cep63

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cep63

Official Full Name CEP63 centrosomal protein 63kDa [ Homo sapiens ]
Background This gene encodes a protein with six coiled-coil domains. The protein is localized to the centrosome, a non-membraneous organelle that functions as the major microtubule-organizing center in animal cells. Several alternatively spliced transcript variants have been found, but their biological validity has not been determined.
Synonyms centrosomal protein 63kDa; FLJ13386; centrosomal protein of 63 kDa; centrosome protein CEP63; Cep63
    • Species :
    • Chicken
    • Human
    • Rat
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CEP63-11114H Recombinant Human CEP63, GST-tagged E.coli GST
    Human CEP63-1138H Recombinant Human CEP63 Protein, GST-Tagged Wheat Germ GST
    Human CEP63-3210H Recombinant Human CEP63 Protein, His-tagged E.coli His
    Human CEP63-7571HCL Recombinant Human CEP63 293 Cell Lysate HEK293 N/A
    Rat CEP63-1345R Recombinant Rat CEP63 Protein Mammalian Cell His
    Chicken CEP63-4039C Recombinant Chicken CEP63 Mammalian Cell His
    Zebrafish CEP63-10880Z Recombinant Zebrafish CEP63 Mammalian Cell His

    cep63 involved in several pathways and played different roles in them. We selected most pathways cep63 participated on our site, such as Anchoring of the basal body to the plasma membrane, Assembly of the primary cilium, Cell Cycle, which may be useful for your reference. Also, other proteins which involved in the same pathway with cep63 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Anchoring of the basal body to the plasma membrane CCP110; DCTN1A; DCTN1; NEK2; CEP78; RAB3IP; NPHP4; HAUS2; FBF1; CEP72
    Assembly of the primary cilium TMEM216; IFT-20; FLR; CEP290; DYNLL2B; OFD1; MAPRE1; TTBK2; EXOC3; CCDC123
    Cell Cycle TP53BP1; SPDL1; OIP5; FKBP6; PDS5B; CDC14AA; NDEL1B; CENPA; HIST4H4; MCPH1
    Cell Cycle, Mitotic APITD1; TUBB4B; HAUS2; PCM1; CENPH; NSL1; STAG2; DYNC1H1; PDS5B; WAPAL
    Centrosome maturation SDCCAG8; MAPRE1B; PCM1; CEP290; TUBGCP5; CDK11B; CSNK1D; HAUS2; OFD1; CSNK1E
    G2/M Transition MYBL2; CEP63; SSNA1; CEP135; HAUS2; ODF2B; DCTN2; CDK11A; TSGA14; CKAP5
    Loss of Nlp from mitotic centrosomes SSNA1; PCM1; ODF2B; CENPJ; HAUS2; CEP164; PLK4; CEP152; MAPRE1B; CEP135
    Loss of proteins required for interphase microtubule organizationfrom the centrosome CEP57; CEP164; TUBG1; CEP70; CP110; NEDD1; TSGA14; CEP63; CEP290; CENPJ

    cep63 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by cep63 itself. We selected most functions cep63 had, and list some proteins which have the same functions with cep63. You can find most of the proteins on our site.

    Function Related Protein
    protein binding SERPINE2; PIM1; CNOT1; FBXW8; FRMD8; MYLK; RARG; MTERF; NPPA; Ctsl

    cep63 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with cep63 here. Most of them are supplied by our site. Hope this information will be useful for your research of cep63.

    DTNB; TBC1D15; SMARCE1; DISC1; TSHZ3

    Alsara, M; Loffler, H; et al. Cep63 Recruits Cdk1 to the Centrosome-Letter. CANCER RESEARCH 75:777-778(2015).
    Ma, LN; Quigley, I; et al. Multicilin drives centriole biogenesis via E2f proteins. GENES & DEVELOPMENT 28:1461-1471(2014).

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