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CYP2W1

Official Full Name

cytochrome P450, family 2, subfamily W, polypeptide 1
Overview

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids.
Synonyms

CYP2W1; cytochrome P450, family 2, subfamily W, polypeptide 1; cytochrome P450 2W1; FLJ20359; MGC34287; CYPIIW1;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse

Source

HEK293
HEK293T
In Vitro Cell Free System
Mammalian Cell
Mammalian cells
Wheat Germ

Tag

Flag
GST
His
His (Fc)
Avi
Myc
DDK
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	CYP2W1-2271H	Recombinant Human CYP2W1 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	CYP2W1-7107HCL	Recombinant Human CYP2W1 293 Cell Lysate	HEK293	N/A		Inquiry
Human	CYP2W1-2396HF	Recombinant Full Length Human CYP2W1 Protein, GST-tagged	In Vitro Cell Free System	GST	434 amino acids	Inquiry
Human	CYP2W1-1740HFL	Recombinant Full Length Human CYP2W1 Protein, C-Flag-tagged	Mammalian cells	Flag		Inquiry
Human	CYP2W1-705H	Recombinant Human CYP2W1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Human	CYP2W1-705H-B	Recombinant Human CYP2W1 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Mouse	CYP2W1-4204M	Recombinant Mouse CYP2W1 Protein	Mammalian Cell	His		Inquiry
Mouse	CYP2W1-2152M-B	Recombinant Mouse CYP2W1 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Mouse	CYP2W1-2152M	Recombinant Mouse CYP2W1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	Cyp2w1-2420M	Recombinant Mouse Cyp2w1 Protein, Myc/DDK-tagged	HEK293T	Myc/DDK		Inquiry

Involved Pathway
Protein Function
Interacting Protein

CYP2W1 involved in several pathways and played different roles in them. We selected most pathways CYP2W1 participated on our site, such as Biological oxidations, Cytochrome P450 - arranged by substrate type, Metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with CYP2W1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Biological oxidations	UGT1B2;GLYAT;FDXR;ACSM1;CYP2K8;SULT4A1;SLC26A1;COMT;DPEP2
Cytochrome P450 - arranged by substrate type	CYP3A4;CYP3A7-CYP3AP1;CYP3C4;CYP2A6;CYP27B1;CYP2K18;FAM84B;FDX1L;CYP4B1
Metabolism	FAM36A;Sult2a2;DHODH;NQO1;BRSK2;ADH8B;DLAT;COX14;C20orf7
Miscellaneous substrates	CYP3C4;CYP4F22;CYP2K19;CYP2K18;CYP2K17;CYP2K22;CYP2S1;CYP2K8;CYP2K6
Phase 1 - Functionalization of compounds	CYP2Y3;CYP2K17;CYP2R1;CYP2V1;CYP2AD6;CYP27B1;CYP2K19;CYP3C1;CYP2K22
Xenobiotics	CYP2A7;CYP2W1;CYP3C4;CYP3C1
cytochrome P450	CYP4V2;CYP20A1;CYP2A7;CYB5A;CYP4Z1;CYP4F12;CYP2W1;CYB5R3;POR
metapathway biotransformation	NAT9;SULT4A1;CHST8;CYP20A1;CYP2W1;KCNAB3;GAL3ST4;NAT8;GAL3ST3

CYP2W1 has several biochemical functions, for example, heme binding, iron ion binding, oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen. Some of the functions are cooperated with other proteins, some of the functions could acted by CYP2W1 itself. We selected most functions CYP2W1 had, and list some proteins which have the same functions with CYP2W1. You can find most of the proteins on our site.

Function	Related Protein
heme binding	CBS;CYP24A1;MPO;CYBA;CBSB;CYP46A1.1;CYP21A1;CYP3A4;CYP4F2
iron ion binding	CYP4A12A;NOS2B;PDF;CYP1A1;AOX3L1;CYP46A1.2;CYP2N13;BRSK2;LEPREL2
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	CYP3C1;CYP2K19;CYP2C50;CYP2K17;CYP2AA3;CYP2B19;CYP2P6;CYP2D9;CYP2C38
oxygen binding	HBBE1.1;HBB-B2;CYP2C55;CYP2K18;CYP2A7;HBQ1;CYP2X9;CYP1B1;CYP2K22
steroid hydroxylase activity	CYP2K18;CYP2A4;CYP2X9;CYP2AA12;CYP2W1;CYP2J6;CYP2K22;CYP2C19;FAM84B

CYP2W1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CYP2W1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CYP2W1.

CYB5A; ZBTB26