| Official Full Name | collagen, type VIII, alpha 1 |
| Background | This gene encodes one of the two alpha chains of type VIII collagen. The gene product is a short chain collagen and a major component of the basement membrane of the corneal endothelium. The type VIII collagen fibril can be either a homo- or a heterotrimer. Alternatively spliced transcript variants encoding the same isoform have been observed. |
| Synonyms | COL8A1; collagen, type VIII, alpha 1; C3orf7, chromosome 3 open reading frame 7; collagen alpha-1(VIII) chain; MGC9568; C3orf7; CO8A1_HUMAN; Collagen alpha 1(VIII) chain [Precursor]; Endothelial collagen; Vastatin; OTTHUMP00000192896; OTTHUMP00000192897; collagen VIII, alpha-1 polypeptide; cell proliferation-inducing protein 41; smooth muscle cell-expressed and macrophage conditioned medium-induced protein smag-64 |
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|
col8a1 involved in several pathways and played different roles in them. We selected most pathways col8a1 participated on our site, such as Assembly of collagen fibrils and other multimeric structures, Collagen biosynthesis and modifying enzymes, Collagen formation, which may be useful for your reference. Also, other proteins which involved in the same pathway with col8a1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Assembly of collagen fibrils and other multimeric structures | CTSS; COL11A1B; COL4A5; DST; COL5A3B; COL3A1; MMP13; COL5A2; COL10A1A; COL4A4 |
| Collagen biosynthesis and modifying enzymes | COL11A1B; PPIB; SERPINH1A; COL9A3; LEPREL1; COL10A1; COL5A2; PRP; LEPRE1; COL25A1 |
| Collagen formation | SERPINH1; ABHD1; PPIB; COL9A1A; COL5A2; LOXL1; COL17A1A; SERPINH1A; COL10A1; COL4A3 |
| Extracellular matrix organization | EFEMP2; ELANE; COL13A1; ADAM8A; COL5A3A; COL17A1; FN1B; COL8A1; TIMP2A; LEPREL1 |
col8a1 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by col8a1 itself. We selected most functions col8a1 had, and list some proteins which have the same functions with col8a1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | JAG1; DDX11; GLMN; SFTPC; HIST1H2BE; TRIM37; PLP1; CCDC9; VSTM2L; MPRIP |
col8a1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with col8a1 here. Most of them are supplied by our site. Hope this information will be useful for your research of col8a1.
KRTAP26-1; KRTAP10-7; KRTAP10-8; SP4; CREB5; REL
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