DAPK3

  • Official Full Name

    death-associated protein kinase 3

  • Overview

    Death-associated protein kinase 3 (DAPK3) induces morphological changes in apoptosis when overexpressed in mammalian cells.These results suggest that DAPK3 may play a role in the induction of apoptosis.
  • Synonyms

    DAPK3; death-associated protein kinase 3; ZIP; ZIPK; dlk; ZIP-kinase; DAP kinase 3; MYPT1 kinase; DAP-like kinase; ZIP kinase isoform; zipper-interacting protein kinase; FLJ36473;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • E.coli
  • HEK293
  • HEK293T
  • Human
  • In Vitro Cell Free System
  • Insect (sf21)
  • Insect Cell
  • Mammalian Cell
  • Sf9 Insect Cell
  • Wheat Germ
  • DDK
  • GST
  • His
  • His (Fc)
  • Avi
  • His|T7
  • Myc
  • Myc|DDK
  • N/A
  • No tag
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human DAPK3-261H Active Recombinant Human DAPK3(1-290) Protein, N-GST-tagged E.coli His 1-290 aa
Human DAPK3-291H Recombinant Human DAPK3, GST-tagged, Active Sf9 Insect Cell GST
Human DAPK3-292H Recombinant Human DAPK3, 1-659, GST-tagged, Active Sf9 Insect Cell GST
Human DAPK3-892H Recombinant Human Death-Associated Protein Kinase 3, GST-tagged Human GST
Human DAPK3-30752TH Recombinant Human DAPK3 N/A
Human DAPK3-2340H Active Recombinant Human DAPK3 Protein, GST-tagged Insect Cell GST
Human DAPK3-2341H Recombinant Human DAPK3 Protein, GST-tagged Wheat Germ GST
Human DAPK3-616HCL Recombinant Human DAPK3 cell lysate Insect Cell N/A
Human DAPK3-984H Recombinant Human DAPK3 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human DAPK3-4921HF Active Recombinant Full Length Human DAPK3 Protein, DDK-tagged, Biotinylated Insect (sf21) DDK 1-454(end)
Human DAPK3-2511HF Recombinant Full Length Human DAPK3 Protein, GST-tagged In Vitro Cell Free System GST 454 amino acids
Human DAPK3-1124H Recombinant Human DAPK3 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human DAPK3-1096H Recombinant Human DAPK3 Protein (S2-R454), Tag Free Insect Cell No tag S2-R454
Human DAPK3-9693HF Active Recombinant Full Length Human DAPK3 Protein, GST-tagged Insect (sf21) GST 1-454(end)
Human DAPK3-1097H Recombinant Human DAPK3 Protein (S2-R454), GST tagged Insect Cell GST S2-R454
Mouse DAPK3-4306M Recombinant Mouse DAPK3 Protein Mammalian Cell His
Mouse Dapk3-1405M Recombinant Mouse Dapk3 protein, His & T7-tagged E.coli His/T7 Met1~Arg448 (Accession # O54784)
Mouse DAPK3-2202M Recombinant Mouse DAPK3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Dapk3-2453M Recombinant Mouse Dapk3 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse DAPK3-2202M-B Recombinant Mouse DAPK3 Protein Pre-coupled Magnetic Beads HEK293
Rat DAPK3-1775R Recombinant Rat DAPK3 Protein Mammalian Cell His
Rat DAPK3-1433R Recombinant Rat DAPK3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat DAPK3-1433R-B Recombinant Rat DAPK3 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque DAPK3-1177R Recombinant Rhesus monkey DAPK3 Protein, His-tagged Mammalian Cell His
Rhesus Macaque DAPK3-1002R Recombinant Rhesus Macaque DAPK3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque DAPK3-1002R-B Recombinant Rhesus Macaque DAPK3 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

DAPK3 involved in several pathways and played different roles in them. We selected most pathways DAPK3 participated on our site, such as Apoptosis, Bladder cancer, Caspase activation via extrinsic apoptotic signalig pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with DAPK3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
ApoptosisGAS2;PANK1A;PIK3R3;CASP10;NFKBIA;IRF1B;NFKBIAA;CFLARA;PTBP3
Bladder cancerTYMP;MDM2;ARAF;MMP2;DAPK1;MMP9;BRAF;ERBB2;UPK3A
Caspase activation via extrinsic apoptotic signalig pathwayRNF8;TICAM1;DAPK1;DCC;DAPK3;CASP8L1
Ligand-independent caspase activation via DCCRNF8;DAPK1;DAPK3
Pathways in cancerTPR;LPAR5;CASP8;CUL2;SMAD4;NKX3-1;PLCB2;ZBTB16;GNG12
Programmed Cell DeathBAXB;DBNLA;PKP1;SATB1;HMGB2;DIABLO;HMGB2A;MLKL;DBNL

DAPK3 has several biochemical functions, for example, ATP binding, Rho GTPase binding, cAMP response element binding protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DAPK3 itself. We selected most functions DAPK3 had, and list some proteins which have the same functions with DAPK3. You can find most of the proteins on our site.

Function Related Protein
ATP bindingUCK2B;HSPA9;KIF18B;IP6K2;ABCD4;NOD1;SLFNL1;TEX14;KIF23
Rho GTPase bindingDAAM1;ARHGEF2;ARHGEF16;RHOH;DIAPH1;ROCK2;CSDA;DOCK9;IQGAP3
cAMP response element binding protein bindingATF2;CRTC3;CRTC2;CRTC1A;DAPK3;CRTC1;KCNA3;CREB3;CREM
identical protein bindingKCTD13;BCHE;KCNIP2;ADORA2A;SMAD4;ADIPOQ;NOXO1;TYSND1;MCIN
leucine zipper domain bindingDAPK3;KCNA3;NRL;ERC1;ATF4;DDIT3;MKL1;CRX;PMF1
protein bindingUGP2;THAP3;CCDC85B;LOXL4;MICAL1;CADM1;COBRA1;ARL8A;PID1
protein homodimerization activityDARS2;HINT2;CLN6;CUBN;LILRB1;PYGB;ASMT;DMRTA2;VPS4B
protein serine/threonine kinase activityRAF1A;PINK1;BMPR1AA;MAPK14A;MAP3K2;PLK3;PHKG1A;TBK1;MAP2K7

DAPK3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DAPK3 here. Most of them are supplied by our site. Hope this information will be useful for your research of DAPK3.

TCP10L; PPP1R12A; MYL12B; Daxx; HSP90AB1; ATF4; STAT3; Rhod; CDC37

Research Area

Related articles

Marina, O; Hainz, U; et al. Serologic Markers of Effective Tumor Immunity against Chronic Lymphocytic Leukemia Include Nonmutated B-Cell Antigens. CANCER RESEARCH 70:1344-1355(2010).
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