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CYP8B1

  • Official Full Name

    cytochrome P450, family 8, subfamily b, polypeptide 1

  • Synonyms

    CP8B; CYP12;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Oryctolagus cuniculus (Rabbit)
  • Zebrafish
  • E.coli expression system
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CYP8B1-2294H Recombinant Human CYP8B1 Protein, GST-tagged Wheat Germ GST
Human CYP8B1-2485HF Recombinant Full Length Human CYP8B1 Protein, GST-tagged In Vitro Cell Free System GST 501 amino acids
Mouse CYP8B1-4234M Recombinant Mouse CYP8B1 Protein Mammalian Cell His
Mouse CYP8B1-2164M Recombinant Mouse CYP8B1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse CYP8B1-2164M-B Recombinant Mouse CYP8B1 Protein Pre-coupled Magnetic Beads HEK293
Mus musculus (Mouse) RFL15609MF Recombinant Full Length Mouse 7-Alpha-Hydroxycholest-4-En-3-One 12-Alpha-Hydroxylase(Cyp8B1) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (2-500)
Oryctolagus cuniculus (Rabbit) RFL22297OF Recombinant Full Length Rabbit 7-Alpha-Hydroxycholest-4-En-3-One 12-Alpha-Hydroxylase(Cyp8B1) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (2-500)
Zebrafish CYP8B1-1077Z Recombinant Zebrafish CYP8B1 Mammalian Cell His
Chicken CYP8B1-1246C Recombinant Chicken CYP8B1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

CYP8B1 involved in several pathways and played different roles in them. We selected most pathways CYP8B1 participated on our site, such as Primary bile acid biosynthesis, Metabolic pathways, PPAR signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with CYP8B1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Primary bile acid biosynthesisCYP46A1.2;CYP7B1;CH25HL1.2;SCP2A;CH25HL2;SCP2;ACOX2;AKR1C4;HSD3B7
Metabolic pathwaysACSM2;PPAP2D;HYAL4;HAL;CERS5;COX6A1;TST;CKM;HYAL3
PPAR signaling pathwayFABP7B;APOA5;Scd1;MMP1A;AQP7;APOC3;SLC27A1A;Scd2;FABP6

CYP8B1 has several biochemical functions, for example, 7alpha-hydroxycholest-4-en-3-one 12alpha-hydroxylase activity, heme binding, iron ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CYP8B1 itself. We selected most functions CYP8B1 had, and list some proteins which have the same functions with CYP8B1. You can find most of the proteins on our site.

Function Related Protein
7alpha-hydroxycholest-4-en-3-one 12alpha-hydroxylase activity
heme bindingCYP46A1;DUOX2;CYP8B1;CYP26B1;HBBE3;CYP2A6;CYP2D26;HRG;CYP2AA4
iron ion bindingHBBE2;P4HTM;CYP2K22;CYP2C70;AOX4;HBZ;CYP2C50;CYP27B1;CYP4V8
metal ion bindingTNFSF10;KLF6A;PDLIM5A;TRIM55B;ZNF530;ADH8A;Trl;BCL11A;HBBE2
monooxygenase activityCYP2X8;CYP2Y3;CYP46A1.3;CYP8B2;CYP2C55;CYP2K18;CYP2K22;CYP46A1.2;CYP17A2
oxidoreductase activityENOX1;CYP2X8;CYP4T8;RDH1;NDOR1;CYP2F2;PYCR1B;CYP19A1A;AKR1B8
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygenCYP46A1.4;CYP4F14;CYP2K17;CYP4F18;CYP8B3;CYP4T8;CYP2D9;CYP2P7;CYP2X8
sterol 12-alpha-hydroxylase activity

CYP8B1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CYP8B1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CYP8B1.

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