DPP8 Protein


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Official Full Name dipeptidyl-peptidase 8
Background This gene encodes a member of the peptidase S9B family, a small family of dipeptidyl peptidases that are able to cleave peptide substrates at a prolyl bond. The encoded protein shares similarity with dipeptidyl peptidase IV in that it is ubiquitously expressed, and hydrolyzes the same substrates. These similarities suggest that, like dipeptidyl peptidase IV, this protein may play a role in T-cell activation and immune function. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Synonyms DPP8; dipeptidyl-peptidase 8; DP8; DPRP1; MSTP141; dipeptidyl peptidase 8; DPRP-1; DPP VIII; dipeptidylpeptidase 8; prolyl dipeptidase DPP8; dipeptidyl peptidase VIII; dipeptidyl peptidase IV-related protein 1; dipeptidyl peptidase IV-related protein-1;
    • Species :
    • Human
    • Mouse
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • In Vitro Cell Free System
    • Mammalian Cell
    • Sf9 Insect Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • Myc/DDK
    • N/A
    • N-His
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human DPP8-1063H Recombinant Human DPP8 protein, His-tagged E.coli His
    Human DPP8-28436TH Recombinant Human DPP8 N/A
    Human DPP8-2849H Recombinant Human DPP8 Protein, GST-tagged Wheat Germ GST
    Human DPP8-516H Recombinant Human Dipeptidyl-Peptidase 8, GST-tagged Sf9 Insect Cell GST
    Mouse DPP8-4797M Recombinant Mouse DPP8 Protein Mammalian Cell His
    Human DPP8-6829HCL Recombinant Human DPP8 293 Cell Lysate HEK293 N/A
    Human DPP8-6830HCL Recombinant Human DPP8 293 Cell Lysate HEK293 N/A
    Mouse Dpp8-1376M Recombinant Mouse Dpp8 Protein, His-tagged E.coli N-His
    Human DPP8-4147HF Recombinant Full Length Human DPP8 Protein, GST-tagged In Vitro Cell Free System GST
    Mouse Dpp8-2644M Recombinant Mouse Dpp8 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Kit-1719 DPP8 Assay Kit N/A

    DPP8 involved in several pathways and played different roles in them. We selected most pathways DPP8 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with DPP8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    DPP8 has several biochemical functions, for example, dipeptidyl-peptidase activity, serine-type peptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by DPP8 itself. We selected most functions DPP8 had, and list some proteins which have the same functions with DPP8. You can find most of the proteins on our site.

    Function Related Protein
    dipeptidyl-peptidase activity DPP3; FAP; DPEP1; DPP4; NAALAD2; PRCP; DPP8; DPEP3; DPP7; DPEP2
    serine-type peptidase activity PREP; ELA2L; OVCH2; Reln; DPP4; TPP1; PRSS59.2; GZMF; PRSS30; PRSS12

    DPP8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DPP8 here. Most of them are supplied by our site. Hope this information will be useful for your research of DPP8.

    CXCL11; CXCL10; p48061-1; p48061-2

    Justa-Schuch, D; Moller, U; et al. The amino terminus extension in the long dipeptidyl peptidase 9 isoform contains a nuclear localization signal targeting the active peptidase to the nucleus. CELLULAR AND MOLECULAR LIFE SCIENCES 71:3611-3626(2014).
    Harstad, EB; Rosenblum, JS; et al. DPP8 and DPP9 expression in cynomolgus monkey and Sprague Dawley rat tissues. REGULATORY PEPTIDES 186:26-35(2013).

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