CLEC6A

  • Official Full Name

    C-type lectin domain family 6, member A

  • Overview

    Like dectin-1 (CLEC7A; MIM 606264), CLEC6A, or dectin-2, is a type II membrane receptor with an extracellular C-type lectin-like domain fold. However, unlike dectin-1, dectin-2 lacks an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain (Kanazawa et al., 2004
  • Synonyms

    CLEC6A; C-type lectin domain family 6, member A; C type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 10 , CLECSF10; C-type lectin domain family 6 member A; dectin 2; C type lectin domain family 6 member A; C type lectin superfamily member 10; C-type lectin superfamily member 10; CLC6A_HUMAN; CLEC4N; CLECSF10; DC associated C type lectin 2; DC-associated C-type lectin 2; Dectin-2; Dectin2; Dendritic cell associated lectin 2; Dendritic cell-associated C-type lectin 2; OTTHUMP00000239172; C-type (calcium dependent, carbohydrate-recognition domain) lectin, sup;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Rattus norvegicus (Rat)
  • Rhesus Macaque
  • E.coli expression system
  • HEK293
  • Human Cell
  • Mammalian Cell
  • Mouse myeloma cell line
  • Fc
  • His
  • Avi
  • Non
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CLEC6A-8528H Recombinant Human CLEC6A protein, hFc-tagged HEK293 Fc Thr42-Leu209
Human CLEC6A-1290HCL Recombinant Human CLEC6A cell lysate Human Cell Non
Human CLEC6A-8529H Recombinant Human CLEC6A protein, His-tagged HEK293 His Thr42-Leu209
Human CLEC6A-13H Recombinant Human CLEC6A Protein, Thr46-Leu209, N-6×His tagged Mouse myeloma cell line His Thr46-Leu209
Rattus norvegicus (Rat) RFL28685RF Recombinant Full Length Rat C-Type Lectin Domain Family 6 Member A(Clec6A) Protein, His-Tagged E.coli expression system His Full Length (1-209)
Rhesus Macaque CLEC6A-906R Recombinant Rhesus monkey CLEC6A Protein, His-tagged Mammalian Cell His
Rhesus Macaque CLEC6A-731R-B Recombinant Rhesus Macaque CLEC6A Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque CLEC6A-731R Recombinant Rhesus Macaque CLEC6A Protein, His (Fc)-Avi-tagged HEK293 His&Fc&Avi
  • Involved Pathway
  • Protein Function
  • Interacting Protein

CLEC6A involved in several pathways and played different roles in them. We selected most pathways CLEC6A participated on our site, such as C-type lectin receptors (CLRs), Dectin-2 family, Immune System, which may be useful for your reference. Also, other proteins which involved in the same pathway with CLEC6A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
C-type lectin receptors (CLRs)CLEC4D;UBE2V1;IL1B2;MALT1;CLEC6A;CASP8L1;ITPR2;AHCYL1;TAB1
Dectin-2 familyCLEC4D;CLEC4A;CLEC6A
Immune SystemEGR1;ERAP2;LAT2;MYO1C;TREML2;IFIT8;GAN;HCST;CSHL1
Innate Immune SystemPOLR3GLA;DEFA3;DEFB121;BTR12;MYO1C;BTR09;CLEC4D;SIGLEC15;DEFA6

CLEC6A has several biochemical functions, for example, carbohydrate binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CLEC6A itself. We selected most functions CLEC6A had, and list some proteins which have the same functions with CLEC6A. You can find most of the proteins on our site.

Function Related Protein
carbohydrate bindingZP3;CD248;KLRB1F;KLRK1;Reg2;ASGR1;GANAB;NPTX2;LGALS3

CLEC6A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CLEC6A here. Most of them are supplied by our site. Hope this information will be useful for your research of CLEC6A.

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