CEP152
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Official Full Name
centrosomal protein 152kDa -
Overview
This gene encodes a protein that is thought to be involved with centrosome function. Mutations in this gene have been associated with primary microcephaly (MCPH4). Alternative splicing results in multiple transcript variants. -
Synonyms
CEP152;centrosomal protein 152kDa;MCPH4, microcephaly, primary autosomal recessive 4;centrosomal protein of 152 kDa;asterless;KIAA0912;SCKL5;MCPH4;FLJ21594
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| CEP152-3300M | Recombinant Mouse CEP152 Protein | Mammalian Cells | Mouse | His |
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| CEP152-1588M | Recombinant Mouse CEP152 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | Avi&Fc&His |
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| CEP152-1588M-B | Recombinant Mouse CEP152 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
CEP152 involved in several pathways and played different roles in them. We selected most pathways CEP152 participated on our site, such as Anchoring of the basal body to the plasma membrane,Assembly of the primary cilium,Cell Cycle, which may be useful for your reference. Also, other proteins which involved in the same pathway with CEP152 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| G2/M Transition | MYBL2,TCTN2,DCTN1,CP110,CEP57,CLASP1A,ACTR1A,CDK11A,DCTN2,PCM1 |
| Loss of proteins required for interphase microtubule organizationfrom the centrosome | MAPRE1,NDE1,DCTN1A,CEP290,CEP76,SDCCAG8,MAPRE1A,CEP78,TSGA14,CEP72 |
| Cell cycle | CCP110,SMC1AL,CEP135,WEE1,ANAPC2,CCND2,CHEK1,TFDP2,NEK2,GMNN |
| Cell Cycle, Mitotic | CDK4,ZW10,MYCA,SET,PDS5B,KIF18A,RCC2,FGFR1OP,KIF2C,VRK1 |
| Anchoring of the basal body to the plasma membrane | CSNK1E,TMEM216,CCDC123,DYNC1I2,NPHP1,MAPRE1A,CEP89,DCTN1,CEP78,BBS13 |
| Assembly of the primary cilium | MARK4,CCDC41,CCT8,DCTN2,TSGA14,TCTN3,PKD2,BBS2,IFT74,DYNLL2A |
| Loss of Nlp from mitotic centrosomes | DCTN1A,NDE1,CP110,CEP63,OFD1,TSGA14,PLK4,CENPJ,SSNA1,SDCCAG8 |
| Centrosome maturation | SDCCAG8,CP110,TUBG1,TUBB4B,CEP72,TUBG2,CEP70,TUBGCP5,OFD1,NEDD1 |
Protein Function
CEP152 has several biochemical functions, for example, protein binding,protein kinase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CEP152 itself. We selected most functions CEP152 had, and list some proteins which have the same functions with CEP152. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein kinase binding | VDAC1,NCS1,SPDYB,NEFH,SHC1,PTPN2,DUSP3,PDPK1,RPS3,ILK |
| protein binding | ARL6IP4,CPSF6,DNM1,SH2D2A,CYC1,ZCCHC12,GRB10,XIRP2,CCDC28B,GP5 |
Interacting Protein
CEP152 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CEP152 here. Most of them are supplied by our site. Hope this information will be useful for your research of CEP152.
DYNLL1;CEP63;SPAG5;KNSTRN;CEP152;CENPF;HNRNPD;q53ez1_human;DKFZp686P17171;DYNLL2;SH3PXD2B;b4dnw0_human;AMACR;PCM1;DST;KIAA1211
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