CEP152

  • Official Full Name

    centrosomal protein 152kDa
  • Overview

    This gene encodes a protein that is thought to be involved with centrosome function. Mutations in this gene have been associated with primary microcephaly (MCPH4). Alternative splicing results in multiple transcript variants.
  • Synonyms

    CEP152;centrosomal protein 152kDa;MCPH4, microcephaly, primary autosomal recessive 4;centrosomal protein of 152 kDa;asterless;KIAA0912;SCKL5;MCPH4;FLJ21594
Cat.# Product name Source (Host) Species Tag Protein Length Price
CEP152-3300M Recombinant Mouse CEP152 Protein Mammalian Cells Mouse His
CEP152-1588M Recombinant Mouse CEP152 Protein, His (Fc)-Avi-tagged HEK293 Mouse Avi&Fc&His
CEP152-1588M-B Recombinant Mouse CEP152 Protein Pre-coupled Magnetic Beads HEK293 Mouse

    Involved Pathway

    CEP152 involved in several pathways and played different roles in them. We selected most pathways CEP152 participated on our site, such as Anchoring of the basal body to the plasma membrane,Assembly of the primary cilium,Cell Cycle, which may be useful for your reference. Also, other proteins which involved in the same pathway with CEP152 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Anchoring of the basal body to the plasma membrane TUBB4A,TCTN1,SDCCAG8,ODF2,CEP97,NEK2,B9D2,MAPRE1B,CLASP1,CDK5RAP2
    Cell Cycle, Mitotic PHF8,CTDNEP1,CEP76,NIPBLA,AHCTF1,NINL,CLASP1A,SETB,BLZF1,SPDL1
    G2/M Transition NUMA1,MAPRE1A,ACTR1A,CDK11A,CDK11B,TUBGCP3,CEP76,FOXM1,BORA,PLK4
    Loss of Nlp from mitotic centrosomes MAPRE1B,CEP78,CEP290,SDCCAG8,ODF2,TUBG1,SSNA1,CEP63,MAPRE1,DCTN1A
    Assembly of the primary cilium TUBG1,BBS1,MAPRE1A,DCTN1A,CEP63,TMEM67,IFT81,TTC30B,ODF2,CEP78
    Cell cycle MCM9,RBL2,POT1A,MCM6L,TERF2IP,CENPL,DULLARD,CDK2,ANAPC2,LEMD3
    Centrosome maturation NDE1,CENPJ,CEP63,CEP78,DYNC1I2,CEP164,TUBG1,CEP57,CKAP5,ODF2B
    Loss of proteins required for interphase microtubule organizationfrom the centrosome CEP72,ODF2,MAPRE1B,CP110,DCTN1A,MAPRE1,TUBG1,CEP135,CEP63,SSNA1

    Protein Function

    CEP152 has several biochemical functions, for example, protein binding,protein kinase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CEP152 itself. We selected most functions CEP152 had, and list some proteins which have the same functions with CEP152. You can find most of the proteins on our site.

    Function Related Protein
    protein binding ARR3,IRF8,IGSF21B,MAP3K7,PTPRN,TSPO,NLRP3,RAB26,ARHGEF4,DIAP1
    protein kinase binding RPS6,GSK3B,BCL2L1,CCNK,USF1,MAP2K3,JAK2,CDK5RAP3,GRB7,SOCS1

    Interacting Protein

    CEP152 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CEP152 here. Most of them are supplied by our site. Hope this information will be useful for your research of CEP152.

    DYNLL1;CEP63;SPAG5;KNSTRN;CEP152;CENPF;HNRNPD;q53ez1_human;DKFZp686P17171;DYNLL2;SH3PXD2B;b4dnw0_human;AMACR;PCM1;DST;KIAA1211

    Resources

    References

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