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Official Full Name collagen, type VIII, alpha 1
Background This gene encodes one of the two alpha chains of type VIII collagen. The gene product is a short chain collagen and a major component of the basement membrane of the corneal endothelium. The type VIII collagen fibril can be either a homo- or a heterotrimer. Alternatively spliced transcript variants encoding the same isoform have been observed.
Synonyms COL8A1; collagen, type VIII, alpha 1; C3orf7, chromosome 3 open reading frame 7; collagen alpha-1(VIII) chain; MGC9568; C3orf7; CO8A1_HUMAN; Collagen alpha 1(VIII) chain [Precursor]; Endothelial collagen; Vastatin; OTTHUMP00000192896; OTTHUMP00000192897; collagen VIII, alpha-1 polypeptide; cell proliferation-inducing protein 41; smooth muscle cell-expressed and macrophage conditioned medium-induced protein smag-64
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Tag :
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human COL8A1-11440H Recombinant Human COL8A1, His-tagged E.coli His
    Human COL8A1-140H Recombinant Human COL8A1, His-tagged E.coli His
    Human COL8A1-7376HCL Recombinant Human COL8A1 293 Cell Lysate HEK293 N/A
    Mouse Col8a1-338M Recombinant Mouse Col8a1 Protein, His-tagged E.coli His
    Mouse COL8A1-3752M Recombinant Mouse COL8A1 Protein Mammalian Cell His
    Rat Col8a1-339R Recombinant Rat Col8a1 Protein, His-tagged E.coli His
    Chicken COL8A1-5533C Recombinant Chicken COL8A1 Mammalian Cell His

    COL8A1 involved in several pathways and played different roles in them. We selected most pathways COL8A1 participated on our site, such as Assembly of collagen fibrils and other multimeric structures, Collagen biosynthesis and modifying enzymes, Collagen formation, which may be useful for your reference. Also, other proteins which involved in the same pathway with COL8A1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Assembly of collagen fibrils and other multimeric structures LOXL2; COL11A1B; COL8A2; COL8A1; TLL1; PLEC; COL4A5; COL5A3B; COL4A4; ABHD1
    Collagen biosynthesis and modifying enzymes LEPREL2; COL4A5; COL6A2; COL8A2; PRP; COL19A1; SERPINH1; BMP1B; COL8A1A; BMP1
    Collagen formation COL5A3A; SERPINH1A; COL15A1B; ADAMTS2; COL25A1; COL19A1; PPIB; COL28A1D; COL9A3; CD151
    Extracellular matrix organization COL9A1A; COL28A1A; MFAP5; COL1A1; CTSLL; CEACAM8; LOC100514666; SERPINH1A; FBLN1; ADAM9

    COL8A1 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by COL8A1 itself. We selected most functions COL8A1 had, and list some proteins which have the same functions with COL8A1. You can find most of the proteins on our site.

    Function Related Protein
    protein binding KRTAP5-6; FBXO5; NOS1; AMY1A; RCC1; PAF1; PSRC1; LIMK2; ROPN1B; GINS4

    COL8A1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with COL8A1 here. Most of them are supplied by our site. Hope this information will be useful for your research of COL8A1.

    KRTAP26-1; KRTAP10-7; KRTAP10-8; SP4; CREB5; REL

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