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Official Full Name elaC homolog 1 (E. coli)
Background ElaC homolog protein 1 (ELAC1) is a zinc phosphodiesterase, which displays some tRNA 3-processing endonuclease activity. It is probably involved in tRNA maturation, by removing a 3 trailer from precursor tRNA.
Synonyms ELAC1; elaC homolog 1 (E. coli); elaC (E. coli) homolog 1; zinc phosphodiesterase ELAC protein 1; D29; tRNA Z (short form); Deleted in Ma29; ELAC 1; ElaC homolog 1; ElaC homolog protein 1; Ribonuclease Z 1; RNase Z 1; tRNA 3 endonuclease 1; tRNA Z; tRNase Z 1; tRNase ZS; OTTHUMP00000163547; tRNA 3 processing endoribonuclease
    • Species :
    • Human
    • Mouse
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • MYC/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ELAC1-2236H Recombinant Human ELAC1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human ELAC1-3227H Recombinant Human ELAC1 Protein, GST-tagged Wheat Germ GST
    Human ELAC1-6639HCL Recombinant Human ELAC1 293 Cell Lysate HEK293 N/A
    Human ELAC1-96H Recombinant Human ELAC1, His-tagged E.coli His
    Mouse ELAC1-5120M Recombinant Mouse ELAC1 Protein Mammalian Cell His
    Mouse Elac1-520M Recombinant Mouse Elac1 Protein, MYC/DDK-tagged HEK293T MYC/DDK
    Zebrafish ELAC1-944Z Recombinant Zebrafish ELAC1 Mammalian Cell His

    elac1 involved in several pathways and played different roles in them. We selected most pathways elac1 participated on our site, such as RNA transport, which may be useful for your reference. Also, other proteins which involved in the same pathway with elac1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    RNA transport PAIP1; NCBP2; GEMIN8; NUP160; SUMO4; TGS1; EEF1A1L1; UBE2IB; EIF1B; NXT2

    elac1 has several biochemical functions, for example, 3-tRNA processing endoribonuclease activity, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by elac1 itself. We selected most functions elac1 had, and list some proteins which have the same functions with elac1. You can find most of the proteins on our site.

    Function Related Protein
    3-tRNA processing endoribonuclease activity ELAC2; ELAC1
    metal ion binding PHYHD1; PVALB2; NR2F6A; DNLZ; RPE65; ZMYM2; ZNF829; STEAP1; TRIM35-1; DNAJC21

    elac1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with elac1 here. Most of them are supplied by our site. Hope this information will be useful for your research of elac1.

    Huhn, S; Bevier, M; et al. Colorectal cancer risk and patients' survival: influence of polymorphisms in genes somatically mutated in colorectal tumors. CANCER CAUSES & CONTROL 25:759-769(2014).
    Rossmanith, W; et al. Localization of Human RNase Z Isoforms: Dual Nuclear/Mitochondrial Targeting of the ELAC2 Gene Product by Alternative Translation Initiation. PLOS ONE 6:-(2011).

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