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Official Full Name CDC42 effector protein (Rho GTPase binding) 4
Background The product of this gene is a member of the CDC42-binding protein family. Members of this family interact with Rho family GTPases and regulate the organization of the actin cytoskeleton. This protein has been shown to bind both CDC42 and TC10 GTPases in a GTP-dependent manner. When overexpressed in fibroblasts, this protein was able to induce pseudopodia formation, which suggested a role in inducing actin filament assembly and cell shape control.
Synonyms CDC42EP4; CDC42 effector protein (Rho GTPase binding) 4; cdc42 effector protein 4; binder of Rho GTPases 4; BORG4; CEP4; KAIA1777; MGC3740; MGC17125; BORG4_HUMAN
    • Species :
    • Human
    • Mouse
    • Rhesus Macaque
    • Source :
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • Myc/DDK
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CDC42EP4-0949H Recombinant Human CDC42EP4 Protein, GST-Tagged Wheat Germ GST
    Human CDC42EP4-2299H Recombinant Human CDC42EP4 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human CDC42EP4-3122H Recombinant Human CDC42EP4 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human CDC42EP4-323HCL Recombinant Human CDC42EP4 cell lysate N/A
    Mouse Cdc42ep4-2077M Recombinant Mouse Cdc42ep4 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Rhesus Macaque CDC42EP4-766R Recombinant Rhesus monkey CDC42EP4 Protein, His-tagged Mammalian Cell His

    cdc42ep4 involved in several pathways and played different roles in them. We selected most pathways cdc42ep4 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with cdc42ep4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    cdc42ep4 has several biochemical functions, for example, GTP-Rho binding, GTPase activator activity, poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by cdc42ep4 itself. We selected most functions cdc42ep4 had, and list some proteins which have the same functions with cdc42ep4. You can find most of the proteins on our site.

    Function Related Protein
    GTPase activator activity ARHGAP10; RABEP2; GDI1; ARHGAP32; ARHGAP42; TBC1D2; ASAP1A; DOCK2; ARHGAP36; TBC1D25
    poly(A) RNA binding HNRNPA0; NPM3; FAM120B; DDX46; TMSB4X; SUPT6H; PDIA4; PRKDC; IMMT; SPATS2
    protein binding ZNF205; KPNA6; ETL4; LCE3E; SERPINA1; UGGT2; E2F5; MLST8; LCP2; RNF213

    cdc42ep4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with cdc42ep4 here. Most of them are supplied by our site. Hope this information will be useful for your research of cdc42ep4.

    FAM9B; SRPK2; SRPK1; PA; CDC42; WDR6; Sept7; Sept2; Sept9; Kctd5

    Abolghait, SK; Iida, T; et al. Recombinant AexU effector protein of Aeromonas veronii bv. sobria disrupts the actin cytoskeleton by downregulation of Rac1 and induces direct cytotoxicity to beta 4-integrin expressing cell lines. MICROBIAL PATHOGENESIS 51:454-465(2011).
    Wang, YQ; Ohkubo, T; et al. Enhanced cell-substratum adhesion of E-cadherin-expressing cells is mediated by activation of the small GTPase protein, Rac1. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE 17:637-642(2006).

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