|Official Full Name||E74-like factor 1 (ets domain transcription factor)|
|Background||This gene encodes an E26 transformation-specific related transcription factor. The encoded protein is primarily expressed in lymphoid cells and acts as both an enhancer and a repressor to regulate transcription of various genes. Alternative splicing results in multiple transcript variants.|
|Synonyms||ELF1; E74-like factor 1 (ets domain transcription factor); ETS-related transcription factor Elf-1; mElf 1; E74 like factor 1; ELF 1; Ets domain transcription factor; ETS related transcription factor Elf 1; ETS related transcription factor Elf1; p70; Sts1; TRANSCRIPTION FACTOR ELF 1; OTTHUMP00000018310|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
elf1 involved in several pathways and played different roles in them. We selected most pathways elf1 participated on our site, such as Angiopoietin receptor Tie2-mediated signaling, IL2 signaling events mediated by STAT5, Regulation of retinoblastoma protein, which may be useful for your reference. Also, other proteins which involved in the same pathway with elf1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Angiopoietin receptor Tie2-mediated signaling||ELF2; CDKN1A; GRB7; GRB14; BMX; DOK2; CRK; ELF1; AGTR1|
|IL2 signaling events mediated by STAT5||ELF1|
|Regulation of retinoblastoma protein||AATF; BGLAP; GSC; BRD2; ELF1; SMARCB1; ATF7; CKM; MYOD1; CBX4|
elf1 has several biochemical functions, for example, RNA polymerase II core promoter proximal region sequence-specific DNA binding, protein binding, transcription factor activity, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by elf1 itself. We selected most functions elf1 had, and list some proteins which have the same functions with elf1. You can find most of the proteins on our site.
|RNA polymerase II core promoter proximal region sequence-specific DNA binding||GZF1; ETV6; SIX4; NKX6-1; MIXL1; RFX3; PER1; GATA1; KDM6A; SMAD2|
|protein binding||TAF1; MED17; NUB1; EIF3D; ZNF274; NEK3; STT3A; PDLIM2; CHAC1; ICAM3|
|transcription factor activity, sequence-specific DNA binding||ATOH1; RFX1A; MAFA; ZIC5; ZNF37A; LHX8A; RELB; SIM1; PAX7; ONECUT3|
|transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding||TCF12; GATA2; SP1; ZIC3; CAMTA2; ELF1; STAT3; MITF; MEF2C; DBP|
elf1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with elf1 here. Most of them are supplied by our site. Hope this information will be useful for your research of elf1.
HOXC13; SP1; purL; flgE; htrA; q81sn0_bacan; ecfA1; fusA; ligA; mdtA; q9zc29_yerpe; dsdna_dadg:dcdt; BCL6