ELP3

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ELP3

Official Full Name elongation protein 3 homolog
Background ELP3 is the catalytic subunit of the histone acetyltransferase elongator complex, which contributes to transcript;elongation and also regulates the maturation of projection neurons (Creppe et al., 2009 (PubMed 19185337)).
Synonyms ELP3; elongation protein 3 homolog (S. cerevisiae); elongator complex protein 3; FLJ10422; KAT9; hELP3
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • Mammalian Cell
    • Sf9 Insect Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ELP3-12424H Recombinant Human ELP3, GST-tagged E.coli GST
    Human ELP3-1583H Recombinant Human Elongation Protein 3 Homolog (S. Cerevisiae), GST-tagged Sf9 Insect Cell GST
    Human ELP3-3264H Recombinant Human ELP3 Protein, GST-tagged Wheat Germ GST
    Human ELP3-551HCL Recombinant Human ELP3 cell lysate N/A
    Mouse ELP3-5155M Recombinant Mouse ELP3 Protein Mammalian Cell His
    Rhesus Macaque ELP3-1455R Recombinant Rhesus monkey ELP3 Protein, His-tagged Mammalian Cell His
    Chicken ELP3-3353C Recombinant Chicken ELP3 Mammalian Cell His
    Zebrafish ELP3-2250Z Recombinant Zebrafish ELP3 Mammalian Cell His

    ELP3 involved in several pathways and played different roles in them. We selected most pathways ELP3 participated on our site, such as Chromatin modifying enzymes, Chromatin organization, HATs acetylate histones, which may be useful for your reference. Also, other proteins which involved in the same pathway with ELP3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Chromatin modifying enzymes MBD3B; DNMT3A; EPC1; KAT7A; RBBP7; JMJD6; PADI2; CARM1; PBRM1; BRMS1
    Chromatin organization KAT7; KANSL3; KDM1A; YEATS4; C17orf81; MSL2; RBBP4; KDM3B; PRDM16; CHD4
    HATs acetylate histones RUVBL2; MSL2; ING5B; PAX3A; RBB4L; ANO9A; PHF17; MORF4L2; MSL3; KAT6A

    ELP3 has several biochemical functions, for example, H3 histone acetyltransferase activity, H4 histone acetyltransferase activity, contributes_to RNA polymerase II core binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ELP3 itself. We selected most functions ELP3 had, and list some proteins which have the same functions with ELP3. You can find most of the proteins on our site.

    Function Related Protein
    H3 histone acetyltransferase activity KAT2A; ELP3; BRCA2
    H4 histone acetyltransferase activity NAT15; HAT1; NAA50; BRCA2; ELP3; NAA60
    contributes_to RNA polymerase II core binding ELP3; ELP2; ELP4; IKBKAP
    iron-sulfur cluster binding PROZA; REV3L; RPS3; ISCUB; FDX1B; AIFM4; CISD3; CMAH; ABAT; PRIM2
    metal ion binding TRIM43B; LNPA; FAHD2A; ZDHHC15A; VAV3B; ZFP239; CNOT6L; GTF3AB; HRG; MARCH4
    phosphorylase kinase regulator activity PRKAG2; ELP4; IKBKAP; ELP3
    protein binding JAG2; TRIM42; SMU1; PLGRKT; DOK2; RHOBTB3; GNMT; SEPT5; TCTEX1D2; EVI5L

    ELP3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ELP3 here. Most of them are supplied by our site. Hope this information will be useful for your research of ELP3.

    IKBKAP; POLR2A; NFKBIA; ELP5; ELP4

    Gu, JX; Sun, DM; et al. Human Elongator complex is involved in cell cycle and suppresses cell growth in 293T human embryonic kidney cells. ACTA BIOCHIMICA ET BIOPHYSICA SINICA 41:831-838(2009).
    Barton, D; Braet, F; et al. ELP3 localises to mitochondria and actin-rich domains at edges of HeLa cells. NEUROSCIENCE LETTERS 455:60-64(2009).
    Klassen, R; Meinhardt, F; et al. Structural and functional analysis of the killer element pPin1-3 from Pichia inositovora. MOLECULAR GENETICS AND GENOMICS 270:190-199(2003).

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