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ELF1

  • Official Full Name

    E74-like factor 1 (ets domain transcription factor)

  • Overview

    This gene encodes an E26 transformation-specific related transcription factor. The encoded protein is primarily expressed in lymphoid cells and acts as both an enhancer and a repressor to regulate transcription of various genes. Alternative splicing results in multiple transcript variants.
  • Synonyms

    ELF1; E74-like factor 1 (ets domain transcription factor); ETS-related transcription factor Elf-1; mElf 1; E74 like factor 1; ELF 1; Ets domain transcription factor; ETS related transcription factor Elf 1; ETS related transcription factor Elf1; p70; Sts1; TRANSCRIPTION FACTOR ELF 1; OTTHUMP00000018310;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Rhesus Macaque
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • HIS
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human ELF1-3236H Recombinant Human ELF1 Protein, GST-tagged Wheat Germ GST
Human ELF1-12399H Recombinant Human ELF1, GST-tagged E.coli GST 320-618a.a.
Human ELF1-095H Recombinant Human ELF1 Protein, HIS-tagged E.coli HIS
Human ELF1-548HCL Recombinant Human ELF1 cell lysate N/A
Human ELF1-4341HF Recombinant Full Length Human ELF1 Protein, GST-tagged In Vitro Cell Free System GST 619 amino acids
Human ELF1-1348HFL Recombinant Full Length Human ELF1 Protein, N-His-tagged E.coli His
Rhesus Macaque ELF1-1438R Recombinant Rhesus monkey ELF1 Protein, His-tagged Mammalian Cell His
Rhesus Macaque ELF1-1262R-B Recombinant Rhesus Macaque ELF1 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque ELF1-1262R Recombinant Rhesus Macaque ELF1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Chicken ELF1-1416C Recombinant Chicken ELF1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • ELF1 Related Research Area

ELF1 involved in several pathways and played different roles in them. We selected most pathways ELF1 participated on our site, such as Angiopoietin receptor Tie2-mediated signaling, IL2 signaling events mediated by STAT5, Regulation of retinoblastoma protein, which may be useful for your reference. Also, other proteins which involved in the same pathway with ELF1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Angiopoietin receptor Tie2-mediated signalingDOK2;ELF1;BMX;AGTR1;GRB14;ELF2;CDKN1A;CRK;GRB7
IL2 signaling events mediated by STAT5
Regulation of retinoblastoma proteinATF7;ELF1;AATF;BRD2;GSC;SMARCB1;CBX4;CKM;MYOD1

ELF1 has several biochemical functions, for example, RNA polymerase II core promoter proximal region sequence-specific DNA binding, protein binding, transcription factor activity, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ELF1 itself. We selected most functions ELF1 had, and list some proteins which have the same functions with ELF1. You can find most of the proteins on our site.

Function Related Protein
RNA polymerase II core promoter proximal region sequence-specific DNA bindingFOXD1;KLF17;T;OTX2;NFE2L3;ZNF253;MZF1;ASCL1;MED1
protein bindingPLCG1;PHB2;ASB2;SEPT10;DRD1A;RIPPLY2;RTN4RL1;VPS72;LMO4
transcription factor activity, sequence-specific DNA bindingELK4;FOS;ELF1;KAT7;MYBL2;TBX2B;HOXB2;MSRB2;ZBTB48
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific bindingNKX2;EGR2;HNRNPK;CAMTA2;NEUROD1;POU4F2;KLF4;CEBPA;NR1H4

ELF1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ELF1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ELF1.

HOXC13; SP1; purL; flgE; htrA; q81sn0_bacan; ecfA1; fusA; ligA; mdtA; q9zc29_yerpe; dsdna_dadg:dcdt; BCL6

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