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CYB5R4

  • Official Full Name

    cytochrome b5 reductase 4

  • Overview

    NCB5OR is a flavohemoprotein that contains functional domains found in both cytochrome b5 (CYB5A; MIM 613218) and CYB5;reductase (CYB5R3; MIM 613213) (Zhu et al., 1999 (PubMed 10611283)).
  • Synonyms

    CYB5R4; cytochrome b5 reductase 4; NADPH cytochrome B5 oxidoreductase , NCB5OR; b5+b5R; dJ676J13.1; b5b5r; C79736; cb5/cb5R; Cb5cb5r; Cytochrome b type NAD(P)H oxidoreductase; Flavohemoprotein b5+b5R; Flavohemoprotein b5/b5R; N terminal cytochrome b5 and cytochrome b5 oxidoreductase domain containing protein; N-terminal cytochrome b5 and cytochrome b5 oxidoreductase domain-containing protein; NADPH cytochrome B5 oxidoreductase; NB5R4_HUMAN; NCB5OR; RP4 676J13.1; OTTHUMP00000016802; cytochrome b-type NAD(P)H oxidoreductase; RP4-676J13.1;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rhesus Macaque
  • Zebrafish
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CYB5R4-2219H Recombinant Human CYB5R4 Protein, GST-tagged Wheat Germ GST
Human CYB5R4-7140HCL Recombinant Human CYB5R4 293 Cell Lysate HEK293 N/A
Human CYB5R4-2838H Recombinant Human CYB5R4 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human CYB5R4-2385HF Recombinant Full Length Human CYB5R4 Protein, GST-tagged In Vitro Cell Free System GST 521 amino acids
Mouse CYB5R4-4128M Recombinant Mouse CYB5R4 Protein Mammalian Cell His
Mouse Cyb5r4-2403M Recombinant Mouse Cyb5r4 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse CYB5R4-2115M Recombinant Mouse CYB5R4 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse CYB5R4-2115M-B Recombinant Mouse CYB5R4 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque CYB5R4-1128R Recombinant Rhesus monkey CYB5R4 Protein, His-tagged Mammalian Cell His
Rhesus Macaque CYB5R4-953R Recombinant Rhesus Macaque CYB5R4 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque CYB5R4-953R-B Recombinant Rhesus Macaque CYB5R4 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish CYB5R4-2828Z Recombinant Zebrafish CYB5R4 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

CYB5R4 involved in several pathways and played different roles in them. We selected most pathways CYB5R4 participated on our site, such as Amino sugar and nucleotide sugar metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with CYB5R4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Amino sugar and nucleotide sugar metabolismNANSA;NPL;PMM1;GMPPAB;GMDS;HEXA;CMAS;CHIA.3;NAGK

CYB5R4 has several biochemical functions, for example, NAD(P)H oxidase activity, NOT NAD(P)H oxidase activity, cytochrome-b5 reductase activity, acting on NAD(P)H. Some of the functions are cooperated with other proteins, some of the functions could acted by CYB5R4 itself. We selected most functions CYB5R4 had, and list some proteins which have the same functions with CYB5R4. You can find most of the proteins on our site.

Function Related Protein
NAD(P)H oxidase activityDERL3;DUOX2;CYB5R4;KMO;AIFM1;NOX4
NOT NAD(P)H oxidase activity
cytochrome-b5 reductase activity, acting on NAD(P)HCYB5R4;POR;CYB5R3;NQO1;CYB5R2;CYB5RL;CYB5R1
heme bindingHBBE2;CYB5B;CYP3A5;CYP4F12;CYP46A1.1;CYP2V1;CYP4V7;FA2H;CYP2AA4
metal ion bindingSTK32B;ZFPM2A;SDHC;CYP2X9;PAPOLB;NEK1;NAIP7;RNF150A;TKTL2
oxidoreductase activity, acting on NAD(P)H, heme protein as acceptorCYB5R4;COX15

CYB5R4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CYB5R4 here. Most of them are supplied by our site. Hope this information will be useful for your research of CYB5R4.

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