CNTN1

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CNTN1

Official Full Name contactin 1
Background The protein encoded by this gene is a member of the immunoglobulin superfamily. It is a glycosylphosphatidylinositol (GPI)-anchored neuronal membrane protein that functions as a cell adhesion molecule. It may play a role in the formation of axon connections in the developing nervous system. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Synonyms CNTN1; contactin 1; contactin-1; F3; glycoprotein gP135; GP135; neural cell surface protein F3
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Human Cell
    • Mammalian Cell
    • Sf21 Insect Cell
    • Tag :
    • Fc
    • Fc Chimera
    • His
    • GST
    • T7
    • Myc/DDK
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CNTN1-11411H Recombinant Human CNTN1, GST-tagged E.coli GST
    Human CNTN1-1597H Recombinant Human Contactin 1 Sf21 Insect Cell N/A
    Human CNTN1-166H Recombinant Human CNTN1, Fc-tagged HEK293 Fc
    Human CNTN1-3036HCL Recombinant Human CNTN1 cell lysate Human Cell N/A
    Human CNTN1-3288H Recombinant Human CNTN1 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human CNTN1-507H Recombinant Human CNTN1, Fc Chimera Sf21 Insect Cell Fc Chimera
    Human CNTN1-5803H Recombinant Human CNTN1 protein, His & T7-tagged E.coli His/T7
    Human CNTN1-6493H Recombinant Human CNTN1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human CNTN1-669H Recombinant Human CNTN1, Fc-His tagged Human Cell Fc/His
    Human CNTN1-670H Recombinant Human CNTN1, His tagged Human Cell His
    Mouse Cntn1-2228M Recombinant Mouse Cntn1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Mouse CNTN1-320M Recombinant Mouse Cntn1, His tagged Human Cell His
    Mouse CNTN1-996MCL Recombinant Mouse CNTN1 cell lysate Human Cell N/A
    Rat CNTN1-1503R Recombinant Rat CNTN1 Protein Mammalian Cell His
    Rhesus Macaque CNTN1-950R Recombinant Rhesus monkey CNTN1 Protein, His-tagged Mammalian Cell His
    Chicken CNTN1-1200C Recombinant Chicken CNTN1 Mammalian Cell His

    CNTN1 involved in several pathways and played different roles in them. We selected most pathways CNTN1 participated on our site, such as Activated NOTCH1 Transmits Signal to the Nucleus, Axon guidance, Cell adhesion molecules (CAMs), which may be useful for your reference. Also, other proteins which involved in the same pathway with CNTN1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Activated NOTCH1 Transmits Signal to the Nucleus JAG2; ADAM10; DNER; JAG1; DLK1; CNTN1; MIB1; DTX2
    Axon guidance SPNA1; FRS2B; RNF8; FGFR1B; KIF4A; ROBO3; RASGRP1; ARPC5; CLTB; CDC42
    Cell adhesion molecules (CAMs) NCAM1B; CLDNJ; Siglec1; MAG; CD28; Itgam&Itgb2; CLDN10; CLDN22; CLDNK; CD8A
    Delta-Notch Signaling Pathway JAG2; HES6; CNTF; TLE1; ADAM10A; ASCL1A; RING1; WDR12; SAP30; HEY1
    Developmental Biology COL4A3; DUSP1; RHOC; TRPC5; MEF2AA; DUSP4; LGI2A; CAP1; CAP2; CACNG2
    L1CAM interactions NRP2; SCN9A; DPYSL2; SCN2A; KCNQ3; SCN3B; NADL1.1; SCN3A; SDCBP; CNTN6
    NOTCH2 Activation and Transmission of Signal to the Nucleus MDK; MIB1; MDKB; MDKA; CNTN1
    Neurofascin interactions DCX; SDCBP; CNTN1

    CNTN1 has several biochemical functions, for example, carbohydrate binding, glycoprotein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CNTN1 itself. We selected most functions CNTN1 had, and list some proteins which have the same functions with CNTN1. You can find most of the proteins on our site.

    Function Related Protein
    carbohydrate binding SORD; CLEC4M; LAYN; NOMO1; ASGR1; CLEC3A; CLEC2H; CLEC7A; CD209; CHI3L1
    glycoprotein binding RAB14; RASA1; APOH; ITGB2; FYN; LCK; F7; CANX; IGF2R; SERPINA1

    CNTN1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CNTN1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CNTN1.

    PROP1; PPP1CA; MAPK6; HTT

    Querol, L; Nogales-Gadea, G; et al. Antibodies to contactin-1 in chronic inflammatory demyelinating polyneuropathy. ANNALS OF NEUROLOGY 73:370-380(2013).
    Davisson, MT; Bronson, RT; et al. A Spontaneous Mutation in Contactin 1 in the Mouse. PLOS ONE 6:-(2011).

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