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CYP20A1

Official Full Name

cytochrome P450, family 20, subfamily A, polypeptide 1
Overview

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein lacks one amino acid of the conserved heme binding site. It also lacks the conserved I-helix motif AGX(D,E)T, suggesting that its substrate may carry its own oxygen.
Synonyms

CYP20A1; cytochrome P450, family 20, subfamily A, polypeptide 1; cytochrome P450 20A1; CYP M; CP20A_HUMAN; Cytochrome P450 monooxygenase; MGC22229; CYP-M;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Rat
Zebrafish

Source

E.coli
HEK293
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	CYP20A1-11767H	Recombinant Human CYP20A1, His-tagged	E.coli	His	112-462a.a.	$319 / 25ug
Human	CYP20A1-2248H	Recombinant Human CYP20A1 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	CYP20A1-7124HCL	Recombinant Human CYP20A1 293 Cell Lysate	HEK293	N/A		Inquiry
Human	CYP20A1-2825H	Recombinant Human CYP20A1 protein, His-tagged	E.coli	His	112-248 aa	$319 / 25ug
Human	CYP20A1-2305HF	Recombinant Full Length Human CYP20A1 Protein, GST-tagged	In Vitro Cell Free System	GST	462 amino acids	Inquiry
Mouse	CYP20A1-4151M	Recombinant Mouse CYP20A1 Protein	Mammalian Cell	His		Inquiry
Mouse	CYP20A1-2128M	Recombinant Mouse CYP20A1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	CYP20A1-2128M-B	Recombinant Mouse CYP20A1 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rat	CYP20A1-1718R	Recombinant Rat CYP20A1 Protein	Mammalian Cell	His		Inquiry
Rat	CYP20A1-1377R-B	Recombinant Rat CYP20A1 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rat	CYP20A1-1377R	Recombinant Rat CYP20A1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Zebrafish	CYP20A1-12517Z	Recombinant Zebrafish CYP20A1	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
CYP20A1 Related Articles

CYP20A1 involved in several pathways and played different roles in them. We selected most pathways CYP20A1 participated on our site, such as cytochrome P450, metapathway biotransformation, which may be useful for your reference. Also, other proteins which involved in the same pathway with CYP20A1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
cytochrome P450	CYP2W1;POR;CYP4F12;CYP4Z1;CYB5B;CYP2A7;CYP4V2;CYB5A;CYP20A1
metapathway biotransformation	HS3ST4;CYP4V2;KCNAB1;CYP4Z1;NAA50;NAT14;RHBDL1;CYP20A1;CHST9

CYP20A1 has several biochemical functions, for example, heme binding, iron ion binding, monooxygenase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CYP20A1 itself. We selected most functions CYP20A1 had, and list some proteins which have the same functions with CYP20A1. You can find most of the proteins on our site.

Function	Related Protein
heme binding	CYP2B19;GUCY1B3;CYB5B;CYP3C1L2;CYP4F14;CYP2AA12;CYGB;JAK2;CYP2N13
iron ion binding	CYP2C38;CYP2W1;MFI2;CYP2D10;CYP2F1;CYGB;CH25HL2;CYP2B6;C14orf169
monooxygenase activity	TYR;CYP2P7;CYP4F14;FAM84B;CYP4V8;CYP2AA6;YWHABL;CYP2X9;CYP2X7
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	CYP2Y3;CYP2AA9;CYP2J6;CYP4F18;CYP1C2;CYP2AA12;CYP2K22;CYP2D9;CYP21A1

CYP20A1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CYP20A1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CYP20A1.

Rrbp1

Nyante, SJ; Gammon, MD; et al. Genetic variation in estrogen and progesterone pathway genes and breast cancer risk: an exploration of tumor subtype-specific effects. CANCER CAUSES & CONTROL 26:121-131(2015).

Zou, JG; Ma, YT; et al. The association between CYP1A1 genetic polymorphisms and coronary artery disease in the Uygur and Han of China. LIPIDS IN HEALTH AND DISEASE 13:-(2014).