CNGA4

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CNGA4

Official Full Name cyclic nucleotide gated channel alpha 4
Background CNGA4 is a modulatory subunit of vertebrate cyclic nucleotide-gated membrane channels that transduce odorant signals (Munger et al., 2001
Synonyms CNGA4; cyclic nucleotide gated channel alpha 4; CNCA2, CNGB2, cyclic nucleotide gated channel beta 2; cyclic nucleotide-gated cation channel alpha-4; CNG5; OCNC2; OCNCb; Cgn2; CNCA2; CNG 4; CNG channel alpha 4; CNG4; Cnga4 cyclic nucleotide gated channel alpha 4; CNGB2; Cyclic nucleotide gated cation channel alpha 4; Cyclic nucleotide gated channel beta 2; Cyclic nucleotide gated olfactory channel subunit OCNC2; MGC126168; MGC126169; MGC130316; OCNCBETA; CNG channel alpha-4; CNG-4
    • Species :
    • Human
    • Mouse
    • Source :
    • in vitro E. coli
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • SUMO
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CNGA4-1558H Recombinant Human CNGA4 Protein, GST-tagged Wheat Germ GST
    Human CNGA4-2708H Recombinant Human CNGA4 Protein (1-575 aa), His-SUMO-tagged in vitro E. coli His/SUMO
    Mouse CNGA4-3647M Recombinant Mouse CNGA4 Protein Mammalian Cell His

    CNGA4 involved in several pathways and played different roles in them. We selected most pathways CNGA4 participated on our site, such as cAMP signaling pathway, Olfactory transduction, which may be useful for your reference. Also, other proteins which involved in the same pathway with CNGA4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    cAMP signaling pathway FSHB; RELA; RAF1; SOX9; MLLT4; GABBR2; RYR2; AKT2; GPR119; HCAR2
    Olfactory transduction OR1L6; OLFR498; OLFR688; OLFR1013; OR10C1; OR10A5; OR5B2; OLFR474; OR4D2; OLFR473

    CNGA4 has several biochemical functions, for example, cAMP binding, cGMP binding, intracellular cAMP activated cation channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CNGA4 itself. We selected most functions CNGA4 had, and list some proteins which have the same functions with CNGA4. You can find most of the proteins on our site.

    Function Related Protein
    cAMP binding PDE4D; RAPGEF4; RAPGEF3; PDE10A; PDE4A; PDE4B; CNGA2; CNMPD1; PDE11A; HCN2
    cGMP binding CNGA4; PDE6C; PRKG1A; PDE6H; PDE11A; CNGA3; PDE6G; CNGA2; PRKG1; PDE10A
    intracellular cAMP activated cation channel activity CNGA1; CNGA3; HCN2; CNGA4; CNGA5; HCN4
    intracellular cGMP activated cation channel activity CNGA5; CNGA1; AQP1; CNGA4; CNGA3; CNGA2
    intracellular cyclic nucleotide activated cation channel activity KCNA10; CNGA4
    ion channel activity KCNK3; GRIA3A; GRIN2A; SCN11A; GRIA3B; CNGA5; GRIA2A; TRPC7A; KCNH1A; CLCN1A
    nucleotide binding MAT2AA; SRPK1A; PRKACBA; EEF1A1A; VPRBP; AKAP17A; TUBA1L2; RAD51L3; GC3; HSP90AA1.1

    CNGA4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CNGA4 here. Most of them are supplied by our site. Hope this information will be useful for your research of CNGA4.

    Landry, Y; Gies, JP; et al. Drugs and their molecular targets: an updated overview. FUNDAMENTAL & CLINICAL PHARMACOLOGY 22:1-18(2008).
    Paillart, C; Zhang, K; et al. Cloning and molecular characterization of cGMP-gated ion channels from rod and cone photoreceptors of striped bass (M-saxatilis) retina. VISUAL NEUROSCIENCE 23:99-113(2006).

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