ELF1

Official Full Name

E74-like factor 1 (ets domain transcription factor)
Overview

This gene encodes an E26 transformation-specific related transcription factor. The encoded protein is primarily expressed in lymphoid cells and acts as both an enhancer and a repressor to regulate transcription of various genes. Alternative splicing results in multiple transcript variants.
Synonyms

ELF1; E74-like factor 1 (ets domain transcription factor); ETS-related transcription factor Elf-1; mElf 1; E74 like factor 1; ELF 1; Ets domain transcription factor; ETS related transcription factor Elf 1; ETS related transcription factor Elf1; p70; Sts1; TRANSCRIPTION FACTOR ELF 1; OTTHUMP00000018310;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
Rhesus Macaque

Source

E.coli
HEK293
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	ELF1-3236H	Recombinant Human ELF1 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	ELF1-12399H	Recombinant Human ELF1, GST-tagged	E.coli	GST	320-618a.a.	$319 / 25μg
Human	ELF1-095H	Recombinant Human ELF1 Protein, HIS-tagged	E.coli	HIS		Inquiry
Human	ELF1-548HCL	Recombinant Human ELF1 cell lysate		Non		Inquiry
Human	ELF1-4341HF	Recombinant Full Length Human ELF1 Protein, GST-tagged	In Vitro Cell Free System	GST	619 amino acids	Inquiry
Human	ELF1-1348HFL	Recombinant Full Length Human ELF1 Protein, N-His-tagged	E.coli	His		Inquiry
Rhesus Macaque	ELF1-1438R	Recombinant Rhesus monkey ELF1 Protein, His-tagged	Mammalian Cell	His		Inquiry
Rhesus Macaque	ELF1-1262R-B	Recombinant Rhesus Macaque ELF1 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rhesus Macaque	ELF1-1262R	Recombinant Rhesus Macaque ELF1 Protein, His (Fc)-Avi-tagged	HEK293	His&Fc&Avi		Inquiry
Chicken	ELF1-1416C	Recombinant Chicken ELF1	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
Other Resource

ELF1 involved in several pathways and played different roles in them. We selected most pathways ELF1 participated on our site, such as Angiopoietin receptor Tie2-mediated signaling, IL2 signaling events mediated by STAT5, Regulation of retinoblastoma protein, which may be useful for your reference. Also, other proteins which involved in the same pathway with ELF1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Angiopoietin receptor Tie2-mediated signaling	GRB14;DOK2;CDKN1A;CRK;ELF2;AGTR1;ELF1;GRB7;BMX
IL2 signaling events mediated by STAT5
Regulation of retinoblastoma protein	MYOD1;ELF1;AATF;CKM;GSC;ATF7;SMARCB1;CBX4;BRD2

ELF1 has several biochemical functions, for example, RNA polymerase II core promoter proximal region sequence-specific DNA binding, protein binding, transcription factor activity, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ELF1 itself. We selected most functions ELF1 had, and list some proteins which have the same functions with ELF1. You can find most of the proteins on our site.

Function	Related Protein
RNA polymerase II core promoter proximal region sequence-specific DNA binding	ATF7;BATF2;TFE3A;STAT3;DDN;ZNF502;ELF4;CRX;ZFP746
protein binding	RARS;TMEM86B;EDNRA;GGT1;CENPI;SUPT5H;BOLA1;SPTAN1;FBXO46
transcription factor activity, sequence-specific DNA binding	BTBD8;ZNF75D;IRF4A;MTA2;TP73;MEF2B;L3MBTL1;FOXG1D;TBX4
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding	KLF4;CEBPA;SOX12;MYBL1;MTF1;TXK;PPARA;MEIS3;SOX1

ELF1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ELF1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ELF1.

HOXC13; SP1; purL; flgE; htrA; q81sn0_bacan; ecfA1; fusA; ligA; mdtA; q9zc29_yerpe; dsdna_dadg:dcdt; BCL6