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CDK10

Official Full Name

cyclin-dependent kinase 10
Overview

The protein encoded by this gene belongs to the CDK subfamily of the Ser/Thr protein kinase family. The CDK subfamily members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and are known to be essential for cell cycle progression. This kinase has been shown to play a role in cellular proliferation and its function is limited to cell cycle G2-M phase. Multiple transcript variants encoding different isoforms have been found for this gene.
Synonyms

CDK10; cyclin-dependent kinase 10; cyclin dependent kinase (CDC2 like) 10; PISSLRE; CDC2-related protein kinase; cell division protein kinase 10; cyclin-dependent kinase (CDC2-like) 10; cyclin-dependent kinase related protein; serine/threonine protein kin;

Type

Recombinant Proteins
Cell & Tissue Lysates

Species

Chicken
Human
Mouse
Zebrafish

Source

E.coli
HEK293
HEK293T
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

GST
His
Myc
DDK
Myc|DDK
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	CDK10-0999H	Recombinant Human CDK10 Protein, GST-Tagged	Wheat Germ	GST		Inquiry
Human	CDK10-11045H	Recombinant Human CDK10, His-tagged	E.coli	His	1-283a.a.	$319 / 25ug
Human	CDK10-326HCL	Recombinant Human CDK10 cell lysate		N/A		Inquiry
Human	CDK10-3177HF	Recombinant Full Length Human CDK10 Protein, GST-tagged	In Vitro Cell Free System	GST	331 amino acids	Inquiry
Human	CDK10-3144H	Recombinant Human CDK10 Protein, MYC/DDK-tagged	HEK293	Myc/DDK		Inquiry
Human	CDK10-645H	Recombinant Human CDK10 Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc/DDK		Inquiry
Mouse	Cdk10-2084M	Recombinant Mouse Cdk10 Protein, Myc/DDK-tagged	HEK293T	Myc/DDK		Inquiry
Zebrafish	CDK10-2393Z	Recombinant Zebrafish CDK10	Mammalian Cell	His		Inquiry
Chicken	CDK10-3765C	Recombinant Chicken CDK10	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
CDK10 Related Articles

CDK10 involved in several pathways and played different roles in them. We selected most pathways CDK10 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CDK10 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

CDK10 has several biochemical functions, for example, ATP binding, cyclin-dependent protein serine/threonine kinase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CDK10 itself. We selected most functions CDK10 had, and list some proteins which have the same functions with CDK10. You can find most of the proteins on our site.

Function	Related Protein
ATP binding	NETO2;ILK;PAN3;GRK1B;PRPF4BA;CKMB;CHORDC1;QARS;PFKL
cyclin-dependent protein serine/threonine kinase activity	CDK19;NAT1;CDKL2;CDK5;CDK11A;MOK;CDK10;CDK18;CDK6
protein binding	H2-KE2;CBR2;ZBTB1;XRCC5;UBL4B;HSPA14;BST2;SMCO3;CHRM3

CDK10 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CDK10 here. Most of them are supplied by our site. Hope this information will be useful for your research of CDK10.

PIN1; HSP90AB1; ETS2; SEMG2; Pin1; raf1_human_gene; Wdr48; PRKD2

Ehrenschwender, M; Bittner, S; et al. XIAP-targeting drugs re-sensitize PIK3CA-mutated colorectal cancer cells for death receptor-induced apoptosis. CELL DEATH & DISEASE 5:-(2014).

Zhu, BT; Xiahou, ZK; et al. MTHFR promotes heterochromatin maintenance. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 447:702-706(2014).