCT4,PFDN1,CCT3,TUBA3D,PFDN6,CCT5,CCT2,VBP1,PFDN4,PFDN2 |
| Cargo trafficking to the periciliary membrane | ARF4A,CCT3,CNGA5,BBS7,BBS12,NPHP3,CNGA2,EXOC8,EXOC3,MKKS |
| Assembly of the primary cilium | IFT27,MAPRE1,BBS7,WDR34,TCTEX1D2,TTC30A2,DYNLL2,NINL,ACTR1A,IFT43 |
| Folding of actin by CCT/TriC | CCT3,CCT7,CCT6A,TCP1,CCT5,CCT2,CCT4 |
Protein Function
CCT8 has several biochemical functions, for example, ATP binding,ATPase activity, coupled,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CCT8 itself. We selected most functions CCT8 had, and list some proteins which have the same functions with CCT8. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATP binding | MAP3K6,UBE2KB,NLRP4B,DHX36,ABL1,HYOU1,DDX51,RPS6KA5,EIF2AK2,CCT3 |
| unfolded protein binding | HSPE1,MKKS,SCG5,CLGN,HSPA6,TBCA,HSPA5,PFDN6,CCT5,HSP26 |
| protein binding | TCF7L2,CARD8,CORO1B,TH,TNNI3,COBRA1,FAM54A,LDLRAD1,TRPM8,SAFB |
| ATPase activity, coupled | HSPA8,PEX1,VPS4B,HSPA1A,MYO1E,HSPA6,MYH3,ABCB1A,VPS4A,NSF |
Interacting Protein
CCT8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CCT8 here. Most of them are supplied by our site. Hope this information will be useful for your research of CCT8.
PPP4C;PPP2CB;PPP2CA;STRN3;ILK;STRN;JAK3;IGBP1
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