CUX1

  • Official Full Name

    cut-like homeobox 1

  • Overview

    The protein encoded by this gene is a member of the homeodomain family of DNA binding proteins. It may regulate gene expression, morphogenesis, and differentiation and it may also play a role in the cell cycle progession. Several alternatively spliced transcript variants encoding different isoforms have been identified.
  • Synonyms

    CUX1; cut-like homeobox 1; cut (Drosophila) like 1 (CCAAT displacement protein) , cut like 1, CCAAT displacement protein (Drosophila) , CUTL1; protein CASP; CASP; CDP; CDP/Cut; CDP/Cux; CDP1; Clox; CUT; CUX; Cux/CDP; golgi integral membrane protein 6; GO;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Chicken
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • E.coli
  • E.coli expression system
  • HEK293
  • HEK293T
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • Myc
  • DDK
  • Myc|DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CUX1-11709H Recombinant Human CUX1, GST-tagged E.coli GST C-term-341a.a.
Human CUX1-2139H Recombinant Human CUX1 Protein, GST-tagged Wheat Germ GST
Human CUX1-424HCL Recombinant Human CUX1 cell lysate N/A
Human CUX1-3381H Recombinant Human CUX1 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human CUX1-2756H Recombinant Human CUX1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human CUX1-301226H Recombinant Human CUX1 protein, GST-tagged E.coli GST Met1-Ser341
Human CUX1-3332H Recombinant Human CUX1 protein, His-tagged E.coli His 1-341 aa
Mouse Cux1-2382M Recombinant Mouse Cux1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mus musculus (Mouse) RFL26395MF Recombinant Full Length Mouse Protein Casp(Cux1) Protein, His-Tagged E.coli expression system His Full Length (1-678)
Chicken CUX1-5492C Recombinant Chicken CUX1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

CUX1 involved in several pathways and played different roles in them. We selected most pathways CUX1 participated on our site, such as Disease, Diseases of signal transduction, FGFR1 mutant receptor activation, which may be useful for your reference. Also, other proteins which involved in the same pathway with CUX1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
DiseaseMMAA;MIB1;FDX1;AP2M1;SFTPC;CHMP4B;SUPT5H;KPNA5;RBP1
Diseases of signal transductionRLBP1;KREMEN1;RBP1;TTR;TRIM24;MYO18A;MIB1;OPN1MW;JAG1
FGFR1 mutant receptor activationLRRFIP1;CUX1;CPSF6;MYO18A;FGFR1OP;TRIM24;FGFR1OP2
Signaling by FGFR in diseaseFGFR1OP2;LRRFIP1;TRIM24;MYO18A;CUX1;CPSF6
Signaling by FGFR1 fusion mutantsCPSF6;MYO18A;CUX1;FGFR1OP2;TRIM24
Signaling by FGFR1 in diseaseCUX1;MYO18A;FGFR1OP2;TRIM24;CPSF6

CUX1 has several biochemical functions, for example, RNA polymerase II regulatory region sequence-specific DNA binding, chromatin binding, protein binding, bridging. Some of the functions are cooperated with other proteins, some of the functions could acted by CUX1 itself. We selected most functions CUX1 had, and list some proteins which have the same functions with CUX1. You can find most of the proteins on our site.

Function Related Protein
RNA polymerase II regulatory region sequence-specific DNA bindingETV3;PRKCBP1L;ZFP583;BARX1;EGR1;ZBTB4;ETV6;TBX5;MYOG
chromatin bindingUBTF;SKOR2;NR5A2;FOXC1A;ANKRD2;MBD1;PRKAA1;TOX4;PRDM11
protein binding, bridgingNEFH;FKBP4;PSMC6;NMD3;FLRT1;FSCN1A;BFAR;CRADD;FRMD4A
sequence-specific DNA bindingPOU2F3;FOXQ1A;DLX1A;HOXB3A;HOXB6;CSRNP1;PBX2;SCAND2P;FLI1A
transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific bindingHCFC1;MEOX2;SUB1;SFPI1;ZEB2;NFATC1;HMGA1;PBX3;ARID3B

CUX1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CUX1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CUX1.

RB1; BIN1; CA12; RECQL5; MAX; q7cl32_yerpe; narX; ELAC2

Research Area

Related articles

Gan, XT; Zhao, GJ; et al. Identification of Fat Mass and Obesity Associated (FTO) Protein Expression in Cardiomyocytes: Regulation by Leptin and Its Contribution to Leptin-Induced Hypertrophy. PLOS ONE 8:-(2013).
Ikeda, T; Kumagai, E; et al. Soluble CD26/Dipeptidyl Peptidase IV Enhances the Transcription of IL-6 and TNF-alpha in THP-1 Cells and Monocytes. PLOS ONE 8:-(2013).
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