|Official Full Name||calcium and integrin binding 1 (calmyrin)|
|Background||This gene encodes a member of the EF-hand domain-containing calcium-binding superfamily. The encoded protein interacts with many other proteins, including the platelet integrin alpha-IIb-beta-3, DNA-dependent protein kinase, presenilin-2, focal adhesion kinase, p21 activated kinase, and protein kinase D. The encoded protein may be involved in cell survival and proliferation, and is associated with several disease states including cancer and Alzheimers disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2013]|
|Synonyms||CIB1; calcium and integrin binding 1 (calmyrin); CIB; CIBP; KIP1; PRKDCIP; SIP2-28; calcium and integrin-binding protein 1; DNA-PK interaction protein; DNA-PKcs-interacting protein; SNK-interacting protein 2-28; DNA-dependent protein kinase interacting protein;|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
CIB1 involved in several pathways and played different roles in them. We selected most pathways CIB1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CIB1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
CIB1 has several biochemical functions, for example, Ras GTPase binding, calcium ion binding, calcium-dependent protein kinase inhibitor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CIB1 itself. We selected most functions CIB1 had, and list some proteins which have the same functions with CIB1. You can find most of the proteins on our site.
|Ras GTPase binding||RAP1GAP; SPHK2; MAPKAP1; MAP2K1; RGL3; SH3BP4; RIN1; PLCE1; RAP1A; CIB1|
|calcium ion binding||SLIT1; KCNIP1B; PADI3; RASGRP4; SYT7B; CAPN2B; PRSS3; DSG1; MYLPF; ENPP1|
|calcium-dependent protein kinase inhibitor activity||CAMK2N1; CAMK2N2; CIB1|
|ion channel binding||NOS1; KCNE4; LYN; KCNJ11; RIMS1; TRAPPC2; ID2; SRC; ACTN4; SLC14A2|
|protein anchor||SUN1; CIB1; RAPSN; ALG14; NUP153; AKAP6; SUN5; PDCD6; SLC4A1; MYH9|
|protein binding||RPIA; PIK3CD; APOD; ZMAT2; TRPC4AP; NAT9; STARD10; LMO2; SEC22C; RNF149|
|protein serine/threonine kinase inhibitor activity||CIB1; H2AFY; SPRED2; SPRED1; SPRY2|
CIB1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CIB1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CIB1.
WASL; PSEN2; ITGA2; PAK1; CDK4; EXOSC10; parC; aas; ompA4; thrS1; resE; ydeE