CLEC6A

Official Full Name

C-type lectin domain family 6, member A
Overview

Like dectin-1 (CLEC7A; MIM 606264), CLEC6A, or dectin-2, is a type II membrane receptor with an extracellular C-type lectin-like domain fold. However, unlike dectin-1, dectin-2 lacks an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain (Kanazawa et al., 2004
Synonyms

CLEC6A; C-type lectin domain family 6, member A; C type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 10 , CLECSF10; C-type lectin domain family 6 member A; dectin 2; C type lectin domain family 6 member A; C type lectin superfamily member 10; C-type lectin superfamily member 10; CLC6A_HUMAN; CLEC4N; CLECSF10; DC associated C type lectin 2; DC-associated C-type lectin 2; Dectin-2; Dectin2; Dendritic cell associated lectin 2; Dendritic cell-associated C-type lectin 2; OTTHUMP00000239172; C-type (calcium dependent, carbohydrate-recognition domain) lectin, sup;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Rattus norvegicus (Rat)
Rhesus Macaque

Source

E.coli expression system
HEK293
Human Cell
Mammalian Cell
Mouse myeloma cell line

Tag

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	CLEC6A-8528H	Recombinant Human CLEC6A protein, hFc-tagged	HEK293	Fc	Thr42-Leu209	Inquiry
Human	CLEC6A-1290HCL	Recombinant Human CLEC6A cell lysate	Human Cell	Non		Inquiry
Human	CLEC6A-8529H	Recombinant Human CLEC6A protein, His-tagged	HEK293	His	Thr42-Leu209	Inquiry
Human	CLEC6A-13H	Recombinant Human CLEC6A Protein, Thr46-Leu209, N-6×His tagged	Mouse myeloma cell line	His	Thr46-Leu209	Inquiry
Rattus norvegicus (Rat)	RFL28685RF	Recombinant Full Length Rat C-Type Lectin Domain Family 6 Member A(Clec6A) Protein, His-Tagged	E.coli expression system	His	Full Length (1-209)	Inquiry
Rhesus Macaque	CLEC6A-906R	Recombinant Rhesus monkey CLEC6A Protein, His-tagged	Mammalian Cell	His		Inquiry
Rhesus Macaque	CLEC6A-731R-B	Recombinant Rhesus Macaque CLEC6A Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rhesus Macaque	CLEC6A-731R	Recombinant Rhesus Macaque CLEC6A Protein, His (Fc)-Avi-tagged	HEK293	His&Fc&Avi		Inquiry

Involved Pathway
Protein Function
Interacting Protein

CLEC6A involved in several pathways and played different roles in them. We selected most pathways CLEC6A participated on our site, such as C-type lectin receptors (CLRs), Dectin-2 family, Immune System, which may be useful for your reference. Also, other proteins which involved in the same pathway with CLEC6A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
C-type lectin receptors (CLRs)	CLEC4D;UBE2V1;IL1B2;MALT1;CLEC6A;CASP8L1;ITPR2;AHCYL1;TAB1
Dectin-2 family	CLEC4D;CLEC4A;CLEC6A
Immune System	EGR1;ERAP2;LAT2;MYO1C;TREML2;IFIT8;GAN;HCST;CSHL1
Innate Immune System	POLR3GLA;DEFA3;DEFB121;BTR12;MYO1C;BTR09;CLEC4D;SIGLEC15;DEFA6

CLEC6A has several biochemical functions, for example, carbohydrate binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CLEC6A itself. We selected most functions CLEC6A had, and list some proteins which have the same functions with CLEC6A. You can find most of the proteins on our site.

Function	Related Protein
carbohydrate binding	ZP3;CD248;KLRB1F;KLRK1;Reg2;ASGR1;GANAB;NPTX2;LGALS3

CLEC6A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CLEC6A here. Most of them are supplied by our site. Hope this information will be useful for your research of CLEC6A.