CIDEA

Official Full Name

cell death-inducing DFFA-like effector a
Overview

This gene encodes the homolog of the mouse protein Cidea that has been shown to activate apoptosis. This activation of apoptosis is inhibited by the DNA fragmentation factor DFF45 but not by caspase inhibitors. Mice that lack functional Cidea have higher metabolic rates, higher lipolysis in brown adipose tissue and higher core body temperatures when subjected to cold. These mice are also resistant to diet-induced obesity and diabetes. This suggests that in mice this gene product plays a role in thermogenesis and lipolysis. Alternatively spliced transcripts have been identified.
Synonyms

CIDEA; cell death-inducing DFFA-like effector a; cell death activator CIDE-A; CIDE A; CIDE-A;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
Mouse

Source

E.coli
HEK293
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	CIDEA-1361H	Recombinant Human CIDEA Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	CIDEA-358HCL	Recombinant Human CIDEA cell lysate		Non		Inquiry
Human	CIDEA-1834H	Recombinant Full Length Human CIDEA protein, His & GST-tagged	E.coli	His&GST	Met1~Gly219	Inquiry
Human	CIDEA-1848HF	Recombinant Full Length Human CIDEA Protein, GST-tagged	In Vitro Cell Free System	GST	253 amino acids	Inquiry
Mouse	CIDEA-3471M	Recombinant Mouse CIDEA Protein	Mammalian Cell	His		Inquiry
Mouse	CIDEA-1690M	Recombinant Mouse CIDEA Protein, His (Fc)-Avi-tagged	HEK293	His&Fc&Avi		Inquiry
Mouse	Cidea-789M	Recombinant Mouse Cidea Protein, His-tagged	E.coli	His	Met1-Met217	Inquiry
Mouse	CIDEA-1690M-B	Recombinant Mouse CIDEA Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Chicken	CIDEA-4130C	Recombinant Chicken CIDEA	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
Other Resource

CIDEA involved in several pathways and played different roles in them. We selected most pathways CIDEA participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CIDEA were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

CIDEA has several biochemical functions, for example, protein homodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CIDEA itself. We selected most functions CIDEA had, and list some proteins which have the same functions with CIDEA. You can find most of the proteins on our site.

Function	Related Protein
protein homodimerization activity	KCNE2;ASCL1;RAB11FIP4;SNX2;NLRC4;TCF4;GRM6;ZHX3;USH2A

CIDEA has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CIDEA here. Most of them are supplied by our site. Hope this information will be useful for your research of CIDEA.

Dlg4; NR1H2; ZBTB16